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Rapid Communication: Neuropeptide Expression and Processing as Revealed by Direct Matrix-Assisted Laser Desorption Ionization Mass Spectrometry of Single Neurons

Autor: Willem C. Wildering, P. A. van Veelen, J. van der Greef, U.R. Tjaden, Wijnand P. M. Geraerts, Connie R. Jimenez, Ka Wan Li

Publikováno v: Journal of Neurochemistry. 62:404-407

Neuropeptides were directly detected in single identified neurons and the neurohemal area of peptidergic (neuroendocrine) systems in the Lymnaea brain by using matrix-assisted laser desorption ionization mass spectrometry (MALDI-MS). The samples were

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::cc0d83a46fd6891e26f8db1a61544b13
https://doi.org/10.1046/j.1471-4159.1994.62010404.x

Peptidomics of a single identified neuron reveals diversity of multiple neuropeptides with convergent actions on cellular excitability

Autor: Johannes C. Lodder, Connie R. Jimenez, van Minnen, J., Wijnand P. M. Geraerts, Naweed I. Syed, Sabine Spijker, Alma L. Burlingame, August B. Smit, de Schipper, S., Ka Wan Li, C. Janse

Publikováno v: Jimenez, C R, Spijker, S, de Schipper, S, Lodder, J C, Janse, C K, Geraerts, W P M, van Minnen, J, Syed, N I, Burlingame, A L, Smit, A B & Li, K W 2006, ' Peptidomics of a single identified neuron reveals diversity of multiple neuropeptides with convergent actions on cellular excitability ', The Journal of Neuroscience, vol. 26, no. 2, pp. 518-529 . https://doi.org/10.1523/JNEUROSCI.2566-05.2006
The Journal of Neuroscience, 26(2), 518-529. Society for Neuroscience

In contrast to classical transmitters, the detailed structures and cellular and synaptic actions of neuropeptides are less well described. Peptide mass profiling of single identified neurons of the mollusc Lymnaea stagnalis indicated the presence of

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fab12e669d60e0522bce8ce6b30dbcee
https://doi.org/10.1523/jneurosci.2566-05.2006

Molecular cloning and characterization of an invertebrate homologue of a neuropeptide Y receptor

Autor: Kingsley J. A. Cox, Wijnand P. M. Geraerts, H. van Heerikhuizen, R.C. van der Schors, Rob Leurs, Cornelis P. Tensen, Julian F. Burke, E. Vreugdenhil

Publikováno v: European Journal of Neuroscience. 10:3409-3416

Neuropeptide Y is an abundant and physiologically important peptide in vertebrates having effects on food intake, sexual behaviour, blood pressure and circadian rhythms. Neuropeptide Y homologues have been found in invertebrates, where they are very

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::cc02d339dffc9b081e74f247fedb7d89
https://doi.org/10.1046/j.1460-9568.1998.00350.x