Zobrazeno 1 - 10 of 135 pro vyhledávání: '"M. Gåfvels"'
1
Akademický článek
Studies on LXR- and FXR-mediated effects on cholesterol homeostasis in normal and cholic acid-depleted mice
Autor: J. Wang, C. Einarsson, C. Murphy, P. Parini, I. Björkhem, M. Gåfvels, G. Eggertsen
Publikováno v: Journal of Lipid Research, Vol 47, Iss 2, Pp 421-430 (2006)
As previously reported by us, mice with targeted disruption of the CYP8B1 gene (CYP8B1−/−) fail to produce cholic acid (CA), upregulate their bile acid synthesis, reduce the absorption of dietary cholesterol and, after cholesterol feeding, accumu
Externí odkaz: https://doaj.org/article/f5a1c6345c7e4b03b9979304700dc205
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2
LXRβ activation increases intestinal cholesterol absorption, leading to an atherogenic lipoprotein profile
Autor: X, Hu, K R, Steffensen, Z-Y, Jiang, P, Parini, J-Å, Gustafsson, M, Gåfvels, G, Eggertsen
Publikováno v: Journal of internal medicine. 272(5)
Liver X receptors (LXRs) are essential for the regulation of intestinal cholesterol absorption. Because two isoforms exist, LXRα and LXRβ, with overlapping but not identical functions, we investigated whether LXRα and LXRβ exert different effects
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::5ae209ceaaa3cd1bea0e6d9ecade1cc0
https://pubmed.ncbi.nlm.nih.gov/22651910
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3
Characterization of two novel mutations in the glucocorticoid receptor gene in patients with primary cortisol resistance
Autor: M, Ruiz, U, Lind, M, Gåfvels, G, Eggertsen, J, Carlstedt-Duke, L, Nilsson, M, Holtmann, P, Stierna, A C, Wikström, S, Werner
Publikováno v: Clinical endocrinology. 55(3)
Primary glucocorticoid resistance is characterized by decreased sensitivity to cortisol signalling. We have performed genetic analysis of the glucocorticoid receptor (GR) gene in 12 unrelated patients with primary cortisol resistance as defined by a
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::2b52aca1d157be15ef97e71bf63cf7d9
https://pubmed.ncbi.nlm.nih.gov/11589680
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4
Lipoprotein receptors in acute myelogenous leukemia: failure to detect increased low-density lipoprotein (LDL) receptor numbers in cell membranes despite increased cellular LDL degradation
Autor: M, Rudling, M, Gåfvels, P, Parini, G, Gahrton, B, Angelin
Publikováno v: The American journal of pathology. 153(6)
The high-affinity degradation of low-density lipoprotein (LDL) is enhanced 3- to 100-fold in leukemic blood cells from patients with acute myelogenous leukemia (AML), suggesting an increased cellular LDL receptor expression. There are, however, incon
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::225e4464c1470ce93a4f74631d8cc885
https://pubmed.ncbi.nlm.nih.gov/9846982
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5
Degradation of urokinase plasminogen activator (UPA) in endometrial stromal cells requires both the UPA receptor and the low-density lipoprotein receptor-related protein/alpha2-macroglobulin receptor
Autor: Bertil Casslén, B Angelin, B Gustavsson, M Gåfvels
Publikováno v: Molecular human reproduction. 4(6)
Primary cultures of human endometrial stromal cells expressed a single class of specific high-affinity binding sites for urokinase plasminogen activator (UPA) with a dissociation constant KD 1.0 nmol/l and saturation at 2.0 nmol/l. Similar binding da
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bb012e8dbaea625e90dbbaf63c9e1e44
https://pubmed.ncbi.nlm.nih.gov/9665342
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6
Epidermal growth factor receptor gene expression and binding capacity in renal cell carcinoma, in relation to tumor stage, grade and DNA ploidy
Autor: J.-E. Damber, M. Gåfvels, Börje Ljungberg
Publikováno v: Urological research. 22(5)
Epidermal growth factor receptor (EGFr) was studied in 19 renal cell carcinomas using competitive binding analysis and solution hybridization sssay. EGFr binding capacity and EGFr mRNA expression were significantly higher in tumors in comparison with
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9f39f2907576000830bdca2379c292ae
https://pubmed.ncbi.nlm.nih.gov/7879316
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8
Localized increases in ovarian vascular permeability and leucocyte accumulation after induced ovulation in rabbits
Autor: U. Gerdes, Anders Bergh, S. Cajander, M. Gåfvels
Publikováno v: Journal of reproduction and fertility. 95(2)
Colloidal carbon was injected i.v. in mature virgin rabbits at different times after induction of ovulation by human chorionic gonadotrophin (hCG, 100 iu) or mating. Before induction of ovulation, slight carbon leakage was observed in the inner vascu
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::74b5fe8b02683901d11da8b78c069049
https://pubmed.ncbi.nlm.nih.gov/1518008
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9
Expression of lipoprotein lipase in ovaries of the guinea pig
Autor: L, Camps, M, Gåfvels, M, Reina, C, Wallin, S, Vilaró, T, Olivecrona
Publikováno v: Biology of reproduction. 42(5-6)
Guinea pig ovaries were found to have significant lipoprotein lipase (LPL) activity, corresponding to almost one-tenth the activity in paraovarian adipose tissue and in heart per gram of tissue. Northern blot analysis demonstrated the same three spec
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::85fd512f9f3e01c8ff6018a9be2a298b
https://pubmed.ncbi.nlm.nih.gov/2383615
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10
Akademický článek
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