Zobrazeno 1 - 10 of 263 pro vyhledávání: '"M. GRIFANTINI"'
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Tiazofurine ICN Pharmaceuticals
Autor: M, Grifantini
Publikováno v: Current opinion in investigational drugs (London, England : 2000). 1(2)
Tiazofurine is a nucleoside analog with oncolytic activity being developed by Ribapharm (formerly ICN Pharmaceuticals) as a potential treatment for leukemia. It is metabolized to TAD (thiazole-4-carboxamide adenine dinucleotide), an inhibitor of IMP
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::54c7a34f13c83612f81c3c6e076d2735
https://pubmed.ncbi.nlm.nih.gov/11249583
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4
A new C-nucleoside analogue of tiazofurin: synthesis and biological evaluation of 2-beta-D-ribofuranosylimidazole-4-carboxamide (imidazofurin)
Autor: P, Franchetti, S, Marchetti, L, Cappellacci, J A, Yalowitz, H N, Jayaram, B M, Goldstein, M, Grifantini
Publikováno v: Bioorganicmedicinal chemistry letters. 11(1)
2-Beta-D-ribofuranosylimidazole-4-carboxamide, an imidazole analogue of the antitumor agent tiazofurin, was synthesized and evaluated for the growth inhibitory activity of human myelogenous leukemia K562 cells.
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::bef83bf48d5b1535d6e6a1eb5f3b6fe7
https://pubmed.ncbi.nlm.nih.gov/11140736
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5
Potent and selective inhibitors of human immunodeficiency virus protease structurally related to L-694,746
Autor: P, Franchetti, P, Perlini, G, Abu Sheikha, L, Cappellacci, M, Grifantini, A G, Loi, A, De Montis, A, Pani, M E, Marongiu, P, La Colla
Publikováno v: Antiviral chemistrychemotherapy. 9(4)
A series of human immunodeficiency virus (HIV) protease inhibitors, which are analogues of N-[2(R)-hydroxy-1(S)- indanyl]-5(S)-[(tert-butyloxycarbonyl)amino]-4(S)-hydroxy-6-phenyl-2-(R) - [[4-(carboxymethoxy)phenyl]methyl]hexanamide (L-694,746), a me
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::f8bd43fef900af257319ce9319b71799
https://pubmed.ncbi.nlm.nih.gov/9875409
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7
Enhancement of the anti-HIV-1 activity of ddAdo by coformycin, EHNA and deaza-EHNA derivatives
Autor: M E, Marongiu, A, Pani, E, Tinti, M, Grifantini, P, Franchetti, G, Cristalli, P, La Colla
Publikováno v: The new microbiologica. 18(4)
2',3'-dideoxyadenosine (ddAdo) and 2',3'-dideoxyinosine (ddIno) are potent and selective inhibitors of the replication of the human immunodeficiency virus type 1 (HIV1) in several cell culture systems. Equipotent in terms of antiviral activity, both
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::4906c9cc6ec8f3dfb52ae9580d3eddc8
https://pubmed.ncbi.nlm.nih.gov/8590388
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