Zobrazeno 1 - 10
of 27
pro vyhledávání: '"M. G. Spillantini"'
Publikováno v:
Cell Transplantation, Vol 16 (2007)
α-Synuclein is thought to play an important role in the pathology of Parkinson's disease (PD). Truncated forms of this protein can be found in PD brain extracts, and these species aggregate faster and are more susceptible to oxidative stress than th
Externí odkaz:
https://doaj.org/article/c04560579e20431992c9023b5b46dbe8
Autor:
G. Partsch, Marco Matucci-Cerinic, M. G. Spillantini, Gigliola Leoncini, L. Sacerdoti, A. Lombardi, Alberto Moggi Pignone
Publikováno v:
Rheumatology International. 13:1-4
In recent years the role of the peripheral nervous system has been focused on the pathogenesis of rheumatoid arthritis (RA). In particular, substance P (SP), released by the sensory terminals, has been demonstrated to be involved in cartilage breakdo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1f67b31a73e1c97165495843c2966db3
https://doi.org/10.1007/bf00290326
https://doi.org/10.1007/bf00290326
Publikováno v:
DNA Sequence. 2:211-218
The rat glutamate receptor is a 907 amino acid transmembrane protein. Using the rat GluR1 cDNA as a probe, we have isolated cDNA clones from a human hippocampal cDNA library. Sequence of a full length cDNA clone revealed 98.2% and 89.4% identity to t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3c0c3f0bfa12efb16447913404d8b6b1
https://doi.org/10.3109/10425179209020805
https://doi.org/10.3109/10425179209020805
Autor:
A C, Bruni, T, Kawarai, M G, Spillantini, P H, St-George Hyslop, A, Leotta, S, Lio, J-F, Foncin, K H, El Hachimi
Publikováno v:
Revue neurologique. 160(12)
Fronto-temporal dementias (FTD) were described a century ago on the macroscopic basis of frontal and/or temporal lobe atrophy. Progress in neuropathology, immunohistochemistry, biochemistry and genetics has since shown that they are heterogeneous ent
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::f5d22184fcc25bf0f9d21db4cc5b5056
https://pubmed.ncbi.nlm.nih.gov/15602363
https://pubmed.ncbi.nlm.nih.gov/15602363
Autor:
M G, Spillantini, M, Goedert
Publikováno v:
Advances in experimental medicine and biology. 487
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::71db02d10963e75a50ce9c80656f8c91
https://pubmed.ncbi.nlm.nih.gov/11403160
https://pubmed.ncbi.nlm.nih.gov/11403160
Autor:
M, Yasuda, J, Takamatsu, I, D'Souza, R A, Crowther, T, Kawamata, M, Hasegawa, H, Hasegawa, M G, Spillantini, S, Tanimukai, P, Poorkaj, L, Varani, G, Varani, T, Iwatsubo, M, Goedert, D G, Schellenberg, C, Tanaka
Publikováno v:
Annals of neurology. 47(4)
Exonic and intronic mutations in the tau gene cause familial frontotemporal dementia and parkinsonism linked to chromosome 17. Here, we describe a new mutation, consisting of a C-to-T transition at position +12 of the intron following exon 10 of the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::f147e76c4921f99d04b5f7e8abc689d8
https://pubmed.ncbi.nlm.nih.gov/10762149
https://pubmed.ncbi.nlm.nih.gov/10762149
Autor:
M. G. Spillantini, M. Goedert
Publikováno v:
Fatal Attractions: Protein Aggregates in Neurodegenerative Disorders ISBN: 9783642086496
Alzheimer’s disease and Parkinson’s disease are the most common neurodegenerative diseases of the human brain. They are characterized by the presence of ordered filamentous assemblies that gradually develop in a small number of types of nerve cel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::afd66f3c53d400648dea3653aaa85bf9
https://doi.org/10.1007/978-3-662-04056-0_6
https://doi.org/10.1007/978-3-662-04056-0_6
Autor:
J C, van Swieten, M, Stevens, S M, Rosso, P, Rizzu, M, Joosse, I, de Koning, W, Kamphorst, R, Ravid, M G, Spillantini, Niermeijer, P, Heutink
Publikováno v:
Annals of neurology. 46(4)
Several mutations in the tau gene have been found in families with hereditary frontotemporal dementia and parkinsonism linked to chromosome 17q21-22 (FTDP-17). This study is the first attempt to correlate genotype and phenotype in six families with F
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::92511f66ecb040d8b607c49242c13776
https://pubmed.ncbi.nlm.nih.gov/10514099
https://pubmed.ncbi.nlm.nih.gov/10514099
Autor:
M. G. Spillantini, Kathleen A. Welsh-Bohmer, A. D. Roses, Donald E. Schmechel, Christine M. Hulette, R. A. Crowther, P. C. Gaskell, Margaret A. Pericak-Vance, Larry H. Yamaoka
Publikováno v:
Journal of neuropathology and experimental neurology. 58(8)
Frontotemporal dementia with parkinsonism (FTDP-17) is an autosomal dominant disorder that presents clinically with dementia, extrapyramidal signs, and behavioral disturbances in mid-life and progresses to death within 5 to 10 years. Pathologically,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::87957439443c15cb187fd47003414389
https://pubmed.ncbi.nlm.nih.gov/10446810
https://pubmed.ncbi.nlm.nih.gov/10446810
Autor:
M, Hasegawa, A, Cuenda, M G, Spillantini, G M, Thomas, V, Buée-Scherrer, P, Cohen, M, Goedert
Publikováno v:
The Journal of biological chemistry. 274(18)
Mechanisms for selective targeting to unique subcellular sites play an important role in determining the substrate specificities of protein kinases. Here we show that stress-activated protein kinase-3 (SAPK3, also called ERK6 and p38gamma), a member
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::216e08f30f9aa36bc01367028aea2e63
https://pubmed.ncbi.nlm.nih.gov/10212242
https://pubmed.ncbi.nlm.nih.gov/10212242