Zobrazeno 1 - 10
of 49
pro vyhledávání: '"M. G. Santoro"'
Autor:
M G Santoro, A Rossi
Publikováno v:
Biochemical Journal. 308:455-463
Prostaglandins of the A type (PGA) induce the synthesis of 70 kDa heat shock proteins (hsp70) in a large variety of mammalian cells. Induction of hsp70 has been associated with a cytoprotective effect of PGA1 after virus infection or thermal injury.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3f2eca140d7d0cd36ef2cf8451cdea2d
https://doi.org/10.1042/bj3080455
https://doi.org/10.1042/bj3080455
Autor:
M. G. Santoro
Publikováno v:
Experientia. 50:1039-1047
Acute infection of mammalian cells with several types of RNA and DNA viruses often results in induction of heat-shock gene expression. The presence of hsp70 in intact virions, as well as the transient association of HSP with viral proteins and assemb
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d31657c80d12a87a137c541997cd7a20
https://doi.org/10.1007/bf01923459
https://doi.org/10.1007/bf01923459
Autor:
G Elia, M G Santoro
Publikováno v:
Biochemical Journal. 300:201-209
Synthesis of heat-shock proteins (HSPs) is universally induced in eukaryotic and prokaryotic cells by exposure to elevated temperatures or to other types of environmental stress. In mammalian cells, HSPs belonging to the 70 kDa family (HSP70) have a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::350fa62f5ecaa506ff1c055cbd0d03de
https://doi.org/10.1042/bj3000201
https://doi.org/10.1042/bj3000201
Nuclear factor-kappaB (NF-kappaB) is involved in multiple aspects of oncogenesis and controls cancer cell survival by promoting anti-apoptotic gene expression. The constitutive activation of NF-kappaB in several types of cancers, including hematologi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4219ef07ddac8211bcb904feb658514a
http://hdl.handle.net/2318/131269
http://hdl.handle.net/2318/131269
Autor:
Isabella Faraoni, Antonella Puglianiello, Giulia Lanzilli, C D'Onofrio, Carla Amici, Enzo Bonmassar, M. G. Santoro
Publikováno v:
International Journal of Cancer. 51:481-488
Prostaglandin (PG) A and J exert anti-viral and anti-proliferative effects in a number of experimental models. In particular, multiple treatments with PGAs prevent in vitro the clonal selection of HTLV-l-infected and potentially transformed cord-bloo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ff0303bf05a6ccdeecac54fec6ed967e
https://doi.org/10.1002/ijc.2910510324
https://doi.org/10.1002/ijc.2910510324
Autor:
C. Amici, M. G. Santoro
Publikováno v:
Journal of General Virology. 72:1877-1885
The antiviral action of cyclopentenone prostaglandins (PGs) is generally associated with alterations in the synthesis and/or maturation of specific virus proteins. In particular, inhibition of Sendai virus (SV) replication in African green monkey kid
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fa5560bd050ac011b795a69414b1bb4d
https://doi.org/10.1099/0022-1317-72-8-1877
https://doi.org/10.1099/0022-1317-72-8-1877
Publikováno v:
British Journal of Cancer
Type A prostaglandins (PGA1 and 16,16-dimethyl-PGA2-methyl ester) were found to block the proliferation of HTLV-I infected cord blood lymphocytes (CBL) in vitro, thus preventing the clonal immortalisation that is considered as a predisposing conditio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::99b5cf330a3ad2bb86863e4b37cac5ca
http://europepmc.org/articles/PMC1971418
http://europepmc.org/articles/PMC1971418
Nuclear factor-kappaB (NF-kappaB), a transcription factor with a critical role in promoting inflammation and cell survival, is constitutively activated in estrogen-receptor (ER)-negative breast cancer and is considered a potential therapeutic target
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::352b94dc4262a37bf396fdec77feca33
http://hdl.handle.net/2318/22603
http://hdl.handle.net/2318/22603
Publikováno v:
The Journal of biological chemistry. 276(31)
Herpes simplex viruses (HSV) are ubiquitous pathogens causing a variety of diseases ranging from mild illness to severe life-threatening infections. HSV utilize cellular signaling pathways and transcription factors to promote their replication. Here
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::a4bb6a14e59da08716ad31e488d9370f
https://pubmed.ncbi.nlm.nih.gov/11387335
https://pubmed.ncbi.nlm.nih.gov/11387335
Autor:
Richard I. Morimoto, M G Santoro
Publikováno v:
Nature biotechnology. 16(9)
Molecular chaperones protect proteins against environmental and physiologic stress and from the deleterious consequences of an imbalance in protein homeostasis. Many of these stresses, if prolonged, result in defective development and pathologies ass
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e3b0407de55c6d4ec2bf354d71eb2f2b
https://pubmed.ncbi.nlm.nih.gov/9743115
https://pubmed.ncbi.nlm.nih.gov/9743115