Zobrazeno 1 - 10 of 41 pro vyhledávání: '"M. G. Rumsby"'
1
A role for protein kinase C subtypes α and ε in phorbol-ester-enhanced K+- and carbachol-evoked noradrenaline release from the human neuroblastoma SH-SY5Y
Autor: Neil A. Turner, M. G. Rumsby, Stephen G. Ball, F. A. Mcmorris, Peter F. T. Vaughan, J. H. Walker
Publikováno v: Biochemical Journal. 297:407-413
Protein kinase C (PKC) consists of a family of closely related subtypes which differ in their localization and activation properties. Our previous studies have suggested a role for PKC in the regulation of noradrenaline (NA) release from the human ne
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a1a9b5fc98582470ceb452460caec522
https://doi.org/10.1042/bj2970407
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2
Protein kinases and multidrug resistance
Autor: M G, Rumsby, L, Drew, J R, Warr
Publikováno v: Cytotechnology. 27(1-3)
The role of protein kinases in the multidrug resistance phenotype of cancer cell lines is discussed with an emphasis on protein kinase C and protein kinase A. Evidence that P-glycoprotein is phosphorylated by these kinases is summarised and the relat
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::dc18b2522b87c75ecf210bda7521477f
https://pubmed.ncbi.nlm.nih.gov/19002793
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3
Changes in protein kinase C epsilon phosphorylation status and intracellular localization as 3T3 and 3T6 fibroblasts grow to confluency and quiescence: a role for phosphorylation at ser-729?
Autor: K, England, M G, Rumsby
Publikováno v: The Biochemical journal.
Protein kinase C (PKC) epsilon in 3T3 and 3T6 fibroblasts and in C6 glioma cells migrated on SDS/PAGE predominantly as a doublet with molecular masses of 87 and 95 kDa (PKC epsilon(87) and PKC epsilon(95) respectively). PKC epsilon(95) predominates w
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::b943d540c72640fdac2a695ecb5d7097
https://pubmed.ncbi.nlm.nih.gov/11062054
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4
Phage display identifies thioredoxin and superoxide dismutase as novel protein kinase C-interacting proteins: thioredoxin inhibits protein kinase C-mediated phosphorylation of histone
Autor: J A, Watson, M G, Rumsby, R G, Wolowacz
Publikováno v: The Biochemical journal.
Using phage display we identify the redox proteins thioredoxin and superoxide dismutase (SOD) as novel protein kinase C (PKC)-interacting proteins. Overlay assays demonstrated that PKC bound to immobilized thioredoxin, providing supporting evidence f
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::7a0430848ef5f3c63d4041148005fa19
https://pubmed.ncbi.nlm.nih.gov/10510292
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5
Changes in protein kinase C subspecies protein expression and activity in a series of multidrug-resistant human KB carcinoma cell lines
Autor: L, Drew, N, Groome, T J, Hallam, J R, Warr, M G, Rumsby
Publikováno v: Oncology research. 6(9)
We have investigated the relationship between protein kinase C (PKC), levels of resistance and drug used for selection in a series of human KB carcinoma cell lines by comparing protein kinase C activity and PKC alpha, beta I, beta II, gamma, delta, e
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::22f536c1db086ae6a07049032338f7f1
https://pubmed.ncbi.nlm.nih.gov/7703529
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6
Lipid biosynthesis by chloroplasts isolated from developing Zea mays
Autor: M. G. Rumsby, J. C. Hawke, Rachel M. Leech
Publikováno v: Phytochemistry. 13:403-413
Fatty acid biosynthesis by isolated plastids has been examined in relation to chloroplast development and differentiation in leaves of maize plants grown in light for 7 days. Biosynthesis of fatty acids from acetate by proplastids prepared from the b
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::6467264b9e25ccf188442d66aaf890f3
https://doi.org/10.1016/s0031-9422(00)91224-x
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7
Localization of sites for ionic interaction with lipid in the C-terminal third of the bovine myelin basic protein
Autor: M G Rumsby, A J S Jones
Publikováno v: Biochemical Journal. 167:583-591
The myelin basic protein from bovine brain tissue was purified and the two peptides obtained by cleavage of the polypeptide chain at the single tryptophan residue were isolated. The interaction of these peptides and the intact basic protein with comp
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f65668f3c63de9312a40b2d4cf373ffa
https://doi.org/10.1042/bj1670583
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8
The intrinsic fluorescence of isolated central-nervous-system myelin-sheath preparations
Autor: A J Crang, M G Rumsby
Publikováno v: Biochemical Journal. 177:739-745
The intrinsic fluorescence characteristics of tyrosine and tryptophan residues in the proteins of isolated central-nervous-system myelin were investigated to gain information concerning the location of these residues within the intact membrane system
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::92cdccc793e942423f4ff1e16fe1222a
https://doi.org/10.1042/bj1770739
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10
Studies on rumen metabolism. V.—formation of branched long chain fatty acids in cultures of rumen bacteria
Autor: M. G. Rumsby, J. C. Hawke, J. W. Tweedie
Publikováno v: Journal of the Science of Food and Agriculture. 17:241-244
When mixed rumen bacteria were incubated with isobutyrate-1-14C, the 14C-label was incorporated into branched long chain fatty acids with both odd and even numbers of carbon atoms. Tracer studies showed that the 14C-label from DL-valine-4-14C was inc
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::59e24dcd5037ac51c3ead93de0885130
https://doi.org/10.1002/jsfa.2740170603
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