Zobrazeno 1 - 8
of 8
pro vyhledávání: '"M. G. Lyman"'
Publikováno v:
mBio, Vol 3, Iss 2 (2012)
ABSTRACT Pseudorabies virus (PRV), an alphaherpesvirus with a broad host range, replicates and spreads in chains of synaptically connected neurons. The PRV protein Us9 is a small membrane protein that is highly conserved among alphaherpesviruses and
Externí odkaz:
https://doaj.org/article/409daa9887be42a39896df1e90fff469
Publikováno v:
Journal of Virology. 83:1173-1183
The attenuated pseudorabies virus (PRV) strain Bartha contains several characterized mutations that affect its virulence and ability to spread through neural circuits. This strain contains a small genomic deletion that abrogates anterograde spread an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::84cb16feb3de4266932cfb3c5333ac8c
https://doi.org/10.1128/jvi.02102-08
https://doi.org/10.1128/jvi.02102-08
Publikováno v:
Journal of Virology. 82:10308-10311
Pseudorabies virus encodes a membrane protein (Us9) that is essential for the axonal sorting of virus particles within neurons and anterograde spread in the mammalian nervous system. Enhanced green fluorescent protein (GFP)-tagged Us9 mimicked the tr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ca3e8c11ce8757ecb4e4bb8d23b41074
https://doi.org/10.1128/jvi.01204-08
https://doi.org/10.1128/jvi.01204-08
Publikováno v:
Journal of Virology. 81:11363-11371
Pseudorabies virus (PRV) mutants lacking the Us9 gene cannot spread from presynaptic to postsynaptic neurons in the rat visual system, although retrograde spread remains unaffected. We sought to recapitulate these findings in vitro using the isolator
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ef3c4acd69b4eb1e4f2afa4f0fe33bf6
https://doi.org/10.1128/jvi.01281-07
https://doi.org/10.1128/jvi.01281-07
Publikováno v:
mBio, Vol 3, Iss 2 (2012)
mBio
mBio
Pseudorabies virus (PRV), an alphaherpesvirus with a broad host range, replicates and spreads in chains of synaptically connected neurons. The PRV protein Us9 is a small membrane protein that is highly conserved among alphaherpesviruses and is essent
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7b015ecc5d1fb829485bbd8ca6c6964e
https://journals.asm.org/doi/10.1128/mBio.00063-12
https://journals.asm.org/doi/10.1128/mBio.00063-12
Publikováno v:
Journal of virology. 83(14)
Pseudorabies virus (PRV) Us9 is a small, tail-anchored (TA) membrane protein that is essential for axonal sorting of viral structural proteins and is highly conserved among other members of the alphaherpesvirus subfamily. We cloned the Us9 homologs f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a369eee5d6338d49ffe4d9e55ec50edc
https://pubmed.ncbi.nlm.nih.gov/19420087
https://pubmed.ncbi.nlm.nih.gov/19420087
Autor:
M. G. Lyman, Lynn W. Enquist
Publikováno v:
Journal of virology. 83(5)
Cellular infrastructure is often compared to a highly organized city. Organelles act as molecular factories to produce proteins, lipids, nucleic acids and energy (ATP). The distribution of these products throughout the cell is critical to cell viabil
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::52580d46a81f23abb3f782c75c109e6c
https://pubmed.ncbi.nlm.nih.gov/18842724
https://pubmed.ncbi.nlm.nih.gov/18842724
Publikováno v:
PLoS Pathogens, Vol 4, Iss 5, p e1000065 (2008)
PLoS Pathogens
PLoS Pathogens
The pseudorabies virus (PRV) Us9 protein plays a central role in targeting viral capsids and glycoproteins to axons of dissociated sympathetic neurons. As a result, Us9 null mutants are defective in anterograde transmission of infection in vivo. Howe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c0d75286985a79afb463e62491c63673
https://doi.org/10.1371/journal.ppat.1000065
https://doi.org/10.1371/journal.ppat.1000065