Výsledky vyhledávání - "M. G. Cimini"

Cardiovascular effects of the K-ATP channel blocker U-37883A and structurally related morpholinoguanidines

Autor: S J, Humphrey, M P, Smith, M G, Cimini, L V, Buchanan, J K, Gibson, S A, Khan, K D, Meisheri

Publikováno v: Methods and findings in experimental and clinical pharmacology. 18(4)

The cardiovascular effects of the K-ATP channel blocker U-37883A and 5 related morpholinoguanidines were determined in 6 experimental preparations. In anesthetized dogs, U-37883A (0.5-8.0 mg/kg i.v.) increased mean arterial pressure (MAP; +18%) and l

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::21e2c9a14a2c39649c21ace13cbb7f69
https://pubmed.ncbi.nlm.nih.gov/8803957

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N-[(omega-amino-1-hydroxyalkyl)phenyl]methanesulfonamide derivatives with class III antiarrhythmic activity

Autor: J. K. Gibson, Jackson B. Hester, M. G. Cimini, B. E. West, Louis L. Skaletzky, P. K. Locker, J. K. Sykes, D. E. Emmert, S. C. Perricone

Publikováno v: Journal of medicinal chemistry. 34(1)

N-[4-[4-(Ethylheptylamino)-1-hydroxybutyl]phenyl]methanesulfonamid e, (E)-2-butenedioate (2:1) salt (ibutilide fumarate, 2E), has been found to have Class III antiarrhythmic activity. In an in vitro rabbit heart tissue preparation designed to evaluat

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a9f50c9f1fc13dcdb9c3d033633809b4
https://pubmed.ncbi.nlm.nih.gov/1992131

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