Zobrazeno 1 - 10
of 10
pro vyhledávání: '"M. G. Chambers"'
Publikováno v:
British Journal of Surgery. 88:1029-1036
Background Faecal incontinence affects 1–2 per cent of the adult population. While many patients can be managed successfully with conservative therapy, a small proportion require surgery. Improved imaging techniques and technological advances have
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::00bdb47ea590f16bb69ccb0d5bc23fcc
https://doi.org/10.1046/j.0007-1323.2001.01807.x
https://doi.org/10.1046/j.0007-1323.2001.01807.x
Publikováno v:
Cell Biochemistry and Function. 14:57-61
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::091c020203d86e59da55e710ce41e590
https://doi.org/10.1002/(sici)1099-0844(199603)14:1<57::aid-cbf643>3.3.co
https://doi.org/10.1002/(sici)1099-0844(199603)14:1<57::aid-cbf643>3.3.co
Publikováno v:
Cell Biochemistry and Function. 14:57-61
Up to nine out of 10 male STR/ORT mice develop osteoarthritis (OA) of the medial tibial cartilage at an early age. This has now been shown to be related to changes in the activity and distribution of monoamine oxidase which is related to the metaboli
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bab71fe68bb6b804b7ac0e0da7996211
https://doi.org/10.1002/cbf.643
https://doi.org/10.1002/cbf.643
Publikováno v:
Journal of Orthopaedic Research. 8:101-104
At least 80% of male STR/ORT mice naturally develop osteoarthritis that predominantly affects the medial tibial cartilage. Overt osteoarthritic changes, as judged by radiological and histological abnormalities, become apparent after 30 weeks of age.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0536d9004573a39cfbfd4d315783b551
https://doi.org/10.1002/jor.1100080113
https://doi.org/10.1002/jor.1100080113
Publikováno v:
Arthritis and rheumatism. 44(6)
To map aggrecan cleavage by matrix metalloproteinases (MMPs) and aggrecanases in normal murine tibial articular cartilage (CBA strain) and in the development of spontaneous osteoarthritis (OA) in the STR/ort mouse and to assess the influence of sex h
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::2524ea62457f7114df8be6423c848a04
https://pubmed.ncbi.nlm.nih.gov/11407708
https://pubmed.ncbi.nlm.nih.gov/11407708
Publikováno v:
Cell biochemistry and function. 14(1)
Up to nine out of 10 male STR/ORT mice develop osteoarthritis (OA) of the medial tibial cartilage at an early age. This has now been shown to be related to changes in the activity and distribution of monoamine oxidase which is related to the metaboli
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::0008dbb4a47e3eed646c5dda8468cab6
https://pubmed.ncbi.nlm.nih.gov/8907255
https://pubmed.ncbi.nlm.nih.gov/8907255
Autor:
R J, Benschop, E C, Collins, R J, Darling, B W, Allan, D, Leung, E M, Conner, J, Nelson, B, Gaynor, J, Xu, X-F, Wang, R A, Lynch, B, Li, D, McCarty, E S, Nisenbaum, J L, Oskins, C, Lin, K W, Johnson, M G, Chambers
Publikováno v:
Osteoarthritis and Cartilage. (4):578-585
Summary Objective Investigate a role for calcitonin gene-related peptide (CGRP) in osteoarthritis (OA)-related pain. Design Neutralizing antibodies to CGRP were generated de novo . One of these antibodies, LY2951742, was characterized in vitro and te
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3059a2606039e1ec40214ef7c794648c
Publikováno v:
Agents and actions. 28(1-2)
In assessing the possible efficacy of drugs for the treatment of osteoarthritis (OA), it may be helpful to have a model, in animals, of the early development of the disease prior to the expression of secondary phenomena. It is also necessary that suc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b210634b5e1d482ba6d706554fc12d92
https://pubmed.ncbi.nlm.nih.gov/2782224
https://pubmed.ncbi.nlm.nih.gov/2782224
Publikováno v:
British journal of experimental pathology. 69(6)
A high incidence of natural osteoarthritis of the knee joint is found in male mice of the STR/ORT strain. The condition affects mainly the medial tibial cartilage and by the age of 27 weeks most male mice of this strain show some osteoarthritic chang
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::6a11c2abb8418618849df571b025a39e
https://pubmed.ncbi.nlm.nih.gov/3219287
https://pubmed.ncbi.nlm.nih.gov/3219287
Publikováno v:
Value in Health. (6):A357
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a6c09b5cda8493e597458335e02943e7