Zobrazeno 1 - 10
of 32
pro vyhledávání: '"M. G. Castelli"'
Publikováno v:
Chromatographia. 55:S31-S34
The bioavailability of a novel anticancer drug has been estimated in a cannulated mouse model, in which full pharmacokinetic profiles were obtained from a single animal. After with-drawing serial blood samples from the animal, small volumes of the pl
Publikováno v:
Experimental Mechanics. 36:430-435
An experimental evaluation was conducted at NASA Lewis Research Center to compare and contrast the performance of a newly developed resistance strain gage, the PdCr temperature-compensated wire strain gage, to that of a conventional high-temperature
Autor:
C. Pellizzoni, Maurizio Rocchetti, A. Dubini, M. G. Castelli, D. M. F. Edwards, A. Berardi, Italo Poggesi, H. P. Breuel, M. Strolin Benedetti, E. Frigerio
Publikováno v:
Biopharmaceutics & Drug Disposition. 16:443-460
The pharmacokinetics of reboxetine, a new antidepressant agent, were found to be close to linear in a crossover study comparing administration of single 2, 3, 4, and 5 mg capsule doses in 15 healthy male volunteers, and in the same study the capsules
Autor:
M. Colombo, Franz Oesch, M. Strolin Benedetti, P. Marrari, Michael Arand, P Dostert, M. G. Castelli
Publikováno v:
ResearcherID
The effects of the potent anticonvulsant FCE 26743 ((S)-2-(4-(3-fluorobenzyloxy)benzylamino)propionamide) on monoamine oxidase (MAO) activity were measured in-vitro and ex-vivo using rat tissue homogenates. In-vitro, FCE 26743 showed potent and selec
Publikováno v:
Journal of Antimicrobial Chemotherapy. 34:600-603
Publikováno v:
Xenobiotica. 23:115-121
1. The (13S)-dihydro derivative of idarubicin, (13S)-idarubicinol, is the major urinary metabolite of idarubicin in humans. Idarubicinol epimers were quantified by h.p.l.c. in urine from rats, mice, rabbits, dogs and man after i.v. administration of
Thermomechanical fatigue (TMF) data was generated for a Ti-15V-3Cr-3Al-3Sn (Ti-15-3) material reinforced with SCS-6 silicon carbide fibers for both in-phase and out-of-phase thermomechanical cycling. Significant differences in failure mechanisms and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bd3c73c02b4764e61e5fa71f517e85bc
https://doi.org/10.1520/stp24752s
https://doi.org/10.1520/stp24752s
Publikováno v:
Xenobiotica. 21:473-480
1. The (13S)-dihydro derivative of idarubicin, (13S)-idarubicinol, is the major urinary metabolite of idarubicin in humans. Idarubicinol epimers were quantified by h.p.l.c. in urine from rats, mice, rabbits, dogs and man after i.v. administration of
Autor:
Antonino Suarato, R d’Argy, A Fiorino, A Ghiglieri, Francesco Angelucci, Moreno Zamai, Enrico Frigerio, M. G. Castelli, Valeria R. Caiolfa, Enrico Pesenti, M Farao, M. Gigli, C. Pellizzoni
Publikováno v:
Journal of controlled release : official journal of the Controlled Release Society. 65(1-2)
Camptothecin (CPT) is a potent, antitumour drug acting mainly through inhibition of topoisomerase I during the S-phase of the cell cycle. Despite its impressive antitumour activity, clinical development was halted for unpredictable toxic events. Two
Autor:
Italo Poggesi, R. Battaglia, R. Spinelli, Hackett Am, Benedetti Ms, M. G. Castelli, M. Breda, Philippe Dostert
Publikováno v:
Pharmacological research. 41(2)
Plasma pharmacokinetics, excretion balance and urinary metabolites of methoxymorpholino doxorubicin (MMDX) were investigated in male and female rats and in female dogs after i.v. administration of the 14 C-labelled drug. The mean total recovery of ra