Zobrazeno 1 - 10
of 23
pro vyhledávání: '"M. Fuhry"'
Akademický článek
Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.
K zobrazení výsledku je třeba se přihlásit.
Autor:
Krzysztof Appelt, Melnick Michael J, B.‐W. Wu, L. Musick, Mary Ann M. Fuhry, Reich Siegfried Heinz, Mark J. Pino, Jay F. Davies, Anthony J. Trippe
Publikováno v:
Journal of Medicinal Chemistry. 39:2781-2794
The design, synthesis, and crystallographic analysis of protein-inhibitor complexes is described for a novel series of nonpeptidic HIV protease (HIV Pr)inhibitors. Beginning with a cocrystal structure of a Phe-Pro peptidomimetic bound to the HIV Pr,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c8fb4e29ab3ee5663fc2578cdd634cef
https://doi.org/10.1021/jm960093o
https://doi.org/10.1021/jm960093o
Autor:
Andrew N. Payne, Mary Ann M. Fuhry, Simon E. Ward, Miles S. Congreve, R. A. Robinson, Andrew B. Holmes, Edwin C. Davison
Publikováno v:
ChemInform. 25
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9fd882711db314d6de9ffa750c7d1d3f
https://doi.org/10.1002/chin.199406101
https://doi.org/10.1002/chin.199406101
Publikováno v:
ChemInform. 25
Thermal elimination/Claisen rearrangement of selenoxides derived from the enantiomerically pure phenylselenomethyl-substituted cyclic acetals 4 and 8 proceeds stereospecifically to provide the homochiral 8- and 7-membered lactones 5 and 9 respectivel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::75c39de0631f060692858eeddc2ee58b
https://doi.org/10.1002/chin.199408237
https://doi.org/10.1002/chin.199408237
Autor:
B.‐W. Wu, Reich Siegfried Heinz, Melnick Michael J, Anthony J. Trippe, Jay F. Davies, L. Musick, Mary Ann M. Fuhry, Krzysztof Appelt, Mark J. Pino
Publikováno v:
ChemInform. 27
The design, synthesis, and crystallographic analysis of protein−inhibitor complexes is described for a novel series of nonpeptidic HIV protease (HIV Pr) inhibitors. Beginning with a cocrystal structure of a Phe-Pro peptidomimetic bound to the HIV P
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2ca3482018cf683dac9bf7dcf617aac7
https://doi.org/10.1002/chin.199643072
https://doi.org/10.1002/chin.199643072
Autor:
Andrew B. Holmes, Mary Ann M. Fuhry, John E. Davies, Neil Feeder, David R. Marshall, Wilm Buhr, Justin R. Harrison, Jonathan W. Burton, Paul T. O'Sullivan
Publikováno v:
Journal of the American Chemical Society. 126(7)
The total synthesis of octalactins A and B has been achieved in 15 steps (longest linear sequence) and 10% overall yield from commercially available materials. Key steps include the Paterson-Aldol reaction for the rapid assembly of the carbonate 46,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::690d1b375fe900d2b8ebd9343afe481b
http://ora.ox.ac.uk/objects/uuid:f9fc0eb7-bc0a-44bd-9c83-cbcf7e1d8df2
http://ora.ox.ac.uk/objects/uuid:f9fc0eb7-bc0a-44bd-9c83-cbcf7e1d8df2
Autor:
Mary Ann M. Fuhry
Publikováno v:
e-EROS Encyclopedia of Reagents for Organic Synthesis
[54655-07-1] C5H9LiSi (MW 104.17) InChI = 1S/C5H9Si.Li/c1-5-6(2,3)4;/h2-4H3; InChIKey = ZVXXEONXFWSCIZ-UHFFFAOYSA-N (synthesis of unsymmetrically disubstituted alkynes, where use of the silyl protecting group ensures selective monofunctionalization o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6f8745bc66165d9444bc890f5129fbab
https://doi.org/10.1002/047084289x.rl150
https://doi.org/10.1002/047084289x.rl150
Publikováno v:
Cytogenetics and cell genetics. 75(2-3)
We have cloned the cDNA for the human homolog of the rat AP17 gene, a small chain of the clathrin-associated protein complex AP-2. The cDNA is highly conserved between rat and human. Human AP17, gene symbol CLAPS2 (clathrin-associated/assembly/adapto
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6749f2b2134f9d63e44942cafe44821e
https://pubmed.ncbi.nlm.nih.gov/9040778
https://pubmed.ncbi.nlm.nih.gov/9040778
Autor:
Mary Ann M. Fuhry, K. K. Lewis, J F Davies nd, D Nguyen, Melnick Michael J, Anthony J. Trippe, Reich Siegfried Heinz, H. Dawson, Mark J. Pino, Krzysztof Appelt
A class of potent nonpeptidic inhibitors of human immunodeficiency virus protease has been designed by using the three-dimensional structure of the enzyme as a guide. By employing iterative protein cocrystal structure analysis, design, and synthesis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b05197d8c5be39f4cdf78cbb175ee46a
https://europepmc.org/articles/PMC42153/
https://europepmc.org/articles/PMC42153/