Zobrazeno 1 - 10
of 526
pro vyhledávání: '"M. Frydman"'
Publikováno v:
mSystems, Vol 8, Iss 2 (2023)
ABSTRACT The dynamic structures of microbial communities emerge from the complex network of interactions between their constituent microorganisms. Quantitative measurements of these interactions are important for understanding and engineering ecosyst
Externí odkaz:
https://doaj.org/article/3cc8599d46c9491aae531ba209231971
Autor:
Derek Duckett, Mingxiang Teng, William R. Roush, Patricia McDonald, Andrii Monastyrskyi, Wayne Grant, Samer S. Sansil, Sylvia M. Frydman, Massimiliano Aceti, Victor Quereda, Ainhoa Nieto, Simon Bayle, Francesca Vena
Supplementary figures 1 through 8.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::113aa500a3a4f7ca607e96731e874160
https://doi.org/10.1158/1535-7163.22521363
https://doi.org/10.1158/1535-7163.22521363
Autor:
Derek Duckett, Mingxiang Teng, William R. Roush, Patricia McDonald, Andrii Monastyrskyi, Wayne Grant, Samer S. Sansil, Sylvia M. Frydman, Massimiliano Aceti, Victor Quereda, Ainhoa Nieto, Simon Bayle, Francesca Vena
Supplementary Table 1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::57f882c99f372cdc104824caa74b6249
https://doi.org/10.1158/1535-7163.22521360
https://doi.org/10.1158/1535-7163.22521360
Publikováno v:
mBio, Vol 9, Iss 3 (2018)
ABSTRACT Mosquito-transmitted viruses are spread globally and present a great risk to human health. Among the many approaches investigated to limit the diseases caused by these viruses are attempts to make mosquitos resistant to virus infection. Coin
Externí odkaz:
https://doaj.org/article/f380826ae58d437db671d89c1ad40da0
Autor:
Derek R. Duckett, Zhen Wang, Vincent C. Luca, Haitao Ji, Sylvia M Frydman, Min Zhang, Victor Quereda, Qianqian Ming
Publikováno v:
J Med Chem
Aberrant activation of Wnt/β-catenin signaling is strongly associated with many diseases including cancer invasion and metastasis. Small-molecule targeting of the central signaling node of this pathway, β-catenin, is a biologically rational approac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7832b3ba5fe30df4167ce34aa1f59a7b
https://doi.org/10.1021/acs.jmedchem.1c00742
https://doi.org/10.1021/acs.jmedchem.1c00742
Autor:
Rama K. Simhadri, Eva M. Fast, Rong Guo, Michaela J. Schultz, Natalie Vaisman, Luis Ortiz, Joanna Bybee, Barton E. Slatko, Horacio M. Frydman
Publikováno v:
mSphere, Vol 2, Iss 5 (2017)
ABSTRACT Endosymbiotic Wolbachia bacteria and the gut microbiome have independently been shown to affect several aspects of insect biology, including reproduction, development, life span, stem cell activity, and resistance to human pathogens, in inse
Externí odkaz:
https://doaj.org/article/e5a766ae78bf4e3db960a9172d154811
Autor:
Simon Bayle, Victor Quereda, Andrii Monastyrskyi, Derek R. Duckett, Massimilliano Aceti, Sylvia M Frydman, Ainhoa Nieto, Wayne Grant, Samer S. Sansil, Patricia McDonald, Mingxiang Teng, Francesca Vena, William R. Roush
Publikováno v:
Mol Cancer Ther
Although gemcitabine is the cornerstone of care for pancreatic ductal adenocarcinoma (PDA), patients lack durable responses and relapse is inevitable. While the underlying mechanisms leading to gemcitabine resistance are likely to be multifactorial,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::138ea346546ad12a7e8190ad54a2f0de
https://doi.org/10.1158/1535-7163.mct-19-0997
https://doi.org/10.1158/1535-7163.mct-19-0997
Autor:
Michelle E Toomey, Horacio M Frydman
Publikováno v:
PLoS Pathogens, Vol 10, Iss 12, p e1004577 (2014)
Microbial tropism, the infection of specific cells and tissues by a microorganism, is a fundamental aspect of host-microbe interactions. The intracellular bacteria Wolbachia have a peculiar tropism for the stem cell niches in the Drosophila ovary, th
Externí odkaz:
https://doaj.org/article/3d1bdb6fc9fa4b29b7e77793d472872a
Autor:
Horacio M. Frydman, Emilie Lefoulon, Jeremy M. Foster, Luo Sun, Lise Voland, Natalie Vaisman, Barton E. Slatko
Publikováno v:
Scientific Reports, Vol 9, Iss 1, Pp 1-10 (2019)
Scientific Reports
Scientific Reports
Symbiosis is a major force of evolutionary change, influencing virtually all aspects of biology, from population ecology and evolution to genomics and molecular/biochemical mechanisms of development and reproduction. A remarkable example is Wolbachia
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::335c21d57a3e675c8f479cbf56fd7de8
http://link.springer.com/article/10.1038/s41598-019-42454-w
http://link.springer.com/article/10.1038/s41598-019-42454-w
Publikováno v:
mBio, Vol 12, Iss 1 (2021)
Autophagy is an intracellular degradation pathway involved in innate immunity. Pathogenic bacteria have evolved several mechanisms to escape degradation or exploit autophagy to acquire host nutrients. In the case of endosymbionts, which often have co
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8549b11ec0f95fd4912c08a46ca90c2c
https://journals.asm.org/doi/10.1128/mBio.02205-20
https://journals.asm.org/doi/10.1128/mBio.02205-20