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Publikováno v:
Annals of Oncology. 8:101-104
Autor:
M Fizzotti, F Lo Coco, Giuliana Alimena, C Quartarone, Franco Mandelli, Pier Giuseppe Pelicci, Simona Pisegna, Giuseppe Cimino
Publikováno v:
Scopus-Elsevier
A recently described putative tumor suppressor gene, the cyclin-dependent kinase 4 inhibitor (p16), has been shown to be altered by deletions and/or point mutations in various human cancers. To assess the incidence and clinico-biologic correlations o
Autor:
Massimo Aglietta, Antonio Capaldi, M. Fizzotti, A.R. Bucci, Fabrizio Carnevale-Schianca, A. Ricchiardi, Giovanni Grignani, D. Rota-scalabrini, S. Aliberti
The existence of a graft versus tumor (GVT) effect of donor-derived T cells after allogeneic hematopoietic stem cell transplantation is well established as a critical component for the success of the procedure in several hematologic malignancies. Alt
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::06221c3e8cc7e654acb2d078352f40fa
http://hdl.handle.net/2318/30687
http://hdl.handle.net/2318/30687
Autor:
B, Falini, K, Pulford, A, Pucciarini, A, Carbone, C, De Wolf-Peeters, J, Cordell, M, Fizzotti, A, Santucci, P G, Pelicci, S, Pileri, E, Campo, G, Ott, G, Delsol, D Y, Mason
Publikováno v:
Blood. 94(10)
The tumor cells in ALK-positive lymphoma ("ALKoma") usually express the product of the NPM-ALK chimeric gene, generated by the t(2;5) chromosomal translocation. However, 10% to 20% of ALK-positive lymphomas express ALK fusion protein(s) other than NP
Autor:
B, Falini, S, Pileri, P L, Zinzani, A, Carbone, V, Zagonel, C, Wolf-Peeters, G, Verhoef, F, Menestrina, G, Todeschini, M, Paulli, M, Lazzarino, R, Giardini, A, Aiello, H D, Foss, I, Araujo, M, Fizzotti, P G, Pelicci, L, Flenghi, M F, Martelli, A, Santucci
Publikováno v:
Blood. 93(8)
A distinct pathologic entity (ALK+ lymphoma) that is characterized by expression of the anaplastic lymphoma kinase (ALK) protein has recently emerged within the heterogeneous group of CD30(+) anaplastic large-cell lymphomas. Information on clinical f
The human bcl-6 gene, which is rearranged in about 30% of diffuse large B-cell lymphomas (DLCL-B), encodes for a Kruppel-type zinc finger protein of 706 amino acids. In order to investigate the expression of the bcl-6 gene at the protein level, two m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::46097be17cc4257a53635449090e32ef
http://hdl.handle.net/11391/175926
http://hdl.handle.net/11391/175926
Publikováno v:
Cancer research. 56(23)
Replication errors (RERs) at microsatellite loci were examined in 46 specimens of nonfamilial colorectal cancer. Somatic microsatellite alterations in at least two genetic loci, D11S904, D13S175, D2S123, and D10S197, consistent with a RER(+) phenotyp
Autor:
S. S. Clark, M. Fizzotti
Publikováno v:
Immunological investigations. 24(3)
The CD45 glycoprotein family exhibits cell-lineage-associated structural heterogeneity which is due, in part, to alternative pre-mRNA splicing. The Abelson murine leukemia (A-MuLV) preferentially transforms immature B cells that express a B-cell-spec
Publikováno v:
Journal of virology. 67(10)
The human BCR-ABL oncogenes encoded by the Philadelphia chromosome (Ph) affect the pathogenesis of diverse types of leukemia and yet are rarely associated with T-lymphoid leukemia. To determine whether BCR-ABL kinases are inefficient in transforming