Zobrazeno 1 - 10
of 251
pro vyhledávání: '"M. Fitzsimmons"'
Autor:
Rebecca C Oettle, Harriet A Dickinson, Colin M Fitzsimmons, Moussa Sacko, Edridah M Tukahebwa, Iain W Chalmers, Shona Wilson
Publikováno v:
PLoS Pathogens, Vol 19, Iss 5, p e1011037 (2023)
Schistosoma haematobium is the most prevalent of the human-infecting schistosome species, causing significant morbidity in endemically exposed populations. Despite this, it has been relatively understudied compared to its fellow species, S. mansoni.
Externí odkaz:
https://doaj.org/article/febe9ce060a24687a3945fbad2a73861
Publikováno v:
PLoS Computational Biology, Vol 17, Iss 6, p e1009057 (2021)
Externí odkaz:
https://doaj.org/article/cc1c4f40d42c4fd58968692f65ae0d40
Autor:
Kale Kundert, James E. Lucas, Kyle E. Watters, Christof Fellmann, Andrew H. Ng, Benjamin M. Heineike, Christina M. Fitzsimmons, Benjamin L. Oakes, Jiuxin Qu, Neha Prasad, Oren S. Rosenberg, David F. Savage, Hana El-Samad, Jennifer A. Doudna, Tanja Kortemme
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-11 (2019)
Control of CRISPR-Cas9 activity allows for fine-tuning of editing and gene expression. Here the authors use gRNAs modified with RNA aptamers to enable small molecule control in bacterial systems.
Externí odkaz:
https://doaj.org/article/75a198d8f2ba47a985055e98863b4ffd
Autor:
Rebecca C. Oettle, Harriet A. Dickinson, Colin M. Fitzsimmons, Moussa Sacko, Edridah M. Tukahebwa, Iain W. Chalmers, Shona Wilson
Schistosoma haematobium is the most prevalent of the human-infecting schistosome species, causing significant morbidity in endemically exposed populations. Despite this, it has been relatively understudied compared to its fellow species, S. mansoni.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bc0ef3be95f5845aa5b03ce9d70bc6aa
https://www.repository.cam.ac.uk/handle/1810/350314
https://www.repository.cam.ac.uk/handle/1810/350314
Autor:
Christina M. Fitzsimmons, Mariana D. Mandler, Judith C. Lunger, Dalen Chan, Siddhardha S. Maligireddy, Alexandra C. Schmiechen, Supuni Thalalla Gamage, Courtney Link, Lisa M. Jenkins, Daniel R. Crooks, Jordan L. Meier, W. Marston Linehan, Pedro J. Batista
Metabolic reprogramming is a hallmark of cancer that facilitates changes in many adaptive biological processes. Mutations in the tricarboxylic acid (TCA) cycle enzyme fumarate hydratase (FH) lead to fumarate accumulation and cause hereditary leiomyom
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4bf2c3915f7b605357eb17693dbf351c
https://doi.org/10.1101/2023.04.10.536262
https://doi.org/10.1101/2023.04.10.536262
Autor:
Rebecca C. Oettle, Harriet A. Dickinson, Colin M. Fitzsimmons, Moussa Sacko, Edridah M. Tukahebwa, Iain W. Chalmers, Shona Wilson
Schistosoma haematobiumis the most prevalent of the human-infecting schistosome species, causing significant morbidity in endemically exposed populations. Despite this, it has been relatively understudied compared to its fellow species,S. mansoni. He
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2a2f6f8d71254e8d87471acadc96d44c
https://doi.org/10.1101/2022.12.02.518813
https://doi.org/10.1101/2022.12.02.518813
Autor:
Robert W. Robey, Christina M. Fitzsimmons, Wilfried M. Guiblet, William J.E. Frye, José M. González Dalmasy, Li Wang, Drake A. Russell, Lyn M. Huff, Andrew J. Perciaccante, Fatima Ali-Rahmani, Crystal C. Lipsey, Heidi M. Wade, Allison V. Mitchell, Siddhardha S. Maligireddy, David Terrero, Donna Butcher, Elijah F. Edmondson, Lisa M. Jenkins, Tatiana Nikitina, Victor B. Zhurkin, Amit K. Tiwari, Anthony D. Piscopio, Rheem A. Totah, Susan E. Bates, H. Efsun Arda, Michael M. Gottesman, Pedro J. Batista
Histone deacetylase inhibitors (HDACis) are part of a growing class of epigenetic therapies used for the treatment of cancer. While elevated levels of the efflux pump P-gp are associated within vitroresistance to romidepsin, this mechanism does not t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0eab6c73a6fa5f6f5baa893e9093b0da
https://doi.org/10.1101/2022.10.07.511310
https://doi.org/10.1101/2022.10.07.511310
Autor:
Carolina Caban Rivera, Chau Do, Emma M. Fitzsimmons, Rachael E. Price, Xiangdang Shi, George M. Smith, Ellen M. Unterwald
Publikováno v:
The FASEB Journal. 36
Autor:
Michael H. Tomasson, Mahmoud Ali, Vanessa De Oliveira, Qian Xiao, Yogesh Jethava, Fenghuang Zhan, Adam M. Fitzsimmons, Melissa L. Bates
Publikováno v:
International Journal of Molecular Sciences, Vol 19, Iss 11, p 3621 (2018)
Multiple myeloma is an invariably fatal cancer of plasma cells. Despite tremendous advances in treatment, this malignancy remains incurable in most individuals. We postulate that strategies aimed at prevention have the potential to be more effective
Externí odkaz:
https://doaj.org/article/bc59ad7c06ab4ff2922011f6e95b476b
Autor:
Siba El Hussein, Andrew G. Evans, John M. Fitzsimmons, Nufatt Leong, Meghan Buldo, Jeremy P. Segal, Audrey N. Jajosky, Paul G. Rothberg, Jane L. Liesveld, Zoltán N. Oltvai
Publikováno v:
Molecular Case Studies. 9:a006241
Autologous and allogeneic hematopoietic stem cell transplantation (HSCT) has revolutionized the therapy of hematolymphoid malignancies. Yet, how to best detect or predict the emergence of HSCT-related complications remain unresolved. Here, we describ