Zobrazeno 1 - 10
of 1 576
pro vyhledávání: '"M. Findlay"'
Autor:
K. Sharples, N. K. Vear, J. Porter-Steele, D. J. Anderson, T. H. Moeke-Maxwell, B. B. Laing, L. Young, T. G. Bailey, S. Benge, Y. Huang, E. Crowley, R. Day, R. Cartwright, M. Findlay, D. Porter, M. Kuper, I. Campbell, A. L. McCarthy
Publikováno v:
Pilot and Feasibility Studies, Vol 8, Iss 1, Pp 1-10 (2022)
Abstract Background Younger women (defined as those < 50 years who are likely pre-menopausal at time of diagnosis) with breast cancer often experience persistent treatment-related side effects that adversely affect their physical and psychological we
Externí odkaz:
https://doaj.org/article/76fa12cfe0ee42958d9321064002181f
Autor:
Nicolas Loyer, Elizabeth KJ Hogg, Hayley G Shaw, Anna Pasztor, David H Murray, Greg M Findlay, Jens Januschke
Publikováno v:
eLife, Vol 13 (2024)
The generation of distinct cell fates during development depends on asymmetric cell division of progenitor cells. In the central and peripheral nervous system of Drosophila, progenitor cells respectively called neuroblasts or sensory organ precursors
Externí odkaz:
https://doaj.org/article/54589dcf729848159a41ff66a90b75e1
Autor:
David M. Findlay, Author
This book opens the door to the frequently obscure world of scientific discovery, not just to document discoveries, but also to explain how these discoveries come about. As an example, it tells, in an accessible way, the exciting story of the importa
Autor:
Francisco Bustos, Carmen Espejo-Serrano, Anna Segarra-Fas, Rachel Toth, Alison J. Eaton, Kristin D. Kernohan, Meredith J. Wilson, Lisa G. Riley, Greg M. Findlay
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-9 (2021)
Abstract Tonne–Kalscheuer syndrome (TOKAS) is an X-linked intellectual disability syndrome associated with variable clinical features including craniofacial abnormalities, hypogenitalism and diaphragmatic hernia. TOKAS is caused exclusively by vari
Externí odkaz:
https://doaj.org/article/2d52100e1cdb40aa897c41b55f0c87e6
Autor:
John M. Findlay, Bruce W. Hevly
Outstanding Title by Choice MagazineOn the banks of the Pacific Northwest's greatest river lies the Hanford nuclear reservation, an industrial site that appears to be at odds with the surrounding vineyards and desert. The 586-square-mile compound on
Autor:
Rosalia Fernandez-Alonso, Francisco Bustos, Manon Budzyk, Pankaj Kumar, Andreas O. Helbig, Jens Hukelmann, Angus I. Lamond, Fredrik Lanner, Houjiang Zhou, Evangelia Petsalaki, Greg M. Findlay
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-13 (2020)
Fgf4 is a critical signal driving embryonic stem cell (ESC) exit from pluripotency and differentiation. Here the authors identify EPHA2 as a target of FGF4 signalling in ESCs, and show that EPHA2-EFNA1 signalling promotes pluripotent gene expression
Externí odkaz:
https://doaj.org/article/df268364679f47c9817b1c300c169406
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 9 (2021)
Protein phosphatases are major regulators of signal transduction and they are involved in key cellular mechanisms such as proliferation, differentiation, and cell survival. Here we focus on one class of protein phosphatases, the type IIA Receptor-typ
Externí odkaz:
https://doaj.org/article/3f84b0848e664cd2819799d5a437fd83
Publikováno v:
BMC Biology, Vol 17, Iss 1, Pp 1-13 (2019)
Abstract Background Recent advances in genome editing have facilitated the direct manipulation of not only the genome, but also the epigenome. Genome editing is typically performed by introducing a single CRISPR/Cas9-mediated double-strand break (DSB
Externí odkaz:
https://doaj.org/article/f1c62c0e368840dca1ea8e83c6c5a8fa
Publikováno v:
Bone Reports, Vol 12, Iss , Pp 100269- (2020)
Introduction: Bone marrow lesions (BMLs) are frequently identified by MRI in the subchondral bone in knee osteoarthritis (KOA). BMLs are known to be closely associated with joint pain, loss of the cartilage and structural changes in the subchondral t
Externí odkaz:
https://doaj.org/article/cb9873f20dc74e30818e0080ee2fc1c9
Autor:
T. P. MacGregor, R. Carter, R. S. Gillies, J. M. Findlay, C. Kartsonaki, F. Castro-Giner, N. Sahgal, L. M. Wang, R. Chetty, N. D. Maynard, J. B. Cazier, F. Buffa, P. J. McHugh, I. Tomlinson, M. R. Middleton, R. A. Sharma
Publikováno v:
Scientific Reports, Vol 8, Iss 1, Pp 1-9 (2018)
Abstract Oxaliplatin-based chemotherapy is used to treat patients with esophageal adenocarcinoma (EAC), but no biomarkers are currently available for patient selection. We performed a prospective, clinical trial to identify potential biomarkers assoc
Externí odkaz:
https://doaj.org/article/4d0870d7f2504c6cb7bd6fa3f5792e59