Výsledky vyhledávání - "M. Filip Sluzewski"

Integrated intracellular organization and its variations in human iPS cells

Autor: Matheus P. Viana, Jianxu Chen, Theo A. Knijnenburg, Ritvik Vasan, Calysta Yan, Joy E. Arakaki, Matte Bailey, Ben Berry, Antoine Borensztejn, Eva M. Brown, Sara Carlson, Julie A. Cass, Basudev Chaudhuri, Kimberly R. Cordes Metzler, Mackenzie E. Coston, Zach J. Crabtree, Steve Davidson, Colette M. DeLizo, Shailja Dhaka, Stephanie Q. Dinh, Thao P. Do, Justin Domingus, Rory M. Donovan-Maiye, Alexandra J. Ferrante, Tyler J. Foster, Christopher L. Frick, Griffin Fujioka, Margaret A. Fuqua, Jamie L. Gehring, Kaytlyn A. Gerbin, Tanya Grancharova, Benjamin W. Gregor, Lisa J. Harrylock, Amanda Haupt, Melissa C. Hendershott, Caroline Hookway, Alan R. Horwitz, H. Christopher Hughes, Eric J. Isaac, Gregory R. Johnson, Brian Kim, Andrew N. Leonard, Winnie W. Leung, Jordan J. Lucas, Susan A. Ludmann, Blair M. Lyons, Haseeb Malik, Ryan McGregor, Gabe E. Medrash, Sean L. Meharry, Kevin Mitcham, Irina A. Mueller, Timothy L. Murphy-Stevens, Aditya Nath, Angelique M. Nelson, Sandra A. Oluoch, Luana Paleologu, T. Alexander Popiel, Megan M. Riel-Mehan, Brock Roberts, Lisa M. Schaefbauer, Magdalena Schwarzl, Jamie Sherman, Sylvain Slaton, M. Filip Sluzewski, Jacqueline E. Smith, Youngmee Sul, Madison J. Swain-Bowden, W. Joyce Tang, Derek J. Thirstrup, Daniel M. Toloudis, Andrew P. Tucker, Veronica Valencia, Winfried Wiegraebe, Thushara Wijeratna, Ruian Yang, Rebecca J. Zaunbrecher, Ramon Lorenzo D. Labitigan, Adrian L. Sanborn, Graham T. Johnson, Ruwanthi N. Gunawardane, Nathalie Gaudreault, Julie A. Theriot, Susanne M. Rafelski

Publikováno v: Nature. 613:345-354

Understanding how a subset of expressed genes dictates cellular phenotype is a considerable challenge owing to the large numbers of molecules involved, their combinatorics and the plethora of cellular behaviours that they determine1,2. Here we reduce

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a684c7c821c5ce222400005b63258558
https://doi.org/10.1038/s41586-022-05563-7

Zobrazit plný text záznamu

Microglial Calcium Waves During the Hyperacute Phase of Ischemic Stroke

Autor: M. Yashar S. Kalani, Elizabeth W.J. Carlson, Petr Tvrdik, M. Filip Sluzewski, Scott T. Acton, Min S. Park, Sauson Soldozy, Khadijeh A Sharifi, Ilyas M. Eli, Kenneth A. Stauderman, Kathryn N. Kearns, Lei Liu, Kyle W. Scott

Publikováno v: Stroke

Background and Purpose: Ischemic injury triggers multiple pathological responses in the brain tissue, including spreading depolarizations across the cerebral cortex (cortical spreading depolarizations [CSD]). Microglia have been recently shown to pla

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::659ef48984026f1b37423ad2770ef4e6
https://pubmed.ncbi.nlm.nih.gov/33268849

Zobrazit plný text záznamu

Cell states beyond transcriptomics: integrating structural organization and gene expression in hiPSC-derived cardiomyocytes

SummaryWe present a quantitative co-analysis of RNA abundance and sarcomere organization in single cells and an integrated framework to predict subcellular organization states from gene expression. We used human induced pluripotent stem cell (hiPSC)-

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::0e326e27fbf7fc65e085222dc6bf70aa
https://doi.org/10.1101/2020.05.26.081083

Zobrazit plný text záznamu

Cell states beyond transcriptomics: Integrating structural organization and gene expression in hiPSC-derived cardiomyocytes

Publikováno v: Cell systems. 12(6)

Although some cell types may be defined anatomically or by physiological function, a rigorous definition of cell state remains elusive. Here, we develop a quantitative, imaging-based platform for the systematic and automated classification of subcell

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::38acfcd6fa500b96ee66a4ee9154b335
https://pubmed.ncbi.nlm.nih.gov/34043964

Zobrazit plný text záznamu

Segmentation of Cortical Spreading Depression Wavefronts Through Local Similarity Metric

Autor: Petr Tvrdik, Scott T. Acton, M. Filip Sluzewski

Publikováno v: ICIP

In this paper, we present a novel region-based segmentation method for cortical spreading depressions in 2-photon microscopy images. Fluorescent microscopy has become an important tool in neuroscience, but segmentation approaches are challenged by th

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::747533f84237ccb4bf9f101b1ba56ecf
https://doi.org/10.1109/icip.2019.8803099

Zobrazit plný text záznamu

Calcium Imaging of Microglial Network Activity in Stroke

Autor: Petr, Tvrdik, Kathryn N, Kearns, Khadijeh A, Sharifi, M Filip, Sluzewski, Scott T, Acton, M Yashar S, Kalani

Publikováno v: Methods in molecular biology (Clifton, N.J.). 2034

Calcium signaling plays a significant role in microglial activation. Genetically encoded calcium indicators (GECI) have been widely used for calcium imaging studies in many brain cell types, including neurons, astrocytes, and oligodendrocytes. Howeve

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::16aee2417be4a3bb03a8309a13a0c603
https://pubmed.ncbi.nlm.nih.gov/31392691

Zobrazit plný text záznamu

Calcium Imaging of Microglial Network Activity in Stroke

Autor: Kathryn N. Kearns, M. Yashar S. Kalani, M. Filip Sluzewski, Scott T. Acton, Khadijeh A Sharifi, Petr Tvrdik

Publikováno v: Microglia ISBN: 9781493996575

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::b8ad21ecf583ff1fd4664ad173e3d41a
https://doi.org/10.1007/978-1-4939-9658-2_19

Zobrazit plný text záznamu

Vyhledávací nástroje:

Upřesnit hledání