Zobrazeno 1 - 10
of 10
pro vyhledávání: '"M. Fethullah Simsek"'
Publikováno v:
Open Biology, Vol 12, Iss 10 (2022)
Metazoan embryos develop from a single cell into three-dimensional structured organisms while groups of genetically identical cells attain specialized identities. Cells of the developing embryo both create and accurately interpret morphogen gradients
Externí odkaz:
https://doaj.org/article/82baf4797f7448b7ab81862929e9374b
Autor:
Sevdenur Keskin, M. Fethullah Simsek, Ha T. Vu, Carlton Yang, Stephen H. Devoto, Ahmet Ay, Ertuğrul M. Özbudak
Publikováno v:
iScience, Vol 12, Iss , Pp 247-259 (2019)
Summary: Gene regulatory networks govern pattern formation and differentiation during embryonic development. Segmentation of somites, precursors of the vertebral column among other tissues, is jointly controlled by temporal signals from the segmentat
Externí odkaz:
https://doaj.org/article/5c0e98c1f81740fab8ec45c0e02aa896
Publikováno v:
Cell Reports, Vol 24, Iss 1, Pp 66-78.e8 (2018)
Summary: Signal gradients encode instructive information for numerous decision-making processes during embryonic development. A striking example of precise, scalable tissue-level patterning is the segmentation of somites—the precursors of the verte
Externí odkaz:
https://doaj.org/article/1c85c0f8e77c4519aa6dfe545dd363ba
Autor:
M. Fethullah Simsek, Angad Singh Chandel, Didar Saparov, Oriana Q. H. Zinani, Nicholas Clason, Ertuğrul M. Özbudak
Publikováno v:
Nature
Sequential segmentation creates modular body plans of diverse metazoan embryos(1-4). Somitogenesis establishes segmental pattern of vertebrate body axis. A molecular segmentation clock in the presomitic mesoderm (PSM) sets the pace of somite formatio
Publikováno v:
Cell Stem Cell. 30:246-247
Publikováno v:
PLoS ONE, Vol 10, Iss 3, p e0121777 (2015)
Membrane bound cell signaling is modulated by the membrane ultra-structure, which itself may be affected by signaling. However, measuring the interaction of membrane proteins with membrane structures in intact cells in real-time poses considerable ch
Externí odkaz:
https://doaj.org/article/76bd72ff27f944fdad77475fce6e399a
Publikováno v:
J Vis Exp
Vertebrate embryos pattern their major body axis as repetitive somites, the precursors of vertebrae, muscle, and skin. Somites progressively segment from the presomitic mesoderm (PSM) as the tail end of the embryo elongates posteriorly. Somites form
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3867c732f4a3be677a17f408567d8a90
https://europepmc.org/articles/PMC8420939/
https://europepmc.org/articles/PMC8420939/
Publikováno v:
Cell Reports, Vol 24, Iss 1, Pp 66-78.e8 (2018)
Cell reports
Cell reports
SUMMARY Signal gradients encode instructive information for numerous decision-making processes during embryonic development. A striking example of precise, scalable tissue-level patterning is the segmentation of somites—the precursors of the verteb
Autor:
Ahmet Ay, M. Fethullah Simsek, Ha T. Vu, Stephen H. Devoto, Sevdenur Keskin, Carlton Yang, Ertuğrul M. Özbudak
Publikováno v:
iScience
iScience, Vol 12, Iss, Pp 247-259 (2019)
iScience, Vol 12, Iss, Pp 247-259 (2019)
Summary Gene regulatory networks govern pattern formation and differentiation during embryonic development. Segmentation of somites, precursors of the vertebral column among other tissues, is jointly controlled by temporal signals from the segmentati
Publikováno v:
Methods (San Diego, Calif.).
It has been long recognized that the cell membrane is heterogeneous on scales ranging from a couple of molecules to micrometers in size and hence diffusion of receptors is length scale dependent. This heterogeneity modulates many cell-membrane-associ