Zobrazeno 1 - 10
of 17
pro vyhledávání: '"M. Felicia Davatolhagh"'
Publikováno v:
Cell Reports, Vol 34, Iss 8, Pp 108773- (2021)
Summary: Mutations in genes essential for synaptic function, such as the presynaptic adhesion molecule Neurexin1α (Nrxn1α), are strongly implicated in neuropsychiatric pathophysiology. As the input nucleus of the basal ganglia, the striatum integra
Externí odkaz:
https://doaj.org/article/baaa4cdda6734ba8bd58840cec95396d
Autor:
André O. White, Enikö A. Kramár, Alberto J. López, Janine L. Kwapis, John Doan, David Saldana, M. Felicia Davatolhagh, Yasaman Alaghband, Mathew Blurton-Jones, Dina P. Matheos, Marcelo A. Wood
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-12 (2016)
Epigenetic mechanisms play a key role in drug-associated memories and behaviors. Here authors show that mice deficient of BAF53b, a nucleosome remodeling complex subunit, display deficits in synaptic plasticity and cocaine-associated memory, both of
Externí odkaz:
https://doaj.org/article/37dbd22580704fe786b26acb2218046b
Autor:
Opeyemi O Alabi, M Felicia Davatolhagh, Mara Robinson, Michael P Fortunato, Luigim Vargas Cifuentes, Joseph W Kable, Marc Vincent Fuccillo
Publikováno v:
eLife, Vol 9 (2020)
Goal-directed behaviors are essential for normal function and significantly impaired in neuropsychiatric disorders. Despite extensive associations between genetic mutations and these disorders, the molecular contributions to goal-directed dysfunction
Externí odkaz:
https://doaj.org/article/d362ce23741446668eea15b10e8024b7
Autor:
Michael P Fortunato, Joseph W. Kable, M. Felicia Davatolhagh, Opeyemi O. Alabi, Marc V. Fuccillo, Mara Robinson, Luigim Vargas Cifuentes
Publikováno v:
eLife, Vol 9 (2020)
eLife
eLife
Goal-directed behaviors are essential for normal function and significantly impaired in neuropsychiatric disorders. Despite extensive associations between genetic mutations and these disorders, the molecular contributions to goal-directed dysfunction
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fe631a86c9cf9fd6c9b40ec2e6b75158
https://elifesciences.org/articles/54838
https://elifesciences.org/articles/54838
Autor:
M. Felicia Davatolhagh, Marc V. Fuccillo, Zijie Xia, Sheng Tang, Barbara Terzic, Zhaolan Zhou, Yue Cui, Yugong Ho, Yu-Ting Liu
Publikováno v:
J Clin Invest
CDKL5 deficiency disorder (CDD) is an early onset, neurodevelopmental syndrome associated with pathogenic variants in the X-linked gene encoding cyclin-dependent kinase-like 5 (CDKL5). CDKL5 has been implicated in neuronal synapse maturation, yet its
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a9439770cb824c3c3626bd3ea1edc3c8
https://pubmed.ncbi.nlm.nih.gov/34720088
https://pubmed.ncbi.nlm.nih.gov/34720088
Low-threshold spiking interneurons (LTSIs) in the dorsomedial striatum are potent modulators of goal-directed learning. Here, we uncover a novel function for LTSIs in locally and directly gating striatal dopamine, using in vitro fast scan cyclic volt
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::07529e80a818ab642b279e0e54ee780d
https://doi.org/10.1101/2020.08.03.235044
https://doi.org/10.1101/2020.08.03.235044
Autor:
Mara Robinson, Luigim Vargas Cifuentes, Marc V. Fuccillo, M. Felicia Davatolhagh, Opeyemi O. Alabi, Joseph W. Kable, Michael P Fortunato
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::74d1e81dfdcb30c3b6edace4036b570a
https://doi.org/10.7554/elife.54838.sa2
https://doi.org/10.7554/elife.54838.sa2
SummaryMutations in genes essential for shared aspects of synaptic function throughout the CNS, such as the presynaptic adhesion molecule Neurexin1α (Nrxn1α), are strongly implicated in neuropsychiatric pathophysiology. As the input nucleus of the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5e9dff4b618ecb35293b4b23da2127c5
https://doi.org/10.1101/2020.05.31.125575
https://doi.org/10.1101/2020.05.31.125575
Autor:
Ludivine Therreau, Katie N Clements, Vincent Robert, F. Javier Bernardo-Garcia, M. Felicia Davatolhagh, Rebecca A. Piskorowski, Vivien Chevaleyre
Publikováno v:
Journal of General Physiology
Journal of General Physiology, Rockefeller University Press, 2020, 152 (4), pp.e201912462. ⟨10.1085/jgp.201912462⟩
The Journal of General Physiology
Journal of General Physiology, 2020, 152 (4), pp.e201912462. ⟨10.1085/jgp.201912462⟩
Journal of General Physiology, Rockefeller University Press, 2020, 152 (4), pp.e201912462. ⟨10.1085/jgp.201912462⟩
The Journal of General Physiology
Journal of General Physiology, 2020, 152 (4), pp.e201912462. ⟨10.1085/jgp.201912462⟩
Robert et al. reveal that muscarinic receptor activation causes hippocampal CA2 pyramidal neurons to depolarize and fire bursts of action potentials. The properties of these bursts are regulated by synaptic inputs, as well as T-type calcium channels,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8a811c3893538eacc90d134b4e8af484
https://www.hal.inserm.fr/inserm-02771945/file/jgp_201912462.pdf
https://www.hal.inserm.fr/inserm-02771945/file/jgp_201912462.pdf
Publikováno v:
European Journal of Neuroscience. 49:623-636
The dorsomedial striatum, a key site of reward-sensitive motor output, receives extensive afferent input from cortex, thalamus and midbrain. These projections are integrated by striatal microcircuits containing both spiny projection neurons and local
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9c0a47e320e4752b9a8afc61a2e713ff
https://doi.org/10.1111/ejn.13829
https://doi.org/10.1111/ejn.13829