Zobrazeno 1 - 10
of 195
pro vyhledávání: '"M. Fatome"'
Autor:
Ghassoub Rima, Jacques Satge, Claude Lion, M. Fatome, Rodolphe Dagiral, J. D. Laval, V. Roman
Publikováno v:
Applied Organometallic Chemistry. 13:583-594
Several organosilicon and organogermanium compounds possessing radioprotective activity have been synthesized. In this paper, we describe the preparation and study of the pharmacological properties of new organometallic compounds such as metallathiaz
Autor:
S. Martin, J. Y. Delattre, M. Fatome, N. Colas-Linhart, I. Lamproglou, Hatem Fessi, C. Martin, Francis Puisieux
Publikováno v:
Journal de Chimie Physique et de Physico-Chimie Biologique. 95:804-807
Afin de definir l'action de la superoxyde dismutase Cu/Zn liposomale (LIPSOD) sur le dysfonctionnement d'apprentissage induit chez le rat Sprague-Dawley apres irradiation corporelle totale a preponderance neutronique, une etude comportementale (evite
Autor:
J. D. Laval, Ghassoub Rima, Christian Thiriot, Christine Martin, Henri Sentenac-Roumanou, M. Fatome, Claude Lion, Rodolphe Dagiral, Jacques Satge
Publikováno v:
Main Group Metal Chemistry, Vol 20, Iss 4, Pp 255-268 (1997)
Publikováno v:
Radiation Protection Dosimetry. 70:455-459
In the case of a criticality accident, there are two radiation components, i.e. neutron and gamma, and the exposure is heterogeneous. The available techniques are biophysical techniques, which can give data about the dose distribution and the neutron
Autor:
J. D. Laval, Ghassoub Rima, H. Sentenac-Roumanou, Jacques Satge, M. Fatome, Claude Lion, Rodolphe Dagiral
Publikováno v:
Applied Organometallic Chemistry. 10:113-123
Further to our work concerning organometallic compounds active in chemical radioprotection, we report the synthesis and pharmacological study (radioprotective activity, toxicity) of new germathiazolidines and germadithioacetals derived from cysteamin
Autor:
Gérard Leclerc, M Taroua, P. Demenge, M. H. Pera, M Fatome, G Taillandier, JD Laval, C. Ribuot
Publikováno v:
European Journal of Medicinal Chemistry. 31:589-595
Summary Ten semicarbazone and nine thiosemicarbazone 1,3-dithiolanes (α, β and γ) were prepared and tested as radioprotector agents. Dithiolane is well known for its radioprotective properties; this compound protects 78% of mice if 500 mg/kg is ad
Publikováno v:
Journal de Chimie Physique. 93:169-173
Cette etude vise a mieux comprendre le mecanisme d'action des rayonnements gamma et neutron sur le systeme nerveux central, et particulierement sur la transmission dopaminergique. L'influence de ces deux modalites d'irradiation sur la capture de 3 H-
Publikováno v:
Analytical Biochemistry. 227:101-111
The in vivo measurement of highly reactive free radicals, such as hydroxyl radical ( . OH), in humans is very difficult if not impossible. Specific markers are currently under investigation (amino acid hydroxylatin, protein, DNA adducts, and aromatic
Publikováno v:
European Journal of Medicinal Chemistry. 30:47-52
Summary N -(2-Acetylthioethyl)-1,3-propanediamine ( 13a , as its 2HBr salt, or 13b , as its 2CF 3 CO 2 H salt) and N,N′ -bis(2-acetylthioethyl)-1,3-propanediamine ( 16 , as its 2CF 3 CO 3 H salt) have been prepared and evaluated as potential radiop
Autor:
Ghassoub Rima, Claude Lion, H. Sentenac-Roumanou, Jacques Satge, P. Chabertier, O. Alazard, M. Fatome, J. D. Laval
Publikováno v:
Applied Organometallic Chemistry. 8:481-490
New germa- and silathiazolidines or germa- and siladithioacetals with N-allyl-substituted cysteamine and methylcysteamine ligands have been synthesized and their pharmacological properties (toxicity, radioprotective activity) have been studied. A not