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pro vyhledávání: '"M. Fatih Polat"'
Autor:
M. Fatih Polat
Publikováno v:
Molecules, Vol 27, Iss 11, p 3523 (2022)
One of the main areas of interest of synthetic organic chemistry is the rapid construction of small molecules with proven diverse biological activities for the development of new strategies to cure human health. In particular, the development of nove
Externí odkaz:
https://doaj.org/article/b38433abb26c4620ad5f6d14f0484e7d
Akademický článek
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Autor:
M. Fatih Polat, Derya Aktas Anil
Publikováno v:
Organic Communications, Vol 13, Iss 1, Pp 19-27 (2020)
In this study, 2′,4′,6′-Trimethoxyacetophenone was reacted with various fluorine-substituted benzaldehydes in the presence of an aqueous solution of 50%-potassium hydroxide, and new chalcone derivatives in the structure of 1,3-diaryl-2-propenon
Autor:
Derya Aktas Anil, M. Fatih Polat, Ruya Saglamtas, Ayse H. Tarikogullari, M. Abdullah Alagoz, Ilhami Gulcin, Oztekin Algul, Serdar Burmaoglu
Enzyme inhibition is a very active area of research in drug design and development. Chalcone derivatives have a broad enzyme inhibitory activity and function as potential molecules in the development of new drugs. In this study, the synthesized novel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::36c5aba484208c0a9195d9e91e6614ab
https://hdl.handle.net/11454/76484
https://hdl.handle.net/11454/76484
Autor:
Erhan Tek, M. Abdullah Alagoz, Funda Cimen, Baris Anil, Derya Aktaş, Oztekin Algul, Serdar Burmaoglu, Emrah Ay, M. Fatih Polat, Nizami Duran
Publikováno v:
International Journal of Clinical Practice
Aims Flavonoids and related compounds, such as quercetin‐based antiviral drug Gene‐Eden‐VIR/Novirin, inhibit the protease of severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2). The alkylated chalcones isolated from Angelica keiske
Autor:
Nizami Duran, M. Fatih Polat, Derya Anil Aktas, M. Abdullah Alagoz, Emrah Ay, Funda Cimen, Erhan Tek, Baris Anil, Serdar Burmaoglu, Oztekin Algul
Flavonoids and related compounds, such as quercetin-based antiviral drug Gene-Eden-VIR/Novirin, inhibit the protease of severe acute respiratory syndrome coronavirus (SARS-CoV-2). The alkylated chalcones isolated from Angelica keiskei inhibit SARS-Co
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::354e88ea4974e96daf8a7b670c21af2c
https://doi.org/10.21203/rs.3.rs-515050/v1
https://doi.org/10.21203/rs.3.rs-515050/v1
Publikováno v:
Archives of Physiology and Biochemistry. 127:153-161
In this study, we report the synthesis of novel tris-chalcones and testing of human carbonic anhydrase I, and II isoenzymes (hCA I, and hCA II), acetylcholinesterase (AChE), butyrylcholinesterase (BChE), and alpha-glycosidase (alpha-Gly) inhibitors f
Autor:
Meral Tuncbilek, M. Fatih Polat
Publikováno v:
Nucleosides, nucleotidesnucleic acids. 40(3)
Antimetabolites, which are metabolic antagonists used in the treatment of cancer and viral diseases by replacing metabolites, inhibit the action of metabolic enzymes and disrupt the pathways of synthesis of structural units necessary for the formatio
Publikováno v:
Bioorganic chemistry. 85
A novel class of fluoro-substituted tris-chalcones derivatives (5a-5i) was synthesized from phloroglucinol and corresponding benzaldehydes. A three step synthesis method was followed for the production of these trischalcone compounds. The structures
Akademický článek
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