Zobrazeno 1 - 10
of 89
pro vyhledávání: '"M. Farfel"'
Autor:
Megan T. Lynch, Margaret A. Taub, Jose M. Farfel, Jingyun Yang, Peter Abadir, Philip L. De Jager, Francine Grodstein, David A. Bennett, Rasika A. Mathias
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-11 (2023)
Abstract Telomere length (TL) attrition, epigenetic age acceleration, and mitochondrial DNA copy number (mtDNAcn) decline are established hallmarks of aging. Each has been individually associated with Alzheimer’s dementia, cognitive function, and p
Externí odkaz:
https://doaj.org/article/6ff218eea22048358a72390dd75c2eed
Autor:
Sonal Agrawal, Jose M. Farfel, Konstantinos Arfanakis, Lena Al-Harthi, Tanner Shull, Tara L. Teppen, Arnold M. Evia, Mayur B. Patel, E. Wesley Ely, Sue. E. Leurgans, David A. Bennett, Rupal Mehta, Julie A. Schneider
Publikováno v:
Acta Neuropathologica Communications, Vol 10, Iss 1, Pp 1-16 (2022)
Abstract Background This study examined neuropathological findings of patients who died following hospitalization in an intensive care unit with SARS-CoV-2. Methods Data originate from 20 decedents who underwent brain autopsy followed by ex-vivo imag
Externí odkaz:
https://doaj.org/article/8ca981d6caa448c7bc691ebccb3bcd45
Autor:
Yuriko Katsumata, Lincoln M. Shade, Timothy J. Hohman, Julie A. Schneider, David A. Bennett, Jose M. Farfel, Walter A. Kukull, David W. Fardo, Peter T. Nelson
Publikováno v:
Neurobiology of Disease, Vol 174, Iss , Pp 105880- (2022)
The classic pathologic hallmarks of Alzheimer's disease (AD) are amyloid plaques and neurofibrillary tangles (AD neuropathologic changes, or ADNC). However, brains from individuals clinically diagnosed with “AD-type” (amnestic) dementia usually h
Externí odkaz:
https://doaj.org/article/51c903a874c840ef85fca47a6a221f58
Autor:
Jose M. Farfel, Lei Yu, Patricia A. Boyle, Sue Leurgans, Raj C. Shah, Julie A. Schneider, David A. Bennett
Publikováno v:
Acta Neuropathologica Communications, Vol 7, Iss 1, Pp 1-9 (2019)
Abstract Age is the most robust risk factor for Alzheimer’s dementia, however there is little data on the relation of age to Alzheimer’s disease (AD) and other common neuropathologies that contribute to Alzheimer’s dementia. We use data from tw
Externí odkaz:
https://doaj.org/article/ead40087ad6f4173b9589ad6e6656bdc
Autor:
Jose M Farfel, Sue E Leurgans, Ana W Capuano, Maria Carolina de Moraes Sampaio, Robert S Wilson, Julie A Schneider, David A Bennett
Publikováno v:
PLoS ONE, Vol 16, Iss 12, p e0261036 (2021)
BackgroundWhile dementia has been associated with specific causes of death, previous studies were relatively small autopsy series or population-based studies lacking autopsy confirmation and were restricted to Non-Latinx Whites. Here, we examine the
Externí odkaz:
https://doaj.org/article/2c6491933f924f1ab843ff2d722cacf7
Autor:
Robert S. Wilson, Ana W Capuano, Carolina Sampaio, Sue E. Leurgans, Lisa L. Barnes, Jose M. Farfel, David A. Bennett
Publikováno v:
Alzheimer’s & Dementia: Diagnosis, Assessment & Disease Monitoring, Vol 13, Iss 1, Pp n/a-n/a (2021)
Abstract Introduction Knowledge is limited about behavioral and psychological symptoms of mild cognitive impairment (MCI) and dementia in racial and ethnic minorities. Methods As part of the Pathology, Alzheimer's and Related Dementias Study (PARDoS)
Externí odkaz:
https://doaj.org/article/6998d16d41764b9f85c244e1bfdea42a
Autor:
Joseph Pauza, Y. J. Zhang, A. Deal, M. Farfel, B. Griffith, A. Choi, Anthony D. Rollett, M. Bennett, R. Deering, K. Johnson, Jerard V. Gordon
Publikováno v:
Journal of Materials Engineering and Performance. 30:8735-8745
The simulation and modeling of part-level distortion and residual stress in diverse metal additive manufacturing (AM) geometries has great potential to enable the rapid adoption of this technology in engineering design. Moreover, the use of additive
Autor:
Claudia K Suemoto, Renata E L Ferretti-Rebustini, Roberta D Rodriguez, Renata E P Leite, Luciana Soterio, Sonia M D Brucki, Raphael R Spera, Tarcila M Cippiciani, Jose M Farfel, Alexandre Chiavegatto Filho, Michel Satya Naslavsky, Mayana Zatz, Carlos A Pasqualucci, Wilson Jacob-Filho, Ricardo Nitrini, Lea T Grinberg
Publikováno v:
PLoS Medicine, Vol 14, Iss 3, p e1002267 (2017)
BACKGROUND:Clinicopathological studies are important in determining the brain lesions underlying dementia. Although almost 60% of individuals with dementia live in developing countries, few clinicopathological studies focus on these individuals. We i
Externí odkaz:
https://doaj.org/article/b96735f0fc084b65a9266e154e837810
Autor:
Aline Nishizawa, Claudia K Suemoto, Daniela S Farias-Itao, Fernanda M Campos, Karen C S Silva, Marcio S Bittencourt, Lea T Grinberg, Renata E P Leite, Renata E L Ferretti-Rebustini, Jose M Farfel, Wilson Jacob-Filho, Carlos A Pasqualucci
Publikováno v:
PLoS ONE, Vol 12, Iss 10, p e0186630 (2017)
BACKGROUND:Morphometric measurements of systemic atherosclerosis and direct quantification of visceral fat are only possible using materials from autopsy studies. However, the few autopsy studies that have investigated the association of visceral fat
Externí odkaz:
https://doaj.org/article/70c8eecd75144dc5b850c12d8393a049
Autor:
Kelly G. Knupp, Ingrid E. Scheffer, Berten Ceulemans, Joseph E. Sullivan, Katherine C. Nickels, Lieven Lagae, Renzo Guerrini, Sameer M. Zuberi, Rima Nabbout, Kate Riney, Svetlana Shore, Anupam Agarwal, Michael Lock, Gail M. Farfel, Bradley S. Galer, Arnold R. Gammaitoni, Ronald Davis, Antonio Gil-Nagel
Publikováno v:
JAMA neurology
IMPORTANCE: New treatment options are needed for patients with Lennox-Gastaut syndrome (LGS), a profoundly impairing, treatment-resistant, developmental and epileptic encephalopathy. OBJECTIVE: To evaluate the efficacy and safety of fenfluramine in p