Zobrazeno 1 - 10
of 129
pro vyhledávání: '"M. Faß"'
Autor:
Chialin Cheng, Surya A. Reis, Emily T. Adams, Daniel M. Fass, Steven P. Angus, Timothy J. Stuhlmiller, Jared Richardson, Hailey Olafson, Eric T. Wang, Debasis Patnaik, Roberta L. Beauchamp, Danielle A. Feldman, M. Catarina Silva, Mriganka Sur, Gary L. Johnson, Vijaya Ramesh, Bruce L. Miller, Sally Temple, Kenneth S. Kosik, Bradford C. Dickerson, Stephen J. Haggarty
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-21 (2021)
Abstract Mutations in MAPT (microtubule-associated protein tau) cause frontotemporal dementia (FTD). MAPT mutations are associated with abnormal tau phosphorylation levels and accumulation of misfolded tau protein that can propagate between neurons u
Externí odkaz:
https://doaj.org/article/dbd7b9c359124c2ab41cec4cd38e2e30
Autor:
Marina Kovalenko, Serkan Erdin, Marissa A Andrew, Jason St Claire, Melissa Shaughnessey, Leroy Hubert, João Luís Neto, Alexei Stortchevoi, Daniel M Fass, Ricardo Mouro Pinto, Stephen J Haggarty, John H Wilson, Michael E Talkowski, Vanessa C Wheeler
Publikováno v:
eLife, Vol 9 (2020)
Somatic expansion of the Huntington’s disease (HD) CAG repeat drives the rate of a pathogenic process ultimately resulting in neuronal cell death. Although mechanisms of toxicity are poorly delineated, transcriptional dysregulation is a likely cont
Externí odkaz:
https://doaj.org/article/7ec6f42abf9f427c8434769cf8737ee8
Akademický článek
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Laser welding of 16MnCr5 butt welds with gap: resulting weld quality and fatigue strength assessment
For laser welding, gaps should normally be avoided to ensure stable weld processes and high weld quality. Nonetheless, sometimes, gaps are resulting from non-optimal weld preparation in industrial applications. Within this investigation, the effects
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7a97b08cafcd487235814f1dec2c121d
https://publica.fraunhofer.de/handle/publica/419256
https://publica.fraunhofer.de/handle/publica/419256
Autor:
Daniel M. Fass, Roberta L. Beauchamp, Steven P. Angus, Chialin Cheng, Kenneth S. Kosik, Timothy J. Stuhlmiller, Bradford C. Dickerson, Bruce L. Miller, Debasis Patnaik, Danielle A. Feldman, Jared I Richardson, Stephen J. Haggarty, Hailey Olafson, Surya A. Reis, Mriganka Sur, Gary L. Johnson, Vijaya Ramesh, Eric T. Wang, Sally Temple, Emily T Adams, M. Catarina Silva
Publikováno v:
Scientific Reports
Scientific reports, vol 11, iss 1
Scientific Reports, Vol 11, Iss 1, Pp 1-21 (2021)
Scientific reports, vol 11, iss 1
Scientific Reports, Vol 11, Iss 1, Pp 1-21 (2021)
Mutations in MAPT (microtubule-associated protein tau) cause frontotemporal dementia (FTD). MAPT mutations are associated with abnormal tau phosphorylation levels and accumulation of misfolded tau protein that can propagate between neurons ultimately
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::648e69bd4afba94c17b3f3502a46e0b7
http://europepmc.org/articles/PMC8382845
http://europepmc.org/articles/PMC8382845
Autor:
Carlos Moreno-Yruela, Chialin Cheng, Christian A. Olsen, Daniel M. Fass, Joachim Herz, Stephen J. Haggarty
Publikováno v:
Moreno-Yruela, C, Fass, D M, Cheng, C, Herz, J, Olsen, C A & Haggarty, S J 2019, ' Kinetic Tuning of HDAC Inhibitors Affords Potent Inducers of Progranulin Expression ', A C S Chemical Neuroscience, vol. 10, no. 8, pp. 3769-3777 . https://doi.org/10.1021/acschemneuro.9b00281
ACS Chem Neurosci
ACS Chem Neurosci
Histone deacetylases (HDACs) are enzymes involved in the epigenetic control of gene expression. A handful of HDAC inhibitors have been approved for the treatment of cancer, and HDAC inhibition has also been proposed as a novel therapeutic strategy fo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e1955d103b83b2645def8b6fc79d7e25
https://doi.org/10.1021/acschemneuro.9b00281
https://doi.org/10.1021/acschemneuro.9b00281
Autor:
Frederick A Schroeder, Michael C Lewis, Daniel M Fass, Florence F Wagner, Yan-Ling Zhang, Krista M Hennig, Jennifer Gale, Wen-Ning Zhao, Surya Reis, Douglas D Barker, Erin Berry-Scott, Sung Won Kim, Elizabeth L Clore, Jacob M Hooker, Edward B Holson, Stephen J Haggarty, Tracey L Petryshen
Publikováno v:
PLoS ONE, Vol 8, Iss 8, p e71323 (2013)
Psychiatric diseases, including schizophrenia, bipolar disorder and major depression, are projected to lead global disease burden within the next decade. Pharmacotherapy, the primary--albeit often ineffective--treatment method, has remained largely u
Externí odkaz:
https://doaj.org/article/f98bfbbf4c0c4abda75478a1de4329d5
Autor:
Ricardo Mouro Pinto, Marissa A Andrew, Michael E. Talkowski, João Luís Neto, Daniel M. Fass, Jason St. Claire, Melissa Shaughnessey, Marina Kovalenko, John H. Wilson, Alexei Stortchevoi, Stephen J. Haggarty, Leroy Hubert, Vanessa C. Wheeler, Serkan Erdin
Publikováno v:
eLife, Vol 9 (2020)
eLife
eLife
Somatic expansion of the Huntington’s disease (HD) CAG repeat drives the rate of a pathogenic process ultimately resulting in neuronal cell death. Although mechanisms of toxicity are poorly delineated, transcriptional dysregulation is a likely cont
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d4bab383dbf15df6044f9404456e723d
https://elifesciences.org/articles/55911
https://elifesciences.org/articles/55911