Zobrazeno 1 - 10
of 13
pro vyhledávání: '"M. F. W. Festing"'
Publikováno v:
Laboratory Animals. 42:12-18
Summary In vivo models of hepatic ischaemia/reperfusion injury (IRI) are widely used to study both the mechanisms of hepatic ischaemic injury and to seek means of hepatic protection. Achieving high-quality reproducible data are essential if the resul
Publikováno v:
Parasite Immunology. 1:125-132
Summary The course of each of three successive infections with Eimeria nieschulzi in nude (athymic) rats was the same as the primary infection in nu/+ animals, with the production of more oocysts. This indicates that resistance to reinfection with th
Autor:
M. F. W. Festing
Publikováno v:
Aging Clinical and Experimental Research. 5:309-315
Laboratory rodents are widely used in gerontological research. Many different strains are available, and superficially there is little to distinguish them (many are albino), although they may differ markedly in life span and pattern of spontaneous di
Autor:
M. F. W. Festing
Publikováno v:
Experientia. 47:990-998
Animals have evolved a detoxication system to enable them to survive in a hostile chemical environment in which foods contain many non-nutrient chemicals. Detoxication depends on enzymes which are often genetically polymorphic. As a result, inter-ind
Publikováno v:
Genetical Research. 49:235-238
SummaryAnimal models which emulate defects similar to those in man are required for medical research. Many investigations on the cellular, developmental and molecular aspects of cataractogenesis use the cataract Fraser (CatFr) mouse. This report show
Autor:
J. C. Whitney, P. J. Crossman, T. Graham-Marr, M. E. Hugh-Jones, D. K. Blackmore, D. Krzysiak, G. H. Townsend, A. C. Rowland, R. J. Parkin, M. F. W. Festing
Publikováno v:
Laboratory Animals. 10:203-207
In a survey of mortality in 2224 rabbits of up to 12 weeks of age, drawn from 10 production units, neonatal mortality was important with 111 still-births and 175 deaths in the 1st week of life out of a total of 457 deaths in the whole survey. There w
Autor:
M. F. W. Festing
Publikováno v:
Immunodeficient Animals for Cancer Research ISBN: 9781349050161
The immune system of mammals has evolved as one of the most important protective mechanisms against infection by parasites, bacteria and viruses, and possibly also as a protection against malignant clones arising as a result of somatic mutation, that
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f3083be80139c8192adc558199e5b4a0
https://doi.org/10.1007/978-1-349-05014-7_2
https://doi.org/10.1007/978-1-349-05014-7_2
Autor:
M. F. W. Festing
Publikováno v:
Animal Models in Parasitology ISBN: 9781349061389
A wide range of genetically defined laboratory animals are now being used by parasitologists as a means of investigating host-parasite relationships. These defined animals include inbred, congenic and recombinant inbred strains, F1 hybrids and a wide
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::99dd8386951d1e4fd683ac4ebc7001fd
https://doi.org/10.1007/978-1-349-06136-5_1
https://doi.org/10.1007/978-1-349-06136-5_1
Autor:
M. F. W. Festing
Publikováno v:
Animal Models of Obesity ISBN: 9781349042036
Obesity in laboratory animals may be inherited either as a single-gene Mendelian or as a polygenic character. A sharp distinction must be made between these two forms of inheritance. In the case of the Mendelian models, genetic theory suggests that t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e7c2592845bd70ca7bfad2c0488f9692
https://doi.org/10.1007/978-1-349-04201-2_2
https://doi.org/10.1007/978-1-349-04201-2_2
Autor:
M. F. W. Festing
Publikováno v:
Archives of Toxicology ISBN: 9783540165897
The fundamental principle of the controlled experiment is that treated and control goups should be identical, with minimal within-group variability. Toxicologists recognise this and control age, body weight, disease and the physical environment of th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1171c91871d3a9244acf8348f3b4320e
https://doi.org/10.1007/978-3-642-71248-7_15
https://doi.org/10.1007/978-3-642-71248-7_15