Zobrazeno 1 - 10
of 11
pro vyhledávání: '"M. F. Usiak"'
Publikováno v:
Neuron. 4:253-267
We have analyzed alternatively spliced beta amyloid protein precursor (beta APP) mRNAs by using the polymerase chain reaction to amplify beta APP cDNAs produced by reverse transcription. With this approach the three previously characterized beta APP
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b3fbabf1ca7a88f7f3ef94fa1a50586c
https://doi.org/10.1016/0896-6273(90)90100-t
https://doi.org/10.1016/0896-6273(90)90100-t
Autor:
M. F. Usiak, Lynn T. Landmesser
To understand better how spontaneous motoneuron activity and intramuscular nerve branching influence motoneuron survival, we chronically treated chicken embryos in ovo with either d-tubocurarine (dTC) or muscimol during the naturally occurring cell d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::08a1517970d51a3a08b411f9fc1f78ab
https://europepmc.org/articles/PMC6782443/
https://europepmc.org/articles/PMC6782443/
Publikováno v:
Anesthesiology. 85(2)
Background In previous studies, researchers demonstrated the ability of a variety of organisms and in vitro sites of anesthetic action to distinguish between stereoisomers of isoflurane or halothane. However, it was not shown whether organisms with d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::80d852ae829eccc03674f326d0d1b40d
https://pubmed.ncbi.nlm.nih.gov/8712455
https://pubmed.ncbi.nlm.nih.gov/8712455
Publikováno v:
Biochemical and biophysical research communications. 200(3)
The amyloid beta protein (A beta), a 4 kD fragment of the beta amyloid precursor protein, is deposited as insoluble amyloid in the brain of Alzheimer disease (AD) subjects. Soluble A beta is a normal metabolic product and is present in cerebrospinal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2e03bd5c3f32bfe565e179bfeb81da76
https://pubmed.ncbi.nlm.nih.gov/8185615
https://pubmed.ncbi.nlm.nih.gov/8185615
Autor:
Wang R, Palmert Mr, Gonzalez-De Whitt Pa, Pasternack Jm, M. B. Fairbanks, Robert L. Heinrikson, Blades D, Cheung T, M. F. Usiak, H. Zurcher-Neely
Publikováno v:
Biochemistry. 31(44)
The 39-43 amino acid beta amyloid protein (A beta) that deposits as amyloid in the brains of patients with Alzheimer's disease (AD) is encoded as an internal sequence within a larger membrane-associated protein known as the amyloid protein precursor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b51453f1abba1af319d140c67c050a70
https://pubmed.ncbi.nlm.nih.gov/1420205
https://pubmed.ncbi.nlm.nih.gov/1420205
Publikováno v:
Journal of Biological Chemistry. 261:1201-1207
A pulse-chase experiment was performed in embryonic rat myotube cultures to examine possible precursor-product relationships among the various molecular forms of acetylcholinesterase (AChE). AChE was labeled with paraoxon, a compound which diethylpho
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::944505c1dbb60ec9f2017e2d728ab8d3
https://doi.org/10.1016/s0021-9258(17)36076-3
https://doi.org/10.1016/s0021-9258(17)36076-3
Publikováno v:
Proceedings of the National Academy of Sciences. 85:1227-1231
To determine which cells within the brain produce beta-amyloid mRNA and to assess expression of the beta-amyloid gene in Alzheimer disease, we analyzed brain tissue from Alzheimer and control patients by in situ hybridization. Our results demonstrate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::310a7a33580f8898830e96a006983db5
https://doi.org/10.1073/pnas.85.4.1227
https://doi.org/10.1073/pnas.85.4.1227
Publikováno v:
The Journal of biological chemistry. 261(3)
A pulse-chase experiment was performed in embryonic rat myotube cultures to examine possible precursor-product relationships among the various molecular forms of acetylcholinesterase (AChE). AChE was labeled with paraoxon, a compound which diethylpho
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::d5102e447b7fd8662a018a5307f590a5
https://pubmed.ncbi.nlm.nih.gov/3944084
https://pubmed.ncbi.nlm.nih.gov/3944084
Autor:
Marcia B. Podlisny, Sandra L. Siedlak, Steven G. Younkin, Dennis J. Selkbe, Earl R. Shelton, Barry D. Greenberg, Hardy W. Chan, M. F. Usiak, Mark R. Palmert, George Perry
Publikováno v:
Biochemical and biophysical research communications. 165(1)
The amyloid deposited in Alzheimer's disease (AD) is composed primarily of a 39-42 residue polypeptide (beta AP) that is derived from a larger beta amyloid protein precursor (beta APP). In previous studies, we and others identified full-length, membr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8bc877ad285f994bbccdb44df36903aa
https://pubmed.ncbi.nlm.nih.gov/2480122
https://pubmed.ncbi.nlm.nih.gov/2480122
Publikováno v:
Federation proceedings. 45(13)
In this study, we examined 26 cases of Alzheimer's disease (AD) and 14 age-matched controls. In Brodmann area 21 cerebral cortex of the AD cases, there was no change in soluble G1 and G4 acetylcholinesterase (AChE) (EC 3.1.1.7), a significant 40% dec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::4cb7bd2bb1ed8ceeeee46156dab37d71
https://pubmed.ncbi.nlm.nih.gov/2430839
https://pubmed.ncbi.nlm.nih.gov/2430839