Zobrazeno 1 - 10
of 90
pro vyhledávání: '"M. F. Scully"'
Publikováno v:
Current Pharmaceutical Design. 14:2140-2158
Integrins have been reported to mediate cell survival, proliferation, differentiation, and migration programs. For this reason, the past few years have seen an increased interest in the implications of integrin receptors in atherosclerosis. This revi
Since its inception the research area of platelet pharmacology has always been a vigorous one and it is a characteristic that new approaches to the understanding of platelet function are rapidly and thoroughly investigated. The intensity of this acti
Publikováno v:
Current Medicinal Chemistry-Cardiovascular & Hematological Agents. 1:189-196
Integrins are a family of heterodimeric class I transmembrane receptors, many of which bind to the RGD sequence in adhesive proteins and mediate the adhesive interactions of a variety of cells. The RGD motif has also been found in snake venom protein
Autor:
Jianhong Wu, Paul Monagle, Patricia McCusker, K Ali, M.P. Massicotte, Margaret Adams, Sara J. Israels, M Mahoney, Dorothy R. Barnard, Jacqueline Halton, L Brisson, M. David, Michael Leaker, Maureen Andrew, Ross Anderson, M F Scully, Lawrence Jardine, Shalini Desai, M. Silva, M Bernstein
Publikováno v:
Pediatric Research. 47:763-766
The outcome for children with deep vein thrombosis (DVT) and pulmonary embolism (PE) is unknown. An understanding of morbidity and mortality of DVT/PE is crucial to the development of rational treatment protocols. The Canadian Childhood Thrombophilia
Publikováno v:
British Journal of Surgery. 82:1101-1104
The transmembrane cellular receptor tissue factor (TF) is the primary initiator of the coagulation cascade in man. Expression of TF was determined in 55 specimens of ductal adenocarcinoma of the pancreas and was found to correlate strongly with the d
Autor:
M F Scully, Cheng Hock Toh, Alan R. Giles, Reginald P. Manuel, Hugh Hoogendoorn, S Solymoss, Michael E. Nesheim
Publikováno v:
Thrombosis and Haemostasis. 69:448-453
Activation and inactivation of protein C during the clinical course of disseminated intravascular coagulation (DIC) was studied in three patients by qualitative (Western blotting) and quantitative (ELISA) analysis and the intensity of procoagulant ac
Autor:
M F Scully
Publikováno v:
Postgraduate Medical Journal. 67:848-855
Publikováno v:
Thrombosis and Haemostasis. 66:672-677
SummaryWhen the rate of lysis of artificial thrombi (prepared from plasma or whole blood) was expressed according to the concentration of tissue type plasminogen activator (t-PA) or single chain urokinase type plasminogen activator (sc-uPA) then bell
Publikováno v:
Thrombosis and Haemostasis. 64:550-555
SummaryA perfusion circuit was designed to investigate in vitro some of the factors which may influence the success of thrombolytic treatment in vivo. The rate of lysis of clotted plasma and different types of artificial thrombi (fibrin thrombi or wh
Publikováno v:
Haemophilia : the official journal of the World Federation of Hemophilia. 12
Men with haemophilia have not only the challenges of living with HIV and/or HCV infection and premature arthritis as complications of their disorder, but they also confront the other ails of ageing. These include genitourinary problems such as prosta