Zobrazeno 1 - 10 of 21 pro vyhledávání: '"M. F. Gordon"'
1
The effect of potent CYP2D6 inhibition on the pharmacokinetics and safety of deutetrabenazine in healthy volunteers
Autor: F. Schneider, P. S. Loupe, L. Rabinovich-Guilatt, M. F. Gordon, D. Stamler, M. J. Bradbury
Publikováno v: European Journal of Clinical Pharmacology
Purpose Deutetrabenazine is a deuterated form of tetrabenazine with a confirmed lower rate of CYP2D6 metabolism of the active metabolites, α- and β-HTBZ. In this study, we assessed the effect of paroxetine, a potent CYP2D6 inhibitor, on the pharmac
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cd84a87777c1f82f5039ff8334c24a4c
https://pubmed.ncbi.nlm.nih.gov/34491372
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3
Linkage stratification and mutation analysis at the Parkin locus identifies mutation positive Parkinson's disease families
Autor: William C. Nichols, J. Hubble, H. Fernandez, M. Aminoff, C. O'Brien, D. Truong, D. A. Grimes, A. Rudolph, F. Walker, L. Elmer, S. Factor, R. Kurlan, K. Blindauer, Paul J. Tuite, L. Seeberger, Richard B. Dewey, J. Rao, D. Jennings, P. M. Conneally, R. Pahwa, R. Hauser, W. Koller, T. Ajax, M. Fernandez, J. Sutton, B. Racette, R. Uitti, K. Sethi, A. Feigin, J. Jankovic, R. Pfeiffer, C. Serrano Ramos, M. Stacy, L. Shulman, M. F. Gordon, L. Sudarsky, K. Marek, J. Bertoni, V. Calabresse, M. Velickovic, R. Rodnitzyk, Juan Sanchez-Ramos, Sean K. Uniacke, P. Gordon, A. Dalvi, N. Hermanowicz, T. Zesiewicz, T. Simuni, U. Jung Kang, C. Shults, P. Lewitt, M. Leehey, Mayank Pathak, Tatiana Foroud, J. Carter, R. Saunders Pullman, B. Manyam, M. Panisset, Michael W. Pauciulo, G. D. Podakalny, T. Mendis, D. Simon, J. Friedman, W. Martin, Richard Camicioli, Joanne Wojcieszek, N. Pankratz, C. Halter, K. Marder, S. Reich, A. Nieves, A. Rajput, O. Suchowersky
Publikováno v: Journal of medical genetics. 39(7)
Parkinson's disease (PD) is one of the most common neurological disorders in humans with an overall prevalence of 1:1000 with the incidence increasing to as high as 3.4% among people aged 75 years.1,2 The clinical phenotype includes resting tremor, m
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b725632ddb901f816fec5360003567d7
https://pubmed.ncbi.nlm.nih.gov/12114481
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4
Paper curl prediction - neural networks applied to the papermaking industry
Autor: Alan F. Murray, P. J. Edwards, A. R. Wallace, G. Papadopoulos, J. Barnard, M. F. Gordon
Publikováno v: 9th International Conference on Artificial Neural Networks: ICANN '99.
This paper describes the application of neural network techniques to the papermaking industry, particularly for the prediction of paper “curl”. Paper curl is a common problem and can only be measured reliably off-line, after manufacture. Conventi
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::c9907439fa5def53eaed6b317865ab36
https://doi.org/10.1049/cp:19991131
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6
The use of clozapine in neurologic disorders
Autor: A Z, Safferman, J M, Kane, J S, Aronowitz, M F, Gordon, S, Pollack, J A, Lieberman
Publikováno v: The Journal of clinical psychiatry. 55
The advent of clozapine has marked a major advance in the treatment of schizophrenia because of its low incidence of extrapyramidal side effects and superior efficacy. Because of a relatively high incidence of agranulocytosis, approved indications fo
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::8a4ce027b3515b2db90f6a48ee1df2c7
https://pubmed.ncbi.nlm.nih.gov/7961585
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7
A study of idiopathic torsion dystonia in a non-Jewish family: evidence for genetic heterogeneity
Autor: Laurie J. Ozelius, Carol Moskowitz, Neil Risch, Patricia L. Kramer, Xandra O. Breakefield, T. G. Nygaard, M. F. Gordon, Gary A. Heiman, Robert E. Burke, Stanley Fahn, A. L. Hunt, Susan B. Bressman, Mitchell F. Brin, Deborah de Leon
Publikováno v: Neurology. 44(2)
A gene (DYT1) for idiopathic torsion dystonia (ITD) was mapped to chromosome 9q34 in non-Jewish and Jewish families; the dystonia in these families usually began in childhood, with the limb muscles affected first. The role of the DYT1 gene in adult-o
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2d9ee4a90a6afea00a9f82afd213223f
https://pubmed.ncbi.nlm.nih.gov/8309575
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10
Hemiparkinsonism‐hemiatrophy syndrome
Autor: V. Kostic, Nir Giladi, M. F. Gordon, Robert E. Burke, Serge Przedborski, Stanley Fahn, Ann L. Hunt
Publikováno v: Neurology. 40:1731-1731
We evaluated 11 patients with hemiparkinson-hemiatrophy syndrome, 6 with body and contralateral cerebral hemispheric hemiatrophy, 4 with only body hemiatrophy, and 1 with just brain hemiatrophy. The mean age of symptom onset was 38.1 years (range, 18
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b95439474e504e721f566c9c3dc13891
https://doi.org/10.1212/wnl.40.11.1731
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