Výsledky vyhledávání - "M. F. G. B. Gebbink"

Increased levels of viable circulating endothelial cells are an indicator of progressive disease in cancer patients

Autor: Bernard A. Zonnenberg, Joost S.P. Vermaat, Niven Mehra, M. F. G. B. Gebbink, Emile E. Voest, Laurens V. Beerepoot

Publikováno v: Annals of Oncology. 15:139-145

BACKGROUND There is accumulating evidence from preclinical studies that circulating endothelial cells (CECs) play an important role in neovascularization and tumor growth. The role of CECs in human cancer progression is sparsely investigated. We ther

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ecd39a2c57de07d489ab50b046ec81fb
https://doi.org/10.1093/annonc/mdh017

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Enhanced antitumour efficacy by combining conventional chemotherapy with angiostatin or endostatin in a liver metastasis model

Autor: J. Van Gorp, E. A. te Velde, E. E. Voest, J. M. Vogten, M. F. G. B. Gebbink, I. H. M. Borel Rinkes

Publikováno v: British Journal of Surgery. 89:1302-1309

Background Tumour-induced microvascular networks have become attractive targets in cancer therapy. Strategies that target both tumour cells and vasculature have not been investigated in models of early metastatic colorectal disease. The efficacy of a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f6abc6257c99f534bcd23d97f31a24ad
https://doi.org/10.1046/j.1365-2168.2002.02183.x

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Multi-site phosphorylation of the protein tyrosine phosphatase, PTP1B: identification of cell cycle regulated and phorbol ester stimulated sites of phosphorylation

Autor: Andrew J. Flint, Nicholas K. Tonks, B. R. Franza, D. E. Hill, M. F. G. B. Gebbink

Publikováno v: The EMBO journal. 12(5)

The non-transmembrane protein tyrosine phosphatase, PTP1B, comprises 435 amino acids, of which the C-terminal 114 residues have been implicated in controlling both localization and function of this enzyme. Inspection of the sequence of the C-terminal

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2fad645d49735b72ea002c6dae7f6b6d
https://pubmed.ncbi.nlm.nih.gov/8491187

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Fine mapping of the human receptor-like protein tyrosine phosphatase gene (PTPRM) to 18p11.2 by fluorescence in situ hybridization

Autor: A. Geurts van Kessel, W. H. Moolenaar, M. F. G. B. Gebbink, R.F. Suijkerbuijk

Publikováno v: Cytogenetic and Genome Research. 64:245-246

The isolation of a cDNA encoding a receptor-like protein tyrosine phosphatase, termed RPTPµ, and the assignment of the human gene to chromosome 18 has recently been reported (Gebbink et al., 1991). Using a genomic clone and fluorescence in situ hybr

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::faa03a419c89834b19a267469d78be26
https://doi.org/10.1159/000133598

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