Zobrazeno 1 - 7
of 7
pro vyhledávání: '"M. F. Dennis"'
Publikováno v:
British Journal of Cancer
Large fluctuations in glutathione content were observed on a daily basis using the Tietze enzyme recycling assay in a panel of six human cell lines of varying radiosensitivity. Glutathione content tended to increase to a maximum during exponential ce
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::03c8e9601670afaf816241bf75378bf6
http://europepmc.org/articles/PMC2033930
http://europepmc.org/articles/PMC2033930
Autor:
G M, Tozer, V E, Prise, J, Wilson, R J, Locke, B, Vojnovic, M R, Stratford, M F, Dennis, D J, Chaplin
Publikováno v:
Cancer research. 59(7)
The potential for tumor vascular-targeting by using the tubulin destabilizing agent disodium combretastatin A-4 3-0-phosphate (CA-4-P) was assessed in a rat system. This approach aims to shut down the established tumor vasculature, leading to the dev
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::d5e38f86e987dbb023143de91af5426a
https://pubmed.ncbi.nlm.nih.gov/10197639
https://pubmed.ncbi.nlm.nih.gov/10197639
Publikováno v:
Experimental physiology. 82(2)
Tumour cell survival is intimately related to blood vessel function and so the tumour vasculature represents a novel target for cancer therapy. We have investigated a murine tumour model in which a metal clamp was used to occlude the vascular supply
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::70ea5cb352f4eb35d7ca633ff1ef9bf5
https://pubmed.ncbi.nlm.nih.gov/9129950
https://pubmed.ncbi.nlm.nih.gov/9129950
Autor:
P, Wardman, K I, Priyadarsini, M F, Dennis, S A, Everett, M A, Naylor, K B, Patel, I J, Stratford, M R, Stratford, M, Tracy
Publikováno v:
The British journal of cancer. Supplement. 27
Pulse radiolysis was used to generate radicals from one electron reduction of 1,2,4-benzotriazine-1,4-dioxides (derivatives of tirapazamine), and of imidazo [1,2-a]quinoxaline-4-oxides (analogues of RB90740), which have selective toxicity towards hyp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::e1352babc4e1cbc9f17398ccd796c2e1
https://pubmed.ncbi.nlm.nih.gov/8763850
https://pubmed.ncbi.nlm.nih.gov/8763850
Publikováno v:
The British journal of cancer. Supplement. 27
The free-radical intermediates and the stable products formed on one-electron oxidation of hydroxyguanidine (HOG) were investigated in order to suggest a mechanistic basis for HOG-induced cytotoxicity and cytostasis in leukaemia HL60 cells. The azide
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::3f694f5fb70347abafb89d600a7cd006
https://pubmed.ncbi.nlm.nih.gov/8763874
https://pubmed.ncbi.nlm.nih.gov/8763874
Publikováno v:
The Journal of biological chemistry. 271(8)
Mechanisms of free radical scavenging by the nutritional antioxidant beta-carotene have been investigated by pulse radiolysis. Free radicals, which can initiate the chain of lipid peroxidation, including nitrogen dioxide (NO2.), thiyl (RS.), and sulf
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::d8ffa592a05507cc03a25e7de4e655d9
https://pubmed.ncbi.nlm.nih.gov/8626730
https://pubmed.ncbi.nlm.nih.gov/8626730
Publikováno v:
Cancer research. 55(24)
Oxidative stress is a key process involved in the action of several therapeutic modalities used in cancer treatment. Ischemia reperfusion insult provides a model system for investigating the processes involved in determining the sensitivity of tumor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::4de5d29c1d90efa1dd0017b2f2bce172
https://pubmed.ncbi.nlm.nih.gov/8521386
https://pubmed.ncbi.nlm.nih.gov/8521386