Výsledky vyhledávání - "M. F. Abd-Ellah"

Comparative study of the metabolism of drug substrates by human cytochrome P450 3A4 expressed in bacterial, yeast and human lymphoblastoid cells

Autor: J B Houston, M. F. Abd-Ellah, J. Andrews, T. Friedberg, K. E. Kenworthy, N. L. Randolph, D. J. Carlile

Publikováno v: Xenobiotica. 32:937-947

1. The aim was to compare the metabolic activity of human CYP3A4 expressed in bacteria (E. coli), yeast (S. cerevisiae) and human lymphoblastoid cells (hBl), with the native CYP3A4 activity observed in a panel of human livers. 2. Three CYP3A4 substra

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::94c40c5121fb6653a146332be02a6bfa
https://doi.org/10.1080/00498250210163289

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Nadolol-glibenclamide interaction: relevance to carbohydrate metabolism in hyperglycaemic rats

Autor: M. F. Abd Ellah, A. H. Abdel Aziz, A. M. Moustafa, Mohamed M. Elmazar

Publikováno v: Pharmacological research. 34(1-2)

In the present study, hyperglycaemia was induced by intraperitoneal injection of streptozotocin (65 mg/kg). Treatment with glibenclamide (GB) in a dose of 0.45 or 0.9 mg/kg significantly decreased plasma glucose level in a dose-related manner. Admini

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a07426720288dd35a8a0a21859098ec3
https://pubmed.ncbi.nlm.nih.gov/8981550

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