Zobrazeno 1 - 10
of 41
pro vyhledávání: '"M. Eva Alonso"'
Autor:
Alan M Pittman, Silvia Naranjo, Sanni E Jalava, Philip Twiss, Yussanne Ma, Bianca Olver, Amy Lloyd, Jayaram Vijayakrishnan, Mobshra Qureshi, Peter Broderick, Tom van Wezel, Hans Morreau, Sari Tuupanen, Lauri A Aaltonen, M Eva Alonso, Miguel Manzanares, Angela Gavilán, Tapio Visakorpi, José Luis Gómez-Skarmeta, Richard S Houlston
Publikováno v:
PLoS Genetics, Vol 6, Iss 9, p e1001126 (2010)
Common genetic variation at human 8q23.3 is significantly associated with colorectal cancer (CRC) risk. To elucidate the basis of this association we compared the frequency of common variants at 8q23.3 in 1,964 CRC cases and 2,081 healthy controls. R
Externí odkaz:
https://doaj.org/article/76ea75af14214caa92660695b7398130
Autor:
Evelyn N Kouwenhoven, Simon J van Heeringen, Juan J Tena, Martin Oti, Bas E Dutilh, M Eva Alonso, Elisa de la Calle-Mustienes, Leonie Smeenk, Tuula Rinne, Lilian Parsaulian, Emine Bolat, Rasa Jurgelenaite, Martijn A Huynen, Alexander Hoischen, Joris A Veltman, Han G Brunner, Tony Roscioli, Emily Oates, Meredith Wilson, Miguel Manzanares, José Luis Gómez-Skarmeta, Hendrik G Stunnenberg, Marion Lohrum, Hans van Bokhoven, Huiqing Zhou
Publikováno v:
PLoS Genetics, Vol 6, Iss 8, p e1001065 (2010)
Heterozygous mutations in p63 are associated with split hand/foot malformations (SHFM), orofacial clefting, and ectodermal abnormalities. Elucidation of the p63 gene network that includes target genes and regulatory elements may reveal new genes for
Externí odkaz:
https://doaj.org/article/244a4ff01e8f4721bc59c60b4e933d9a
Autor:
Luis A. Aguirre, José Luis Gómez-Skarmeta, M. Eva Alonso, Ana Fernández-Miñán, Miguel Manzanares, Claudio Badia-Careaga, Elena López-Jiménez, Cristina Arias, Diego Franco, Isabel Rollan, Amelia Aránega
Publikováno v:
Digital.CSIC. Repositorio Institucional del CSIC
instname
BMC Biology
Repisalud
Instituto de Salud Carlos III (ISCIII)
instname
BMC Biology
Repisalud
Instituto de Salud Carlos III (ISCIII)
This is an Open Access article distributed under the terms of the Creative Commons Attribution License.-- et al.
[Background]: Recent genome-wide association studies have uncovered genomic loci that underlie an increased risk for atrial fibrilla
[Background]: Recent genome-wide association studies have uncovered genomic loci that underlie an increased risk for atrial fibrilla
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0651ce36a0fe9b52231045f5a66364a4
http://hdl.handle.net/10261/129624
http://hdl.handle.net/10261/129624
Autor:
M. Eva Alonso, M. Josefa Bello, Dolores Arjona, Victor Martinez-Glez, Jose M. de Campos, Alberto Isla, M. Elena Kusak, Jesús Vaquero, Manuel Gutierrez, Jose L. Sarasa, Juan A. Rey
Publikováno v:
American Journal of Clinical Pathology. 123:900-906
Autor:
M. Josefa Bello, M. Eva Alonso, Jesús Vaquero, Juan A. Rey, Jose M. de Campos, Jesus Lomas, Alberto Isla, Isabel Lopez-Marin, Cinthia Amiñoso, Dolores Arjona, Victor Martinez-Glez
Publikováno v:
Genes, Chromosomes and Cancer. 42:314-319
The role of the NF2 gene in the development of meningiomas has recently been documented; inactivating mutations plus allelic loss at 22q, the site of this gene (at 22q12), have been identified in both sporadic and neurofibromatosis type 2-associated
Autor:
Alberto Isla, Dolores Arjona, M. Eva Alonso, Pilar Gonzalez-Gomez, Jose M. de Campos, Cinthia Amiñoso, Cacilda Casartelli, Jose L. Sarasa, Jesús Vaquero, Juan A. Rey, Manuel Gutierrez, Isabel Lopez-Marin, Nilson Praia Anselmo, M.Elena Kusak, Luis Lassaletta, M. Josefa Bello
Publikováno v:
Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis. 554:23-32
O6-methylguanine-DNA methyltransferase (MGMT) plays a major role in repairing DNA damage from alkylating agents. By removing alkyl groups from the O6-position in guanine, MGMT can prevent G:C to A:T transition mutations, a type of variation frequentl
Autor:
Pilar Gonzalez-Gomez, Cinthia Amiñoso, Dolores Arjona, Jesus Lomas, Isabel Lopez-Marin, M. Josefa Bello, Jose M. de Campos, Jose L. Sarasa, Jesús Vaquero, Juan A. Rey, Manuel Gutierrez, M.Elena Kusak, M. Eva Alonso, Alberto Isla
Publikováno v:
Acta Neuropathologica. 108:413-421
The purpose of this research was to examine the DNA methylation profile of meningiomas. Accordingly, we examined the DNA methylation status of ten tumor-related genes (RB1, p16 INK4a , p73, MGMT, ER, DAPK, TIMP-3, p14 ARF , THBS1, and Caspase-8) in 9
Autor:
Jose M. de Campos, M. Eva Alonso, Juan A. Rey, Manuel Gutierrez, M. Josefa Bello, Dolores Arjona, Pilar Gonzalez-Gomez
Publikováno v:
Journal of Neuro-Oncology. 67:159-165
Aberrant methylation of promoter CpG islands in human genes represents an alternative mechanism for genetic inactivation, and contributes to the development of human tumors. Nevertheless, thus far, few reports have analyzed methylation in ependymomas
Autor:
Juan A. Rey, M. Eva Alonso, Pilar Gonzalez-Gomez, Jose L. Sarasa, Jose M. de Campos, Dolores Arjona, Jesus Lomas, Alberto Isla, M. Josefa Bello
Publikováno v:
Cancer Genetics and Cytogenetics. 144:134-142
Promoter hypermethylation represents a primary mechanism in the inactivation of tumor suppressor genes during tumorigenesis. To determine the frequency and timing of hypermethylation during carcinogenesis of nonastrocytic tumors, we analyzed promoter
Autor:
M. Eva Alonso, Dolores Arjona, Jose M. de Campos, Pilar Gonzalez-Gomez, Cinthia Amiñoso, Jesus Lomas, Juan A. Rey, Manuel Gutierrez, Jose L. Sarasa, M. Josefa Bello
Publikováno v:
Cancer Genetics and Cytogenetics. 142:21-24
We have determined the promoter CpG island methylation status of O(6)-methylguanine-DNA methyltransferase (MGMT), glutathione-S-transferase P1 (GSTP1), death-associated protein kinase (DAPK), p14(ARF), thrombospondin-1 (THBS1), tissue inhibitor of me