Zobrazeno 1 - 10
of 16
pro vyhledávání: '"M. Etienne-Grimaldi"'
Autor:
François-Noël Gilly, A. Abderrahim-Ferkoune, Houry S, Sylviane Olschwang, Daniel Benchimol, Patricia Formento, Jean-Luc Faucheron, Anne Sudaka, Valérie Boige, Bernard Pradère, M.P. Gaub, P. Lasser, A. Mahamat, Maurice Chazal, Jean-Robert Delpero, Gérard Milano, Denis Pezet, Jean-Louis Formento, Thierry André, Frédérique Penault-Llorca, Christian Letoublon, M. Etienne-Grimaldi, Pierre Laurent-Puig
Publikováno v:
British Journal of Cancer
Background: To test the prognostic value of tumour protein and genetic markers in colorectal cancer (CRC) and examine whether deficient mismatch repair (dMMR) tumours had a distinct profile relative to proficient mismatch repair (pMMR) tumours. Metho
Autor:
M. Etienne-Grimaldi, Qingyi Wei, Hyo-Jin Kim, Wei Shu Wang, Seock-Ah Im, Jingrong Yan, Eva Martinez-Balibrea, Ming Yin, Jacques Robert, Francesco Graziano, Heinz-Josef Lenz
Purpose: Nucleotide excision repair (NER) modulates platinum-based chemotherapeutic efficacy by removing drug-produced DNA damage. To summarize published data on the association between polymorphisms of NER genes (ERCC1 and ERCC2) and responses to ox
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7edc7f996e3df13903094df2882e1cfc
https://europepmc.org/articles/PMC3060288/
https://europepmc.org/articles/PMC3060288/
Autor:
Monica Maffi, Cristiana Lo Nigro, Gérard Milano, Federica Tonissi, Marco Merlano, Laura Lattanzio, Jean Louis Fischel, Patricia Formento, Paolo Catarsi, Michela Riba, M. Etienne-Grimaldi, Martino Monteverde
Publikováno v:
Journal of cancer research and clinical oncology. 135(11)
Head and neck squamous cell carcinoma (HNSCC) represents an ideal model for assessing the impact of anemia and tumor hypoxia on the response to radiotherapy (RT). Various treatment strategies aimed at increasing tumor oxygenation in HNSCC patients ha
Autor:
Olivier Guérin, Marco Merlano, Patricia Formento, C. Lo Nigro, M. Etienne-Grimaldi, Jean-Louis Fischel, Gérard Milano, Paul Hofman, J-M Ferrero
Publikováno v:
Journal of cancer research and clinical oncology. 134(1)
Physiological and molecular findings indicate over-expression of HER proteins and dysregulation of neo-angiogenesis during progression of advanced prostate cancer. The aim of this study was to test a novel rational therapeutic approach by combining d
Autor:
Nicole Renée, Laurent Cals, Nicolas Magné, Jean–Louis Formento, M. Etienne-Grimaldi, Gérard Milano, Mireille Francoual
What is already known about this subject • Dihydropyrimidine dehydrogenase (DPD) deficiency is known to be a major cause of severe 5FU-related toxicity. • A link has been previously shown between 5FU toxicity and either low enzyme activity measur
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aa02b6dd0a37d9ce934da056af7030ce
https://europepmc.org/articles/PMC2000632/
https://europepmc.org/articles/PMC2000632/
Autor:
Christine Bobin-Dubigeon, E. Francois, Gérard Milano, Véronique Mari, J. Bennouna, E. Chamorey, M. Etienne-Grimaldi, Nicole Renée, Philippe Follana, Ludovic Evesque
Publikováno v:
Journal of Clinical Oncology. 28:e13116-e13116
e13116 Background: The aim was to describe the PK of Erlo, Cap, and Gem, given in combination in the phase I CAPERGEM trial, performed in advanced pancreatic cancer patients. Methods: This study wa...
Autor:
Pascal Garaud, René-Jean Bensadoun, Mireille Francoual, Dominique Grall, M. Etienne-Grimaldi, Juliette Thariat, D. de Raucourt, E. van-Obberghen Schilling, Gérard Milano, Frédérique Penault-Llorca
Publikováno v:
Journal of Clinical Oncology. 28:TPS268-TPS268
TPS268 Background: PORTc is the standard treatment for resected poor-prognosis HNSCC. However, numerous patients fail. Anti-EGFR agent gefitinib is radiosensitizing. Gefitinib has FDA approval for EGFR-mutated lung cancer patients. CARISSA aims are:
Autor:
Jérôme Barrière, Mireille Francoual, Jean-Louis Formento, M. Etienne-Grimaldi, M. Chefrour, Gérard Milano, Jean-Louis Fischel, Patricia Formento, Nicole Renée, E. Francois
Publikováno v:
Journal of Clinical Oncology. 27:e14583-e14583
e14583 Background: Mutated K-ras protein is a strong predictive factor of cetuximab resistance, bypassing the classical direct inhibitory effect on epidermal growth factor receptor (EGFR) signaling. However, cetuximab is also able to mediate ADCC, wh
Autor:
C. El Hannani, J.-Y. Douillard, E. Francois, Roger Faroux, Jean-Louis Formento, M. Etienne-Grimaldi, J.H. Jacob, J. Bennouna, Gérard Milano, Mireille Francoual
Publikováno v:
Journal of Clinical Oncology. 27:4069-4069
4069 Background: Our purpose was to test the predictive value of germinal gene polymorphisms potentially linked to cetuximab, fluoropyrimidine and irinotecan pharmacodynamics on toxicity, clinical response, time to progression (TTP) and overall survi
Autor:
Jean-Louis Formento, M. Etienne-Grimaldi, F. Maindrault-Goebel, T. Andre, Gérard Milano, Benoist Chibaudel, Gérard Lledo, Mireille Francoual, May Mabro, A. de Gramont
Publikováno v:
Journal of Clinical Oncology. 26:4116-4116
4116 Background: To test the predictive value of germinal gene polymorphisms potentially related to fluorouracil (FU) and oxaliplatin (Oxa) pharmacodynamics on toxicity, response rate, progression-...