Zobrazeno 1 - 10
of 60
pro vyhledávání: '"M. Encarnación Camacho"'
Autor:
Fabio Arias, M. Encarnación Camacho, M. Dora Carrión, Meriem Chayah, Miguel Romero, Juan Duarte, Miguel A. Gallo
Publikováno v:
Journal of Chemistry, Vol 2018 (2018)
Two new families of pyrazoline and thiadiazoline heterocycles have been developed. Their inhibitory activities against two different isoforms of nitric oxide synthase (inducible and neuronal NOS) are reported. The novel derivatives were synthesized c
Externí odkaz:
https://doaj.org/article/59a3c0e1dfad444fb3f3f0b639b7a771
This two volume book is an excellent introduction to this interdisciplinary area, lying on the interface between organic chemistry, biochemistry and medicine. The authors give a comprehensive overview of the field and outline the actual challenges in
Autor:
M. Dora Carrión, Belén Rubio-Ruiz, Francisco Franco-Montalban, Pasquale Amoia, Maria Chiara Zuccarini, Chiara De Simone, M. Encarnación Camacho, Rosa Amoroso, Cristina Maccallini
Publikováno v:
European Journal of Medicinal Chemistry. 248:115112
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bcdf4cc6cef4ce2288c4d903c5745209
https://doi.org/10.1016/j.ejmech.2023.115112
https://doi.org/10.1016/j.ejmech.2023.115112
Autor:
Fabio Arias, Francisco Franco-Montalban, Miguel Romero, Juan Duarte, M. Dora Carrión, M. Encarnación Camacho
Publikováno v:
Digibug. Repositorio Institucional de la Universidad de Granada
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The selective inhibition of inducible nitric oxide synthase (iNOS) has become an interesting goal for the treatment of diseases where the immune and inflammatory response of the organism is involved. Septic shock is one prominent example of this type
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::45941375eda0b915e09da4bd77cfe001
https://doi.org/10.1016/j.bioorg.2022.105637
https://doi.org/10.1016/j.bioorg.2022.105637
Autor:
M. Dora Carrión, Miguel Romero, Francisco Franco-Montalban, M. Encarnación Camacho, Fabio Arias
Publikováno v:
Bioorganic & Medicinal Chemistry. 44:116294
In search of new Nitric Oxide Synthase (NOS) inhibitor agents, two isosteric series of derivatives with an imidamide scaffold (one of them with a hydroxyl group and the other with a carbonyl one) were synthesized and evaluated on inducible (iNOS) and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dbe62c445ecd2c36d4b9e889aa676bf0
https://doi.org/10.1016/j.bmc.2021.116294
https://doi.org/10.1016/j.bmc.2021.116294
Publikováno v:
Current Bioactive Compounds. 12:182-190
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6ab6b18604629e6e373eb0797a62b8ec
https://doi.org/10.2174/1573407212666160511170651
https://doi.org/10.2174/1573407212666160511170651
Autor:
Mariem Chayah, Nerea Fernández-Sáez, Fabio Arias, M. Dora Carrión, M. Encarnación Camacho, Miguel A. Gallo, M. Esther García
Publikováno v:
Archiv der Pharmazie. 349:638-650
The synthesis of different compounds with a quinazolinone, quinazolinthione, or quinazolinimine skeleton and their in vitro biological evaluation as inhibitors of inducible and neuronal nitric oxide synthase (iNOS and nNOS) isoforms are described. Th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::20f8c5e0dd112bfffc5d8e9e13db8092
https://doi.org/10.1002/ardp.201600020
https://doi.org/10.1002/ardp.201600020
Publikováno v:
Magnetic Resonance in Chemistry. 54:793-799
The (1) H and (13) C NMR resonances of seventeen N-alkyl and aryl-N'-[3-hydroxy-3-(2-nitro-5-substitutedphenyl)propyl]-thioureas and ureas (1-17), and seventeen N-alkyl or aryl-N'-[3-(2-amino-5-substitutedphenyl)-3-hydroxypropyl]-thioureas and ureas
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8142dad10f0837ce54a23e2fbc8b27ee
https://doi.org/10.1002/mrc.4455
https://doi.org/10.1002/mrc.4455
Autor:
M. Dora Carrión, Miguel Romero, Mariem Chayah, Miguel A. Gallo, M. Encarnación Camacho, Juan Duarte
Publikováno v:
Digibug. Repositorio Institucional de la Universidad de Granada
instname
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The synthesis and biological evaluation of new types of N,N′-disubstituted thiourea and urea derivatives as inhibitors of both neuronal nitric oxide synthase (nNOS) and inducible nitric oxide synthase (iNOS) are described. These compounds have been
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c2bc3f1769ea6ed77fabd318fc1ce379
https://doi.org/10.1039/c5md00477b
https://doi.org/10.1039/c5md00477b