Zobrazeno 1 - 10
of 12
pro vyhledávání: '"M. Elizabeth Graichen"'
Autor:
Arwen R. Pearson, Paul A. Grimsrud, Sudha Marimanikkupam, M. Elizabeth Graichen, Sean A. Agger, Carrie M. Wilmot, Limei Hsu Jones, Yongting Wang, Teresa De la Mora-Rey, Victor L. Davidson
Publikováno v:
Biochemistry. 43:5494-5502
Paracoccus denitrificans methylamine dehydrogenase (MADH) is an enzyme containing a quinone cofactor tryptophan tryptophylquinone (TTQ) derived from two tryptophan residues (betaTrp(57) and betaTrp(108)) within the polypeptide chain. During cofactor
Autor:
Arwen R. Pearson, Carrie M. Wilmot, Yongting Wang, Aimin Liu, M. Elizabeth Graichen, Victor L. Davidson
Publikováno v:
Biochemistry. 42:7318-7325
The biosynthesis of methylamine dehydrogenase (MADH) from Paracoccus denitrificans requires four genes in addition to those that encode the two structural protein subunits. None of these gene products have been previously isolated. One of these, mauG
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Bioenergetics. 1457(1-2):27-35
A Pathways analysis of the methylamine dehydrogenase–amicyanin–cytochrome c -551i protein electron transfer (ET) complex predicts two sets of ET pathways of comparable efficiency from the type I copper of amicyanin to the heme of cytochrome c -55
Publikováno v:
Biochimica et biophysica acta. 1144(1)
Two soluble proteins, methylamine dehydrogenase and amicyanin, form a physiologically relevant complex in which intermolecular electron transfer occurs. To characterize and quantitate the binding of these two weakly-associating proteins, an ultrafilt
Publikováno v:
Carcinogenesis. 3:851-856
A number of model systems have been developed to study the initiating and promoting phases of neoplastic development in rats liver. Four of these protocols use diethylnitrosamine (DEN) initiation, but employ different methods of promotion. The presen
Publikováno v:
Carcinogenesis. 9:193-198
Administration of the nephrotoxicant mercuric chloride (HgCl2) was found to increase microsomal epoxide hydrolase (EH) activity in the kidneys of Fischer 344 (F344) and Sprague-Dawley (SD) rats, but the increases observed were 2- to 4-fold greater in
Publikováno v:
Toxicology and Applied Pharmacology. 52:45-53
The hepatic microsomal mixed function monooxygenase system (MFO) is the major enzyme system responsible for the activation and deactivation of xenobiotics. This study was designed to compare the hepatic MFO system in Fischer-344 and CD (Sprague-Dawle
Autor:
M. Elizabeth Graichen, John G. Dent
Publikováno v:
Carcinogenesis
Hepatocarcinogens have been shown to cause marked elevation of hepatic microsomal epoxide hydrobase activity in the rat at short intervals after administration. The present studies were designed to characterize 2-acetylaminofluorene (AAF) mediated ep
Publikováno v:
Toxicological Sciences. 5:165-174
Short-term treatment of rats with hepatocarcinogens elicits a consistent pattern of phenotypic changes in hepatic drug metabolizing enzymes, the most striking of which is a marked increase in microsomal epoxide hydrolase (EH) activity. The antihistam