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Effect of itraconazole on the pharmacokinetics of faldaprevir in healthy subjects

Autor: F, Huang, K, Marzin, R, Koenen, K P, Kammerer, N, Strelkowa, M, Elgadi, S, Haertter

Publikováno v: Die Pharmazie. 76(5)

Faldaprevir (FDV), a substrate of CYP3A/P-glycoprotein (P-gp), is a selective inhibitor of the hepatitis C virus (HCV) NS3/4 protease. FDV is currently under clinical development for application in interferon-free treatment regimens for patients with

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::7acbbe8253883ac13d4eaf25762dc087
https://pubmed.ncbi.nlm.nih.gov/33964991

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Akademický článek

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HER3 targeting of adenovirus by fiber modification increases infection of breast cancer cells in vitro, but not following intratumoral injection in mice

Autor: Sheena H. MacLeod, Frank L. Graham, K Agopsowicz, Uma Sankar, Gianluca Bossi, Mary Hitt, M M Elgadi, David Sharon, A Pisio

Publikováno v: Cancer Gene Therapy. 19:888-898

Despite the tremendous potential of adenovirus (Ad) as a delivery vector for cancer gene therapy, its use in clinical settings has been limited, mainly as a result of the limited infectivity in many tumors and the wide tissue tropism associated with

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4ff2dca9cb00ae207b846548f2d4f946
https://doi.org/10.1038/cgt.2012.79

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Investigation by infrared absorption spectroscopy into the chemical mechanisms of the wet process synthesis of some calcium phosphates

Autor: K. Moradi, E. Mejdoubi, M. Elgadi, L. L. Elansari, M. Karroua, A. Essaddek

Publikováno v: Journal de Physique IV (Proceedings). 123:233-236

The present work describes the reactions of wet process synthesis, of some calcium phosphates, such as tricalcium phosphate (Ca 3 (PO 4 ) 2 ) and hydroxyapatite (Ca 1 0 (PO 4 ) 6 (OH) 2 ). These reactions of synthesis are acido-basic reactions betwee

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::735aabc2b6aa16d9d98cb66212521d0a
https://doi.org/10.1051/jp4:2005123041

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Development and study of cement and a phosphocalciques ceramic as medical use

Autor: L. L. Elansari, Belkheir Hammouti, E. Abbaoui, M. Elgadi, E. Mejdoubi, A. Essaddek

Publikováno v: Journal de Physique IV (Proceedings). 123:229-232

The hydroxyapatite (Ca 1 0 (PO 4 ) 6 (OH) 2 ) has a structure and a chemical composition very close to those of the mineral phase of calcified tissues. It is thus used for a long time in orthopedic and odontological surgery. In the past few years, ce

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::429f030e57124ff3b9befddc1afb0dba
https://doi.org/10.1051/jp4:2005123040

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Study of the chemical mechanisms of the reaction of neutralization of calcium hydroxide by phosphoric acid

Autor: L. L. Elansari, A. Lamhamdi, M. Elgadi, E. Mejdoubi, S. Abouricha, A. Essaddek

Publikováno v: Journal de Physique IV (Proceedings). 123:351-354

Calcium phosphates reported in this study, are prepared following an acido-basic reaction between phosphoric acid and calcium hydroxide. These phosphates are the brushite, tricalcium phosphate, hydroxyapatite and oxygenated apatite. The follow-up of

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::1bd35025141a5391dd12ad2942c2b461
https://doi.org/10.1051/jp4:2005123064

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Hepatic Glutaminase Gene Expression in the Tumor-Bearing Rat

Autor: Khaled M. Elgadi, Steve F. Abcouwer, Wiley W. Souba, Barrie P. Bode

Publikováno v: Journal of Surgical Research. 69:33-39

Previous studies have documented an increase in hepatic plasma membrane glutamine transport in the tumor-bearing rat, but the effects of tumor burden on hepatic glutaminase expression have not been carefully studied. The purpose of this study was to

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1b2ba36f90d7abe0d71260c7879e5454
https://doi.org/10.1006/jsre.1997.5000

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