Zobrazeno 1 - 10
of 13
pro vyhledávání: '"M. Edward Quach"'
Autor:
M. Edward Quach
Publikováno v:
Platelets, Vol 33, Iss 6, Pp 817-822 (2022)
Platelet adhesion to the site of vascular damage is a critical early step in hemostasis. The platelet glycoprotein (GP) Ib-IX-V plays a key role in this step via its interaction with immobilized von Willebrand Factor (VWF). In addition to its well-kn
Externí odkaz:
https://doaj.org/article/873cc5b25c7f43a2b0b4e3102633920d
Autor:
Aaron Blanchard, J. Dale Combs, Joshua M. Brockman, Anna V. Kellner, Roxanne Glazier, Hanquan Su, Rachel L. Bender, Alisina S. Bazrafshan, Wenchun Chen, M. Edward Quach, Renhao Li, Alexa L. Mattheyses, Khalid Salaita
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-15 (2021)
The authors have recently developed molecular force microscopy (MFM) which uses fluorescence polarisation to measure cell-surface receptor force orientation. Here they show that structured illumination microscopes, which inherently use fluorescence p
Externí odkaz:
https://doaj.org/article/eb25c5882deb4c9a8bdcaa77f44d63b7
Autor:
Aaron Blanchard, J. Dale Combs, Joshua M. Brockman, Anna V. Kellner, Roxanne Glazier, Hanquan Su, Rachel L. Bender, Alisina S. Bazrafshan, Wenchun Chen, M. Edward Quach, Renhao Li, Alexa L. Mattheyses, Khalid Salaita
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-1 (2021)
Externí odkaz:
https://doaj.org/article/42ad264b3a24425daea024421061ec89
Autor:
Renhao Li, M. Edward Quach
Publikováno v:
J Thromb Haemost
The glycoprotein (GP)Ib-IX receptor complex plays a critical role in platelet physiology and pathology. Its interaction with von Willebrand factor (VWF) on the subendothelial matrix instigates platelet arrest at the site of vascular injury, and is vi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::624f09b9532449cca0eb7894af6c8dcb
https://doi.org/10.1111/jth.15035
https://doi.org/10.1111/jth.15035
Autor:
Wenchun Chen, Alisina Bazrafshan, Anna V. Kellner, Rachel L. Bender, Khalid Salaita, Roxanne Glazier, Joshua M. Brockman, J. Dale Combs, Hanquan Su, Aaron T. Blanchard, M. Edward Quach, Alexa L. Mattheyses, Renhao Li
Publikováno v:
Nature Communications
Nature Communications, Vol 12, Iss 1, Pp 1-15 (2021)
Nature Communications, Vol 12, Iss 1, Pp 1-15 (2021)
Many cellular processes, including cell division, development, and cell migration require spatially and temporally coordinated forces transduced by cell-surface receptors. Nucleic acid-based molecular tension probes allow one to visualize the piconew
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aae3af7b03fad75251e8d1f76871a399
https://doi.org/10.1038/s41467-021-24602-x
https://doi.org/10.1038/s41467-021-24602-x
Autor:
M Edward Quach
Publikováno v:
Platelets. 33(6)
Platelet adhesion to the site of vascular damage is a critical early step in hemostasis. The platelet glycoprotein (GP) Ib-IX-V plays a key role in this step via its interaction with immobilized von Willebrand Factor (VWF). In addition to its well-kn
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ca5cbbddcb8b8dd18e452a63b9f1ca25
https://pubmed.ncbi.nlm.nih.gov/34159884
https://pubmed.ncbi.nlm.nih.gov/34159884
Autor:
M. Edward Quach, Wenchun Chen, François Lanza, Renhao Li, Hans Deckmyn, Yingchun Wang, Bernhard Nieswandt
Publikováno v:
J Thromb Haemost
Background Platelets' initial recognition of endothelial damage proceeds through the interaction between collagen, plasma von Willebrand factor (VWF), and the platelet glycoprotein (GP)Ib-IX complex (CD42). The GPIb-IX complex consists of one GPIbα,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b562df4e3331134fb6d12fc3be9880c5
https://pubmed.ncbi.nlm.nih.gov/33915031
https://pubmed.ncbi.nlm.nih.gov/33915031
Autor:
Alexa L. Mattheyses, Khalid Salaita, Rong Ma, M. Edward Quach, Brian G. Petrich, Florian Schueder, Yuxin Duan, Hiroaki Ogasawara, Joshua M. Brockman, Alisina Bazrafshan, Anna V. Kellner, Aaron T. Blanchard, Renhao Li, Yonggang Ke, Rachel L. Bender, Travis A. Meyer, Roxanne Glazier, Ralf Jungmann, Hanquan Su
Publikováno v:
Nat Methods
Despite the vital role of mechanical forces in biology, it still remains a challenge to image cellular force with sub-100-nm resolution. Here, we present tension points accumulation for imaging in nanoscale topography (tPAINT), integrating molecular
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c56505b286e2896f7c0a48694d10409c
https://pubmed.ncbi.nlm.nih.gov/32929270
https://pubmed.ncbi.nlm.nih.gov/32929270
Autor:
M. Edward Quach, Roxanne Glazier, J. Dale Combs, Joshua M. Brockman, Alexa L. Mattheyses, Renhao Li, Hanquan Su, Alisina Bazrafshan, Khalid Salaita, Rachel L. Bender, Anna V. Kellner, Wenchun Chen, Aaron T. Blanchard
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-1 (2021)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1dac70f210e92e75bbb3eb9e9226f4a1
https://doaj.org/article/42ad264b3a24425daea024421061ec89
https://doaj.org/article/42ad264b3a24425daea024421061ec89
Publikováno v:
J Vis Exp
Many biological cells/tissues sense the mechanical properties of their local environments via mechanoreceptors, proteins that can respond to forces like pressure or mechanical perturbations. Mechanoreceptors detect their stimuli and transmit signals
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::19fc1dd428169f3ae44d12f6b8c2baab
https://doi.org/10.3791/59704
https://doi.org/10.3791/59704