Zobrazeno 1 - 8
of 8
pro vyhledávání: '"M. E. W. Vromans"'
Autor:
F.G. van Zijderveld, L.J.M. van Keulen, M. E. W. Vromans, C. M. A. Thuring, Jan P. M. Langeveld, Torres Sweeney
Publikováno v:
Journal of Comparative Pathology 132 (2005) 1
Journal of Comparative Pathology, 132(1), 59-69
Journal of Comparative Pathology, 132(1), 59-69
Sheep are susceptible experimentally to bovine spongiform encephalopathy (BSE), the clinical signs being indistinguishable from those of scrapie. Because of the possibility of natural ovine BSE infection, laboratory tests are needed to distinguish be
Publikováno v:
Journal of Comparative Pathology. 121:55-63
The scrapie-associated prion protein (PrP Sc ), which is closely associated with scrapie infectivity, accumulates in the brain and lymphoid tissues of sheep with natural scrapie. The most probable portal of entry of the scrapie agent in sheep is the
Autor:
J.P.M. Langeveld, L. J. M. van Keulen, M. E. W. Vromans, B. E. C. Schreuder, M. Poelen-van den Berg, G. Mooij-Harkes, R. H. Meloen
Publikováno v:
Veterinary Pathology. 32:299-308
A converted form of the normal cellular prion protein (PrP) accumulates in the brains of sheep with scrapie. We describe an immunohistochemical method for identifying scrapie-associated PrP (PrPSc) in periodate-lysine-paraformaldehyde-fixed brain tis
Publikováno v:
Apmis 110 (2002) 1
Apmis, 110(1), 23-32
Apmis, 110(1), 23-32
The pathogenesis of scrapie infection was studied in sheep carrying the PrP(VRQ)/PrP(VRQ) genotype, which is associated with a high susceptibility for natural scrapie. The sheep were killed at sequential time points during a scrapie infection coverin
Publikováno v:
Prion Diseases ISBN: 9783211835296
Symposium on the characterization and diagnosis of prion diseases in animal and man.-Tübingen, Germany : s.n., 23-25 September 1999
Symposium on the characterization and diagnosis of prion diseases in animal and man.-Tübingen, Germany : s.n., 23-25 September 1999
Although scrapie has been known for a long time as a natural disease of sheep and goats, the pathogenesis in its natural host still remains unclear. To study the pathogenesis of natural scrapie, we used immunohistochemistry to monitor the deposition
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a1983ed6b9d79632cc8078fd71356879
https://doi.org/10.1007/978-3-7091-6308-5_5
https://doi.org/10.1007/978-3-7091-6308-5_5
Publikováno v:
Veterinary Record 142 (1998) 21
Veterinary Record, 142(21), 564-568
Veterinary Record, 142(21), 564-568
Preliminary findings have indicated that in naturally infected sheep, fully susceptible to scrapie (vRQ-homozygous), PrPSc can be detected in the tonsils approximately one year before the expected onset of clinical disease, whereas no immunostaining
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9d1b42407017f833110e13eccb17da49
https://research.wur.nl/en/publications/tonsillar-biopsy-and-prpsc-detection-in-the-preclinical-diagnosis
https://research.wur.nl/en/publications/tonsillar-biopsy-and-prpsc-detection-in-the-preclinical-diagnosis
Publikováno v:
Nature 381 (1996) 6583
Nature, 381(6583), 563-563
Nature, 381(6583), 563-563
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2aa7ad0ca84a43a93985fc40013df8e8
https://research.wur.nl/en/publications/preclinical-test-for-prion-diseases
https://research.wur.nl/en/publications/preclinical-test-for-prion-diseases
Autor:
M. E. W. Vromans, B. E. C. Schreuder, L.J.M. van Keulen, Jan P. M. Langeveld, R. H. Meloen, G. Mooij-Harkes
Publikováno v:
Journal of Clinical Microbiology, 34(5), 1228-1231
Journal of Clinical Microbiology 34 (1996) 5
Journal of Clinical Microbiology 34 (1996) 5
The scrapie-associated form of the prion protein (PrP(Sc)) accumulates in the brain and lymphoid tissues of sheep with scrapie. In order to assess whether detecting PrP(Sc) in lymphoid tissue could he used as a diagnostic test for scrapie, we studied
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::610021f56976dd765cd497669ed6afb4
https://research.wur.nl/en/publications/immunohistochemical-detection-of-prion-protein-in-lymphoid-tissue
https://research.wur.nl/en/publications/immunohistochemical-detection-of-prion-protein-in-lymphoid-tissue