Zobrazeno 1 - 10
of 22
pro vyhledávání: '"M. E. Van Dort"'
Publikováno v:
Journal of Labelled Compounds and Radiopharmaceuticals. 44:S330-S332
The hormone dependency of prostate cancer is well established and androgen receptor (AR) expression is frequently observed in primary prostate tumors and metastases (1). As a consequence, the development of radioligands that target the AR for prostat
Publikováno v:
Journal of Labelled Compounds and Radiopharmaceuticals. 44:S433-S435
Publikováno v:
Journal of Labelled Compounds and Radiopharmaceuticals. 44:S327-S329
The appropriate treatment strategy for prostate cancer is critically dependent on its accurate staging (1). Current screening techniques (CT, MRI, Ultrasound) fail to reliably distinguish clinically-localized disease from metastatic disease. A reliab
Autor:
Kirk A. Frey, R. Del Rosario, David L. Gildersleeve, Y. W. Jung, G.K. Mulholland, Donald M. Wieland, M. E. Van Dort, David M. Raffel, David E. Kuhl, Phillip S. Sherman
Publikováno v:
ChemInform. 27
Publikováno v:
Journal of neural transmission (Vienna, Austria : 1996). 109(10)
Meta-hydroxyephedrine (HED) comprises four stereoisomers consisting of two enantiomeric pairs related to ephedrine and pseudoephedrine. HED is transported into adrenergic neurons and radiolabeled HED has been employed in positron emission tomography
Autor:
A. N. Pinchuk, Richard L. Wahl, M. A. Longino, Raymond E. Counsell, M. E. Van Dort, R.W.S. Skinner, Susan J. Fisher, K. J. Pienta
Publikováno v:
Isotope Production and Applications in the 21st Century.
Publikováno v:
Journal of medicinal chemistry. 43(17)
4-[4, 4-Dimethyl-3-(4-hydroxybutyl)-5-oxo-2-thioxo-1-imidazolidinyl]-2-+ ++trif luoromethylbenzonitrile (RU 59063) is a prototype of a new class of high-affinity nonsteroidal androgen receptor (AR) ligands. The search for a radioiodinated AR ligand p
Autor:
M E, Van Dort
Publikováno v:
Chirality. 11(9)
Methods for the direct chiral chromatographic separation of the four stereoisomers of meta-hydroxyphenylpropanolamine (MHPA) on an analytical and preparative scale are described. Separations were carried out on a Crownpak CR (+) chiral column with 11
Autor:
J C, Sisson, D M, Wieland, R A, Koeppe, D, Normolle, K A, Frey, G, Bolgos, J, Johnson, M E, Van Dort, D L, Gildersleeve
Publikováno v:
Journal of nuclear medicine : official publication, Society of Nuclear Medicine. 32(7)
Myocardial beta adrenergic receptors play important roles in physiology and disease, but the receptors have not before been portrayed. The beta antagonist, iodocyanopindolol (ICYP), was used to develop a scintigraphic method for depicting the recepto
Autor:
K C, Rosenspire, M S, Haka, M E, Van Dort, D M, Jewett, D L, Gildersleeve, M, Schwaiger, D M, Wieland
Publikováno v:
Journal of nuclear medicine : official publication, Society of Nuclear Medicine. 31(8)
Carbon-11-meta-hydroxyephedrine is a new radiotracer developed for mapping the sympathetic nerves of the heart. Carbon-11-meta-hydroxyephedrine is synthesized by direct N-methylation of metaraminol with [11C]methyl iodide in dimethyl formamide/dimeth