Zobrazeno 1 - 9 of 9 pro vyhledávání: '"M. E. Miele"'
1
Percent free PSA as an additional measure in a prostate cancer screen
Autor: M E, Miele
Publikováno v: Clinical laboratory science : journal of the American Society for Medical Technology. 14(2)
To assess the ability of the ratio of free prostate specific antigen to total prostate specific antigen (% fPSA) to aid in selection of subjects who would require follow-up studies.Retrospective, nonrandomized analysis measuring total prostate specif
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::fa0a9cbd29c23e8c7c3f560bf7d47f83
https://pubmed.ncbi.nlm.nih.gov/15625982
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2
A human melanoma metastasis-suppressor locus maps to 6q16.3-q23
Autor: M E, Miele, M D, Jewett, S F, Goldberg, D L, Hyatt, C, Morelli, F, Gualandi, P, Rimessi, D J, Hicks, B E, Weissman, G, Barbanti-Brodano, D R, Welch
Publikováno v: International journal of cancer. 86(4)
Loss, deletion or rearrangement along large portions of the long arm (q-arm) of chromosome 6 occurs in80% of late-stage human melanomas, suggesting that genes controlling malignant characteristics are encoded there. Metastasis, but not tumorigenicity
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::9f6e2587c64273af727239ecf9b8c9c2
https://pubmed.ncbi.nlm.nih.gov/10797266
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3
Suppression of human melanoma metastasis following introduction of chromosome 6 is independent of NME1 (Nm23)
Autor: M E, Miele, A, De La Rosa, J H, Lee, D J, Hicks, J U, Dennis, P S, Steeg, D R, Welch
Publikováno v: Clinicalexperimental metastasis. 15(3)
Metastasis is suppressed more than 95% following microcell-mediated transfer of a single copy of neomycin-tagged human chromosome 6 (neo6) into the human melanoma cell lines C8161 and MelJuSo. Concomitant with metastasis suppression is upregulation o
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::ed97627abf0703bfc81323463b9579cf
https://pubmed.ncbi.nlm.nih.gov/9174127
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4
Metastasis suppressed, but tumorigenicity and local invasiveness unaffected, in the human melanoma cell line MelJuSo after introduction of human chromosomes 1 or 6
Autor: M E, Miele, G, Robertson, J H, Lee, A, Coleman, C T, McGary, P B, Fisher, T G, Lugo, D R, Welch
Publikováno v: Molecular carcinogenesis. 15(4)
Progression of human melanoma toward increasing malignant behavior is associated with several nonrandom chromosomal aberrations, most commonly involving chromosomes 1, 6, 7, 9, and 10. We previously showed that introduction of human chromosome 6 into
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::b32334933f66f4926cb04c38e6cb354d
https://pubmed.ncbi.nlm.nih.gov/8634087
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5
Suppression of MDA-MB-435 breast carcinoma cell metastasis following the introduction of human chromosome 11
Autor: K K, Phillips, D R, Welch, M E, Miele, J H, Lee, L L, Wei, B E, Weissman
Publikováno v: Cancer research. 56(6)
To determine the relevance of genetic information on chromosome 11 in the development of metastatic breast tumors, we introduced a normal human chromosome 11 into the highly metastatic MDA-MB-435 breast carcinoma cell line via the microcell-mediated
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::a19436c79724a41e61b6a516ff4e4a66
https://pubmed.ncbi.nlm.nih.gov/8640802
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6
p53-independent increase in p21WAF1 and reciprocal down-regulation of cyclin A and proliferating cell nuclear antigen in bromodeoxyuridine-mediated growth arrest of human melanoma cells
Autor: M, Strasberg Rieber, D R, Welch, M E, Miele, M, Rieber
Publikováno v: Cell growthdifferentiation : the molecular biology journal of the American Association for Cancer Research. 7(2)
Differentially regulated expression of activators and inhibitors of cyclin-dependent kinases (cdks) modulate cell cycle progression. In normal fibroblasts, these complexes consist of the cdk inhibitor p21WAF1/PCNA/G1 cyclin/cdk. We now show that brom
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::95b9e70bfdad52bb09b02666ab0967ba
https://pubmed.ncbi.nlm.nih.gov/8822203
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7
SOD2 (MnSOD) does not suppress tumorigenicity or metastasis of human melanoma C8161 cells
Autor: M E, Miele, C T, McGary, D R, Welch
Publikováno v: Anticancer research. 15(5B)
Manganese superoxide dismutase (MnSOD, encoded by the SOD2 gene mapping to chromosome 6q25) has been implicated as a tumor suppressor and as a metastasis suppressor in some tumor cell lines. We showed that introduction of an intact chromosome 6 into
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::c3d88bbcb36f8b0d258a6fe16465be73
https://pubmed.ncbi.nlm.nih.gov/8572603
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8
Microcell-mediated transfer of chromosome 6 into metastatic human C8161 melanoma cells suppresses metastasis but does not inhibit tumorigenicity
Autor: D R, Welch, P, Chen, M E, Miele, C T, McGary, J M, Bower, E J, Stanbridge, B E, Weissman
Publikováno v: Oncogene. 9(1)
Structural alterations of chromosome 6, including del(6q), are often associated with metastatic melanoma; therefore, we hypothesized that a metastasis-suppressor gene could be coded on human chromosome 6. Highly metastatic C8161 human malignant melan
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::497e864d2d180257b39cb6e93c74f94d
https://pubmed.ncbi.nlm.nih.gov/8302587
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