Zobrazeno 1 - 5
of 5
pro vyhledávání: '"M. E. Lajiness"'
Autor:
H. H. M. Van Tol, Marc G. Caron, M. F. Piercey, M. E. Lajiness, C. L. Chio, C. A. Tamminga, A. Carlsson, J. C. Schwartz, Rita M. Huff
Publikováno v:
Clinical Neuropharmacology. 18:S25-S33
Autor:
L A, van Vliet, N, Rodenhuis, D, Dijkstra, H, Wikström, T A, Pugsley, K A, Serpa, L T, Meltzer, T G, Heffner, L D, Wise, M E, Lajiness, R M, Huff, K, Svensson, S, Sundell, M, Lundmark
Publikováno v:
Journal of medicinal chemistry. 43(15)
Benzopyranoxazine (+)-7 (PD 128907) is the most dopamine (DA) D3 receptor-selective agonist presently known. The only structural feature which distinguishes 7 from the analogous nonselective naphthoxazines is an oxygen atom in the 6-position. To exte
Publikováno v:
Advances in pharmacology (San Diego, Calif.). 42
Publikováno v:
Molecular pharmacology. 45(1)
Recombinant rat D3 dopamine receptors heterologously expressed in Chinese hamster ovary (CHO) cells are functionally coupled to endogenous G proteins. The affinity of the receptors for agonists is regulated by guanine nucleotides in the same manner a
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 267(3)
Several neurotransmitters that act through G protein-linked receptors have been shown to affect the growth rate of dividing cells. An analysis of the early signaling events that mediate this response revealed some novel activities for G protein-linke