Výsledky vyhledávání - "M. E. Kitler"

Elderly hypertensives and quality of life: some methodological considerations

Autor: M. E. Kitler

Publikováno v: European Heart Journal. 14:113-121

Management of mild hypertension in the elderly aims at symptom relief and a change in the natural history of hypertension. This is often difficult, since mild hypertension is generally symptomless but drug therapy may have serious quality of life seq

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0f8f97e7f7e514064b3cd6987ed945b9
https://doi.org/10.1093/eurheartj/14.1.113

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Coronary disease: are there gender differences?

Autor: M. E. Kitler

Publikováno v: European heart journal. 15(3)

Prevalance rates from hypertensive heart disease are higher for women, while men have higher prevalance rates for coronary heart disease. Female gender is associated with increased mortality after acute MI. Females have also been shown to respond dif

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e8fa3688d72b1a5a37a32a1bdaa47c88
https://pubmed.ncbi.nlm.nih.gov/8013521

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Preventing postoperative acute bleeding of the upper part of the gastrointestinal tract

Autor: M E, Kitler, A, Hays, J P, Enterline, M, Allo, G D, Zuidema

Publikováno v: Surgery, gynecologyobstetrics. 171(5)

Two hundred and ninety-eight critically ill patients at risk for the development of postoperative stress ulcers and bleeding were randomized into three groups. The first group comprised 85 patients who received meciadanol, a new bioflavonoid, 500 mil

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::2d981c2817fa512e88b66d2164ff107d
https://pubmed.ncbi.nlm.nih.gov/2237719

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Clinical trials in hypertension: the present and perspectives for the future

Autor: M E, Kitler

Publikováno v: Journal of hypertension. Supplement : official journal of the International Society of Hypertension. 8(4)

Testing antihypertensive drugs solely for their efficacy and safety does not meet modern therapeutic demands. Clinicians need to know how drugs behave during an overdose and how they affect a patient's quality of life. In the future, health economist

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::a356e8b513ebde783b621184aec69a77
https://pubmed.ncbi.nlm.nih.gov/2258781

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Clinical trials in the elderly. Pivotal points

Autor: M E, Kitler

Publikováno v: Clinics in geriatric medicine. 6(2)

A clinical trial, that is, the scientific assessment of drug action in humans, must be undertaken only if there is reference to an expectation of benefit from the trial. Before the trial starts, a series of questions should be answered, including the

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::32cb7d6e147986ff380bddd630b4eafa
https://pubmed.ncbi.nlm.nih.gov/2184921

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Irish society of gastroenterology

Autor: P. O’Byrne, P. Collins, A. Johnson, M. Ledwith, B. Lane, D. Bouchier-Hayes, P. MacMathuna, T. O’Reilly, M. Barry, A. Duanes-Laita, J. Feely, P. W. N. Keeling, P. Cotter, G. Burke, R. Waldron, M. J. Zinner, B. M. Jaffe, F. Givan, G. Keye, P. Byrne, M. O’Brien, Cliona O’Farrelly, F. Stevens, C. McCarthy, C. Feighery, D. G. Weir, M. C. Hannigan, F. M. Stevens, C. F. McCarthy, P. F. Fottrell, M. P. O’Connor, N. P. Kennedy, M. G. Courtney, D. Kelleher, D. W. Weir, A. Senapati, M. E. Kitler, R. P. H. Thompson, B. O’Shea, D. Madigan, P. Keeling, T. P. J. Hennessy, John J. Meenan, Eoin F. Gaffney, J. P. Duigan, A. H. Johnson, P. B. Collins, M. V. Healy, R. Skehill, H. Grimes, C. O’Farrelly, J. Kelly, R. Rees, H. Hoey, H. Humphreys, C. Dooley, D. O’Leary, S. Bourke, D. McKenna, B. Power, C. Keane, E. Sweeney, C. A. O’Morain, N. H. Afdhal, A. McCormick, D. P. O’Donoghue, E. M. M. Quigley, L. A. Turnberg, R. J. Moorehead, Margaret Hoper, S. T. D. McKelvey, I. Tobbia, R. Rafferty, P. Gillen, R. Stuart, K. Dawson, J. S. A. Collins, J. A. McKnigh, P. C. Pyper, A. H. G. Love, M. E. Dillon, E. O’Connor, P. J. Broe, P. I. Harte, T. Keane, W. I. H. Garstin, K. D. Buchanan, J. P. Walsh, F. J. Bloomfield, W. J. Maxwell, F. P. Hogan, Vincent P. O’Malley, Russell G. Postier, M. Lombard, C. Craven, S. Spencer, J. Crowe, Fergal Quinn, John L. Templeton, M. V. Tobin, S. Hughes, I T. Gilmore, R. M. Keane, A. B. Johnson, A. Duenas-Laita, K. Younger, T. O’Brien, J. Cotter, T. Cullinane, M. J. Whelton, D. Waldron, K. Bowes, H. F. Given, W. F. Gawley, T. F. Gorey, D. H. Osborne, B. E. Lane, P. G. Collins, V. E. Boston, C. O’Mahony

Publikováno v: Irish Journal of Medical Science. 155:239-252

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::30820ef6034b617011f52cdc95f8d41f
https://doi.org/10.1007/bf02962975

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Clinical trials: A practical tool in cardiology

Autor: M. E. Kitler

Publikováno v: European Heart Journal. 9:203-206

A number of major clinical trials have addressed the issue of the management of hypertension, but only a few have looked exclusively at elderly patients. While these trials have brought about new approaches to the chronic management of hypertension,

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::ee670df0264d3b4d6623fda8f81b9234
https://doi.org/10.1093/oxfordjournals.eurheartj.a062483

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The changing face of clinical trials

Autor: M E, Kitler

Publikováno v: Journal of hypertension. Supplement : official journal of the International Society of Hypertension. 6(1)

We have now seen 20 years of clinical trials testing the efficacy and safety of antihypertensive drugs, involving more than 40,000 patients internationally. Much has been learned and should be applied to future studies. First, patient selection: will

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::0c8fa098000cc06f58f7290d43c9a94b
https://pubmed.ncbi.nlm.nih.gov/3063796

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Effect of meciadanol on gastric secretion and aspirin-induced gastric mucosal injury in humans

Autor: S J, Konturek, M E, Kitler, N, Kwiecien, W, Obtulowicz, J, Oleksy, B, Kopp

Publikováno v: Scandinavian journal of gastroenterology. 19(8)

The aim of this study was to assess the effects of a newly synthesized flavonoid, meciadanol, on gastric secretion and on aspirin-induced gastric mucosal injury in healthy humans. In vitro experiments have shown that meciadanol (INN proposed) inhibit

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::ba828404f328f39e1f27f62d78a681f8
https://pubmed.ncbi.nlm.nih.gov/6442798

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