Genomic signatures of inbreeding in a critically endangered parrot, the kākāpō

Autor: Yasmin Foster, Ludovic Dutoit, Stefanie Grosser, Nicolas Dussex, Brodie J Foster, Ken G Dodds, Rudiger Brauning, Tracey Van Stijn, Fiona Robertson, John C McEwan, Jeanne M E Jacobs, Bruce C Robertson

Publikováno v: G3: Genes, Genomes, Genetics, Vol 11, Iss 11 (2021)

AbstractEvents of inbreeding are inevitable in critically endangered species. Reduced population sizes and unique life-history traits can increase the severity of inbreeding, leading to declines in fitness and increased risk of extinction. Here, we i

Externí odkaz: https://doaj.org/article/691d856f37f84ad3bb89f44f9fedf692

Metabolic impact of genetic and chemical ADP/ATP carrier inhibition in renal proximal tubule epithelial cells

Autor: Charlotte A. Hoogstraten, Maaike M. E. Jacobs, Guido de Boer, Melissa A. E. van de Wal, Werner J. H. Koopman, Jan A. M. Smeitink, Frans G. M. Russel, Tom J. J. Schirris

Publikováno v: Archives of Toxicology, 97, 1927-1941
Archives of Toxicology, 97, 7, pp. 1927-1941

Mitochondrial dysfunction is pivotal in drug-induced acute kidney injury (AKI), but the underlying mechanisms remain largely unknown. Transport proteins embedded in the mitochondrial inner membrane form a significant class of potential drug off-targe

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::624b90cdb0fa6ad59940574f54a19058
https://hdl.handle.net/2066/293800

Genetic Diversity in Invasive Populations of Argentine Stem Weevil Associated with Adaptation to Biocontrol

Autor: Thomas W. R. Harrop, Marissa F. Le Lec, Ruy Jauregui, Shannon E. Taylor, Sarah N. Inwood, Tracey van Stijn, Hannah Henry, John Skelly, Siva Ganesh, Rachael L. Ashby, Jeanne M. E. Jacobs, Stephen L. Goldson, Peter K. Dearden

Publikováno v: Insects, Vol 11, Iss 7, p 441 (2020)

Modified, agricultural landscapes are susceptible to damage by insect pests. Biological control of pests is typically successful once a control agent has established, but this depends on the agent’s capacity to co-evolve with the host. Theoretical

Externí odkaz: https://doaj.org/article/1240ab2e37534e58a7d414dd7d84a327

Treatment of prosthetic joint infections due to Propionibacterium: Similar results in 60 patients treated with and without rifampicin

Autor: Anouk M E Jacobs, Miranda L Van Hooff, Jacques F Meis, Fidel Vos, Jon H M Goosen

Publikováno v: Acta Orthopaedica, Vol 87, Iss 1, Pp 60-66 (2016)

Background and purpose — Currently, Propionibacterium is frequently recognized as a causative microorganism of prosthetic joint infection (PJI). We assessed treatment success at 1- and 2-year follow-up after treatment of Propionibacterium-associate

Externí odkaz: https://doaj.org/article/273b22244f3c4822af199fe3776a34de

Ruling out underlying infection in 200 presumed aseptic knee and hip revision arthroplasties using a multiplex PCR system

Autor: Petra J. C. Heesterbeek, Jon H M Goosen, Jacques F. Meis, Anouk M E Jacobs, Frans A. T. Bovendeert, Saskia Susan

Publikováno v: European Journal of Clinical Microbiology and Infectious Diseases, 40, 6, pp. 1283-1290
European Journal of Clinical Microbiology and Infectious Diseases, 40, 1283-1290

Contains fulltext : 245230.pdf (Publisher’s version ) (Closed access) Ruling out an infection in one-stage knee and hip revisions for presumed aseptic failure by conventional tissue cultures takes up to 14 days. Multiplex polymerase chain reaction

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c0ef479b43f85dcb98cf57a1ed3fdf02
https://hdl.handle.net/2066/245230