Výsledky vyhledávání - "M. E. Halloran"

The contribution of neighbours to an individual's risk of typhoid outcome

Autor: M. E. Halloran, R. L. Ochiai, Dennis L. Chao, Florian Marks, Ira M. Longini, J. K. Park

Publikováno v: Epidemiology and Infection

SUMMARYAn individual's risk of infection from an infectious agent can depend on both the individual's own risk and protective factors and those of individuals in the same community. We hypothesize that an individual's exposure to an infectious agent

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::41ece73e8203aed7408797490b93eb79
https://doi.org/10.1017/s0950268815000692

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Household transmissibility of avian influenza A (H7N9) virus, China, February to May 2013 and October 2013 to March 2014

Autor: W. Cao, J. Hu, E. Chen, S. Liang, Ye Zhang, Yang Yang, M. E. Halloran, Eben Kenah, Tom Britton, Fenyang Tang, Li Qun Fang, Zijian Feng, Ira M. Longini, M. Ma

To study human-to-human transmissibility of the avian influenza A (H7N9) virus in China, household contact information was collected for 125 index cases during the spring wave (February to May 2013), and for 187 index cases during the winter wave (Oc

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::23746fcfbe2047924974357de8639cf4
https://europepmc.org/articles/PMC4404303/

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Assessing the impact of travel restrictions on international spread of the 2014 West African Ebola epidemic

Autor: Marcelo F. C. Gomes, Ira M. Longini, Livio Bioglio, Dennis L. Chao, A Pastore y Piontti, M. E. Halloran, Loïc Rossi, Alessandro Vespignani, Vittoria Colizza, Chiara Poletto

Publikováno v: Eurosurveillance
Eurosurveillance, 2014, 19 (42), pp.2. ⟨10.2807/1560-7917.ES2014.19.42.20936⟩
Europe PubMed Central
Eurosurveillance, European Centre for Disease Prevention and Control, 2014, 19 (42), pp.2. ⟨10.2807/1560-7917.ES2014.19.42.20936⟩
Scopus-Elsevier

International audience; The quick spread of an Ebola outbreak in West Africa has led a number of countries and airline companies to issue travel bans to the affected areas. Considering data up to 31 Aug 2014, we assess the impact of the resulting tra

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::801ce6f5ba40acdf3736bf8414a8bae4
https://europepmc.org/articles/PMC4415609/

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Statistical Issues in Phase III Human Immunodeficiency Virus Vaccine Trial Design

Autor: M. E. Halloran

Publikováno v: Journal of the Royal Statistical Society Series A: Statistics in Society. 161:265-272

Summary Several scientific questions are of interest in phase III trials of prophylactic human immunodeficiency virus (HIV) vaccines. In this paper we focus on some issues related to evaluating the direct protective effects of a vaccine in reducing s

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::a6f47073197c9288606b33a2df886897
https://doi.org/10.1111/1467-985x.00104

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Population Biology, Evolution, and Immunology of Vaccination and Vaccination Programs

Publikováno v: The American Journal of the Medical Sciences. 315:76-86

The purpose of prophylactic vaccination is to reduce morbidity and mortality in a population. Many questions related to the design of vaccines and vaccination programs require a population standpoint for their sharp formulation and laboratory and fie

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::f4ea4a91ffe64f68818d81ba05fc7f11
https://doi.org/10.1016/s0002-9629(15)40281-2

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Randomization and baseline transmission in vaccine field trials

Autor: M. E. Halloran, Claudio J. Struchiner

Publikováno v: Epidemiology and infection. 135(2)

In randomized trials, the treatment assignment mechanism is independent of the outcome of interest and other covariates thought to be relevant in determining this outcome. It also allows, on average, for a balanced distribution of these covariates in

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e5d594fe255be4a4f5503528c4bcc5d9
https://pubmed.ncbi.nlm.nih.gov/17291359

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Salmonella enteritidis infections in France and the United States: causes vs causal models

Autor: M E Halloran

Publikováno v: American Journal of Public Health. 83:1667-1669

OBJECTIVES. Epidemiological surveillance can be used to identify problems, suggest hypotheses, and assess the effectiveness of preventive actions. These objectives are pursued in the analysis of the dynamic evolution of Salmonella enteritidis infecti

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6b7f2cf5fdd824bd1dd87eec6e3a1215
https://doi.org/10.2105/ajph.83.12.1667

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A Markov model for measuring vaccine efficacy for both susceptibility to infection and reduction in infectiousness for prophylactic HIV vaccines

Autor: I M, Longini, M G, Hudgens, M E, Halloran, K, Sagatelian

Publikováno v: Statistics in medicine. 18(1)

We use a discrete-time non-homogeneous Markov chain to model data from augmented human immunodeficiency virus (HIV) vaccine trials. For this design, the study population consists of primary participants some of whom have steady sexual partners who ar

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::24482b7c8dafe8e2f9557406431200b6
https://pubmed.ncbi.nlm.nih.gov/9990692

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Semi-parametric models for mismeasured exposure information in vaccine trials

Autor: G T, Golm, M E, Halloran, I M, Longini

Publikováno v: Statistics in medicine. 17(20)

Exposure to infection information is important for estimating vaccine efficacy, but it is difficult to collect and inherently prone to missingness and mismeasurement. It is, therefore, generally not feasible to collect good exposure information on al

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::f22f492d2c28143c70c793e9fcd52a48
https://pubmed.ncbi.nlm.nih.gov/9819831

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Testing for contributions of mitochondrial DNA mutations to complex diseases

Autor: F, Sun, A E, Ashley-Koch, L K, Durham, E, Feingold, M E, Halloran, A K, Manatunga, S L, Sherman

Publikováno v: Genetic epidemiology. 15(5)

Several complex disorders are suspected of being associated with mitochondrial DNA (mtDNA) mutations. We studied the statistical properties of a test based on proband-relative pairs to identify potential mtDNA mutation involvement in a complex disord

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::b23cedf3a8c4a05695a87433fe399416
https://pubmed.ncbi.nlm.nih.gov/9728889

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