Zobrazeno 1 - 10
of 43
pro vyhledávání: '"M. E. Hadley"'
Autor:
M. Lebl, Wayne L. Cody, Ana Maria de Lauro Castrucci, M. E. Hadley, Brian C. Wilkes, Victor J. Hruby
Publikováno v:
International Journal of Peptide and Protein Research. 24:472-479
The highly potent cyclic analogue of alpha-MSH, Ac-[Cys4,Cys10]-alpha-MSH4-13-NH2, was structurally modified in position 4. Four analogues were prepared and their biological activities in the in vitro frog and lizard skin bioassays were determined. I
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f16ef3a0176949759123ef0940407cf0
https://doi.org/10.1111/j.1399-3011.1984.tb03147.x
https://doi.org/10.1111/j.1399-3011.1984.tb03147.x
Publikováno v:
International Journal of Impotence Research. 12:S74-S79
We review our experience with Melanotan II, a non-selective melanocortin receptor agonist, in human subjects with erectile dysfunction (ED). Melanotan II was administered to 20 men with psychogenic and organic ED using a double-blind placebo-controll
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::56e69b8f493b8b187fed547876a4cc0c
https://doi.org/10.1038/sj.ijir.3900582
https://doi.org/10.1038/sj.ijir.3900582
Publikováno v:
Biopolymers. 46:155-167
Results of energy calculations for α-MSH (α-melanocyte stimulating hormone, Ac-Ser1-Tyr2-Ser3-Met4-Glu5-His6-Phe7-Arg8-Trp9-Gly10-Lys11-Pro12-Val13-NH2) and [D-Phe7]α-MSH were used for design of cyclic peptides with the general aim to stabilize di
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5c41a49e080917db821862c25f654e50
https://doi.org/10.1002/(sici)1097-0282(199809)46:3<155::aid-bip3>3.0.co
https://doi.org/10.1002/(sici)1097-0282(199809)46:3<155::aid-bip3>3.0.co
Publikováno v:
Pharmaceutical research. 17(5)
The objective of this study was to evaluate in vitro and in vivo the melanogenic activity of one-month duration Melanotan-I (MT-I) implants prepared using poly (D,L lactide-co-glycolide) polymer.The biological activity of the samples of MT-I released
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::f3dd38e192833ee70d4e9331a4b050ce
https://pubmed.ncbi.nlm.nih.gov/10888312
https://pubmed.ncbi.nlm.nih.gov/10888312
Autor:
M E, Hadley, V J, Hruby, J, Blanchard, R T, Dorr, N, Levine, B V, Dawson, F, al-Obeidi, T K, Sawyer
Publikováno v:
Pharmaceutical biotechnology. 11
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::0c45e7d59fa129bc122f3f76d73838c5
https://pubmed.ncbi.nlm.nih.gov/9760697
https://pubmed.ncbi.nlm.nih.gov/9760697
Publikováno v:
Biopolymers. 46(3)
Results of energy calculations for alpha-MSH (alpha-melanocyte stimulating hormone, Ac-Ser1-Tyr2-Ser3-Met4-Glu5-His6-Phe7-Arg8-Trp9- Gly10-Lys11-Pro12-Val13-NH2) and [D-Phe7] alpha-MSH were used for design of cyclic peptides with the general aim to s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::1d2e2d942f0b91faa1020b1a1988bb72
https://pubmed.ncbi.nlm.nih.gov/9699465
https://pubmed.ncbi.nlm.nih.gov/9699465
Publikováno v:
Biopharmaceuticsdrug disposition. 18(3)
A comparative pharmacokinetic trial was performed with a superpotent synthetic melanotropic peptide, [Nle4-D-Phe7]-alpha-MSHi-13 (melanotan-I or MT-I) given by three routes of administration. Plasma levels were measured by RIA and tanning was quantia
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::1aa809dfd44e33658a8f51b76cbd0e00
https://pubmed.ncbi.nlm.nih.gov/9113347
https://pubmed.ncbi.nlm.nih.gov/9113347
Publikováno v:
Experimental dermatology. 6(1)
The objectives of this research were to determine whether melanotropin receptors are characteristic membrane markers of human epidermal melanocytes. Methodologies were developed to visualize these receptors by light microscopy. Multiple copies (up to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::39c299bbdde36ae41450f6e2b108c295
https://pubmed.ncbi.nlm.nih.gov/9067701
https://pubmed.ncbi.nlm.nih.gov/9067701
Publikováno v:
American journal of veterinary research. 55(11)
Analogues of a melanocyte-stimulating hormone (alpha-MSH) have been documented to be effective in inducing integumental melanogenesis in several species. These melanotropin analogues are more potent than the natural hormone and have prolonged biologi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::96927f5d06258bbf8ac997eef473e5c7
https://pubmed.ncbi.nlm.nih.gov/7879984
https://pubmed.ncbi.nlm.nih.gov/7879984