MIF is a common genetic determinant of COVID-19 symptomatic infection and severity

Autor: J J Shin, W Fan, J Par-Young, M Piecychna, L Leng, K Israni-Winger, H Qing, J Gu, H Zhao, W L Schulz, S Unlu, J Kuster, G Young, J Liu, A I Ko, A Baeza Garcia, M Sauler, A V Wisnewski, L Young, A Orduña, A Wang, K Ocskay, A Garcia-Blesa, P Hegyi, M E Armstrong, P D Mitchell, D Bernardo, A Garami, I Kang, R Bucala

Publikováno v: QJM: An International Journal of Medicine. 116:205-212

Genetic predisposition to coronavirus disease 2019 (COVID-19) may contribute to its morbidity and mortality. Because cytokines play an important role in multiple phases of infection, we examined whether commonly occurring, functional polymorphisms in

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8c3553046f1fa4ca3986de88a94a33d7
https://doi.org/10.1093/qjmed/hcac234

The VEGF-Mediated Cytoprotective Ability of MIF-Licensed Mesenchymal Stromal Cells in House Dust Mite-Induced Epithelial Damage.

Autor: Dunbar H; Kathleen Lonsdale Institute for Human Health Research, Maynooth University, Maynooth, Co. Kildare, Ireland.; Department of Biology, Maynooth University, Maynooth, Co. Kildare, Ireland., Hawthorne IJ; Kathleen Lonsdale Institute for Human Health Research, Maynooth University, Maynooth, Co. Kildare, Ireland.; Department of Biology, Maynooth University, Maynooth, Co. Kildare, Ireland., Tunstead C; Kathleen Lonsdale Institute for Human Health Research, Maynooth University, Maynooth, Co. Kildare, Ireland.; Department of Biology, Maynooth University, Maynooth, Co. Kildare, Ireland., Dunlop M; Kathleen Lonsdale Institute for Human Health Research, Maynooth University, Maynooth, Co. Kildare, Ireland.; Department of Biology, Maynooth University, Maynooth, Co. Kildare, Ireland., Volkova E; Kathleen Lonsdale Institute for Human Health Research, Maynooth University, Maynooth, Co. Kildare, Ireland.; Department of Biology, Maynooth University, Maynooth, Co. Kildare, Ireland., Weiss DJ; Department of Medicine, 226 Health Sciences Research Facility, Larner College of Medicine, University of Vermont, Burlington, Vermont, USA., Santos CCD; The Keenan Research Centre for Biomedical Science of St. Michael's Hospital, Toronto, Ontario, Canada.; Institute of Medical Sciences and Interdepartmental Division of Critical Care, Faculty of Medicine, University of Toronto, Toronto, Ontario, Canada., Armstrong ME; Department of Medicine, Trinity College Dublin and Tallaght Hospital, Dublin, Ireland., Donnelly SC; Department of Medicine, Trinity College Dublin and Tallaght Hospital, Dublin, Ireland., English K; Kathleen Lonsdale Institute for Human Health Research, Maynooth University, Maynooth, Co. Kildare, Ireland.; Department of Biology, Maynooth University, Maynooth, Co. Kildare, Ireland.

Publikováno v: European journal of immunology [Eur J Immunol] 2024 Nov 06, pp. e202451205. Date of Electronic Publication: 2024 Nov 06.

Excessive Physical Activity may not be as Beneficial as Moderate Physical Activity for Vascular Disease Risk in UK Women

Autor: Valerie Beral, Benjamin J Cairns, Gillian K Reeves, Jane Green, M E Armstrong

Publikováno v: International Journal of Epidemiology. 44:i127-i127

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::07b088caa39e232b438816e5150596aa
https://doi.org/10.1093/ije/dyv096.117

Inhibition of cap (m7GpppXm)-dependent endonuclease of influenza virus by 4-substituted 2,4-dioxobutanoic acid compounds

Autor: John A. Lewis, M E Davies, Mcclements William L, Harold G. Selnick, M Bourgeois, J C Hastings, M. E. Armstrong, Joanne E. Tomassini, J. Baldwin, Daria J. Hazuda

Synthesis of influenza virus mRNA is primed by capped and methylated (cap 1, m7GpppXm) RNAs which the virus derives by endonucleolytic cleavage from RNA polymerase II transcripts in host cells. The conserved nature of the endonucleolytic processing p

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::251847ccbd92d754731e807e6d1c214b
https://europepmc.org/articles/PMC188292/

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