Zobrazeno 1 - 4
of 4
pro vyhledávání: '"M. E. A. Bekkers"'
Publikováno v:
Thrombosis and Haemostasis. 78:1249-1254
SummaryDextran is used during surgery as a prophylactic agent to prevent deep venous thrombosis. Recently it has been shown that dextran increases t-PA plasma concentrations in patients. As dextran is a potential ligand for the mannose receptor, we s
Autor:
R. Prevost, M E A Bekkers, P. Los, J.L.M. Heeremans, Daan J.A. Crommelin, Cornelis Kluft, J J Emeis
Publikováno v:
Thrombosis and Haemostasis. 73:488-494
SummaryIn this study, we aimed at improving the therapeutic index of tissue- type Plasminogen Activator (t-PA) as thrombolytic agent in the treatment of myocardial infarction. Liposome-encapsulated t-PA was tested in a rabbit jugular vein thrombosis
Autor:
D.C. Rijken, Dmitri V. Sakharov, Dmitri V. Filippov, A. F. H. Jie, J. H. Van Boom, M. E. A. Bekkers
Publikováno v:
FEBS Letters, 1-3, 537, 6-10
Extracellular matrix (ECM) of tissues, vascular tissue in particular, contains a high concentration of negatively charged glycosaminoglycans (GAGs), which are involved in the regulation of cell motility, cell proliferation and the regulation of enzym
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::07e324cc11b2e70fb8e451ada49c8650
http://resolver.tudelft.nl/uuid:458f3238-c14a-49de-9b0b-0f991cc29c3e
http://resolver.tudelft.nl/uuid:458f3238-c14a-49de-9b0b-0f991cc29c3e
Publikováno v:
Arteriosclerosis, Thrombosis, and Vascular Biology, 6, 21, 943-948
We present the first steps in the elaboration of an approach of extracellular matrix-targeted local drug delivery (ECM-LDD), designed to provide a high concentration, ubiquitous distribution, and long-term retention of a drug within the vessel wall a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e3eba4b9a91f7994bbf09153bab65572
http://resolver.tudelft.nl/uuid:b896986b-113c-4fae-8472-80cb511859d4
http://resolver.tudelft.nl/uuid:b896986b-113c-4fae-8472-80cb511859d4