Zobrazeno 1 - 10
of 34
pro vyhledávání: '"M. Duane Enger"'
Publikováno v:
Cell Biology and Toxicology. 7:35-47
Cd++ inhibits EGF-induced 3H-thymidine incorporation in serum deprived NRK-49F cells in a dose dependent pattern. The underlying mechanisms for this inhibition are largely unknown. EGF-induced myc mRNA accumulation in NRK-49F cells and the effects of
Publikováno v:
Toxicology. 61:195-203
Subpopulations T20 and T27, cloned from the human lung carcinoma line A549, differ significantly in their Cd 2+ cytotoxic response. T27 has an LC 50 of 31 μM Cd 2+ and a cytotoxic response threshold of 5 μM Cd 2+ , whereas the T20s LC 50 is 15 μM
Autor:
M. Duane Enger, Yu-Jian Kang
Publikováno v:
Journal of cellular physiology. 148(2)
Treatment of quiescent cells with serum results concomitantly in an increase in cellular glutathione (GSH) content and growth stimulation. A possible association between the GSH increase and the growth response was examined by studying separately the
Publikováno v:
Toxicology. 62(1)
Human lung carcinoma A549-T27 cells were used to determine the effect of diamide on cadmium accumulation. Treatment of the cells with diamide decreased their cellular glutathione content to 51.6 +/- 7% of control and significantly decreased their cad
Autor:
M. Duane Enger, Yu-Jian Kang
Publikováno v:
Experimental cell research. 187(1)
The relationship between glutathione content and cell growth was investigated in A549 human lung carcinoma cells. A decreased cellular glutathione content was achieved by exposing the cells to L-buthionine-SR-sulfoximine (BSO). It also occurred in th
Autor:
M. Duane Enger, Yu-Jian Kang
Publikováno v:
Toxicology letters. 51(1)
Correlation of cadmium cytotoxicity with cellular glutathione content as it changes during cell growth was examined in human lung carcinoma A549-T27 cells. Cellular glutathione content was found to increase rapidly during the first 24 h of subculture
Autor:
John L. Hanners, M. Duane Enger
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Nucleic Acids and Protein Synthesis. 521:606-618
The relative kinetics of cytoplasmic appearance and polyadenylation were determined for informosomal (ribosome-free) and polysomal (ribosome-associated) mRNAs of cultured Chinese hamster cells. Label appeared in polysomal mRNA 17–20 min and into in
Characterization of postribosomal aminoacyl-tRNA synthetases in cultured Chinese hamster ovary cells
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Nucleic Acids and Protein Synthesis. 562:377-385
Postribosomal aminoacyl-tRNA synthetases from cultured Chinese hamster ovary cells are found in forms of defined size. Sedimentation distribution profiles on calibrated 10–30% (w/v) exponential sucrose gradients in two different buffer systems show
Publikováno v:
Biochemical and Biophysical Research Communications. 93:343-348
The effects of protein synthesis inhibitors, cycloheximide and puromycin, on functional thionein mRNA levels have been examined to further delineate the regulation of thionein gene expression in Cd2+-resistant CHO sublines proficient in Cd2+- or Zn2+
Publikováno v:
Toxicology. 29:101-107
Three cadmium resistant sublines, Cdr20F4, Cdr30F9, and Cdr200T1, resistant to 26, 40, and 145 μm CdCl2, respectively, have been derived from the cadmium sensitive Chinese hamster cell line CHO (resistant to 0.2 μ M CdCl2). The resistance appears t