Zobrazeno 1 - 10
of 158
pro vyhledávání: '"M. Dreßen"'
Autor:
H. Lahm, S. Stieglbauer, I. Neb, S. Doppler, S. Schneider, E. Dzilic, R. Lange, M. Krane, M. Dreßen
Publikováno v:
Stem Cell Research, Vol 69, Iss , Pp 103123- (2023)
TBX5 is a transcription factor (TF) playing essential role during cardiogenesis. It is well known that TF mutations possibly result in non- or additional binding of the DNA due to conformational changes of the protein. We introduced a Holt-Oram Syndr
Externí odkaz:
https://doaj.org/article/bf497e1002d643ad87ee174d5949db35
Autor:
H. Lahm, S. Stieglbauer, I. Neb, S.A. Doppler, S. Schneider, E. Dzilic, R. Lange, M. Krane, M. Dreßen
Publikováno v:
Stem Cell Research, Vol 66, Iss , Pp 103011- (2023)
Although TBX5 plays a major role during human cardiogenesis and initiates and controls limb development, many of its interactions with genomic DNA and the resulting biological consequences are not well known. Existing anti-TBX5-antibodies work very i
Externí odkaz:
https://doaj.org/article/e8ef70d834a844e8b99599610cd867c9
Autor:
M. Dreßen, T. Luzius, H. Lahm, I. Neb, S.A. Doppler, S. Schneider, E. Dzilic, R. Lange, M. Krane
Publikováno v:
Stem Cell Research, Vol 59, Iss , Pp 102662- (2022)
We generated an induced pluripotent stem cell (iPSC) line from a healthy male 29-year-old proband. Adipose fibroblasts (AFs) were reprogrammed using Sendai virus. Generated iPSCs showed typical stem cell morphology. From passage 9 on, iPSCs were free
Externí odkaz:
https://doaj.org/article/b47f3314feee4cf3b95e30a13253baff
Autor:
M. Dreßen, H. Lahm, I. Neb, T. Luzius, S.A. Doppler, S. Schneider, E. Dzilic, R. Lange, M. Krane
Publikováno v:
Stem Cell Research, Vol 58, Iss , Pp 102617- (2022)
The Holt-Oram syndrome (HOS) is a rare autosomal dominant disorder, mostly based on mutations in the TBX5 gene. Patients show malformation of at least one upper limb along with congenital heart defects. The established induced pluripotent stem cell (
Externí odkaz:
https://doaj.org/article/381eafa5ea6e4b4ebde63548d2bd41e8
Autor:
S. Doppler, F. Wirth, H. Lahm, P. Heinisch, M. von Stumm, J. Cleuziou, J. Hörer, R. Lange, M. Dreßen
Publikováno v:
The Thoracic and Cardiovascular Surgeon.
Publikováno v:
The Thoracic and Cardiovascular Surgeon.
Autor:
Y Qin, K Hochkogler, L Lehmann, M Klop, Z Mayer, S Holdenrieder, C Wolf, H Lahm, M Dressen, R Lange, A Petry, A Goerlach
Publikováno v:
European Heart Journal. 43
Background Gestational hypoxia can lead to intrauterine growth restriction (IUGR) and programming of cardiovascular diseases in adulthood via different, although not completely understood, epigenetic mechanisms. We have previously shown that reactive
Autor:
H. Lahm, S. Stieglbauer, I. Neb, S.A. Doppler, S. Schneider, E. Dzilic, R. Lange, M. Krane, M. Dreßen
Publikováno v:
Stem cell research. 66
Although TBX5 plays a major role during human cardiogenesis and initiates and controls limb development, many of its interactions with genomic DNA and the resulting biological consequences are not well known. Existing anti-TBX5-antibodies work very i
Autor:
P. Heinrich, L. Ottelé, E. Dzilic, S. Doppler, H. Sager, M. Dreßen, H. Lahm, R. Lange, M. Krane
Publikováno v:
The Thoracic and Cardiovascular Surgeon.
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