Data from LEF1 Drives a Central Memory Program and Supports Antitumor Activity of Natural Killer T Cells

Autor: Leonid S. Metelitsa, Jeffrey M. Rosen, Erica J. Di Pierro, Cynthia N. Chauvin-Fleurence, Caroline M. Sands, Thorsten Demberg, Janice M. Drabek, Michael S. Wood, Xin Xu, Linjie Guo, Amy N. Courtney, Chunchao Zhang, Julien C. Balzeau, Gengwen Tian, Gabriel A. Barragan, Ho Ngai

Vα24-invariant natural killer T cells (NKT) possess innate antitumor properties that can be exploited for cancer immunotherapy. We have shown previously that the CD62L+ central memory-like subset of these cells drives the in vivo antitumor activity

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b4d6cf153beb90dc3f199a90187225a8
https://doi.org/10.1158/2326-6066.c.6551202

Medio-dorsal thalamic dysconnectivity in chronic knee pain: A possible mechanism for negative affect and pain comorbidity

Autor: Sarina J. Iwabuchi, Marianne M. Drabek, William J. Cottam, Arman Tadjibaev, Ali‐Reza Mohammadi‐Nejad, Stamatios Sotiropoulos, Gwen S. Fernandes, Ana M. Valdes, Weiya Zhang, Michael Doherty, David A. Walsh, Dorothee P. Auer

Publikováno v: The European journal of neuroscience.

The reciprocal interaction between pain and negative affect is acknowledged but pain-related alterations in brain circuits involved in this interaction, such as the mediodorsal thalamus (MDThal), still require a better understanding. We sought to inv

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ccd39547e6e321c8fda04aa35ab52ddc
https://pubmed.ncbi.nlm.nih.gov/36453757

Brain perfusion patterns are altered in chronic knee pain:a spatial covariance analysis of arterial spin labelling MRI

Autor: Weiya Zhang, Thomas Graven-Nielsen, William J. Cottam, Dorothee P. Auer, David A. Walsh, Sarina J. Iwabuchi, Marianne M. Drabek, Lars Arendt-Nielsen, Michael Doherty, Yue Xing, Arman Tadjibaev, Kristian Kjær Petersen, Ana M. Valdes, Gwen Sascha Fernandes

Publikováno v: Iwabuchi, S J, Xing, Y, Cottam, W J, Drabek, M M, Tadjibaev, A, Fernandes, G S, Petersen, K K, Arendt-Nielsen, L, Graven-Nielsen, T, Valdes, A M, Zhang, W, Doherty, M, Walsh, D & Auer, D P 2020, ' Brain perfusion patterns are altered in chronic knee pain : a spatial covariance analysis of arterial spin labelling MRI ', Pain, vol. 161, no. 6, pp. 1255-1263 . https://doi.org/10.1097/j.pain.0000000000001829
Iwabuchi, S J, Xing, Y, Cottam, W J, Drabek, M M, Tadjibaev, A, Fernandes, G S, Petersen, K K, Arendt-Nielsen, L, Graven-Nielsen, T, Valdes, A M, Zhang, W, Doherty, M, Walsh, D & Auer, D P 2020, ' Brain perfusion patterns are altered in chronic knee pain : a spatial covariance analysis of arterial spin labelling MRI ', PAIN . https://doi.org/10.1097/j.pain.0000000000001829

Chronic musculoskeletal pain is a common problem globally. Current evidence suggests that maladapted central pain pathways are associated with pain chronicity, for example, in postoperative pain after knee replacement. Other factors such as low mood,

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b3f9e702a1cc03eff92c699ba4a620a0
https://vbn.aau.dk/da/publications/3a99bcbf-61ff-49a3-bb4a-e512abf26f31

Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.

Towards a brain signature of chronic pain using cerebral blood flow spatial covariance analysis in people with chronic knee pain

Autor: Thomas Graven-Nielsen, Sarina J. Iwabuchi, Lars Arendt-Nielsen, Michael Doherty, Yue Xing, Kristian Kjær Petersen, Gwen Sascha Fernandes, Arman Tadjibaev, Dorothee P. Auer, Ana M. Valdes, David A. Walsh, Weiya Zhang, Marianne M. Drabek, William J. Cottam

Chronic musculoskeletal pain is a common problem globally. Current evidence suggests that maladaptive modulation of central pain pathways is associated with pain chronicity following e.g. chronic post-operative pain after knee replacement. Other fact

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::54c3059d19dd593f08751360615a3345
https://doi.org/10.1101/19008326