Zobrazeno 1 - 10
of 32
pro vyhledávání: '"M. Diocee"'
Publikováno v:
Cancer Research. 81:PS4-26
Background: Developed with retrospective data, the 21-gene recurrence score assay (RS) reduces adjuvant chemotherapy (CTx) use in hormone-positive (HR+), HER2-negative, node-negative breast cancer, justifying the assay’s cost. The TAILORx trial pro
Autor:
Alan Nichol, Caroline Speers, Stuart Peacock, Megan E. Tesch, Rekha M. Diocee, Caroline Lohrisch, Lovedeep Gondara
Publikováno v:
CancerReferences. 128(4)
BACKGROUND The trial assigning individualized options for treatment (Rx) (TAILORx) confirmed the predictive value of the 21-gene recurrence score (RS) assay in hormone receptor (HR)-positive, HER2-negative, node-negative breast cancer and established
Autor:
Caroline Speers, Lovedeep Gondara, J Sun, Stephen Chia, Caroline A. Lohrisch, Nathalie LeVasseur, Rekha M. Diocee
Publikováno v:
Journal of Cancer Research and Clinical Oncology. 146:529-536
Achieving a pathologic complete response (pCR) has been associated with improved long-term outcomes in clinical trials. However, the benefit of achieving pCR across subtypes and its prognostic effect on real-world outcomes has not been well described
Autor:
Winson Y. Cheung, Zachary William Neil Veitch, Stephen Chia, Christine E. Simmons, Rekha M. Diocee, Nathalie LeVasseur, S Lupichuk, Karen King, Pa Tang, R Cossetti, Karen A. Gelmon, OF Khan, Lovedeep Gondara
Publikováno v:
Cancer Research. 79:P1-13
Background: Adjuvant chemotherapy combining anthracyclines and taxanes for early stage breast cancer (ESBC) have demonstrated disease-free survival (DFS) and overall survival (OS) benefits. Among the 3rd generation regimens, 2 options have been favou
Autor:
Alan Nichol, Lovedeep Gondara, E.S. Wai, Rekha M. Diocee, Caroline Speers, Pauline T. Truong, Héctor A. Velásquez García, Sarah Hamilton
Publikováno v:
International Journal of Radiation Oncology*Biology*Physics. 103:381-388
The optimal treatment for patients with extensive pure ductal carcinoma in situ (DCIS) ≥4 cm is controversial. This study evaluates local relapse according to type of local therapy: mastectomy, breast-conserving surgery (BCS) alone, and BCS + radia
Autor:
Rekha M. Diocee, Lovedeep Gondara, J Sun, Caroline Speers, Caroline A. Lohrisch, Stephen Chia
Publikováno v:
Cancer Research. 77:P5-16
Background: Neoadjuvant chemotherapy is a treatment option for breast cancer patients (pts) with locally advanced disease and for pts with operable breast cancer who desire breast conservation. Neoadjuvant therapy also allows for early evaluation of
Autor:
Caroline Lohrisch, Caroline Speers, Rekha M. Diocee, Sara Kristina Taylor, Alan Nichol, Dan Le, Kirsten Allen
Publikováno v:
Journal of Clinical Oncology. 39:543-543
543 Background: We sought to explore the impact of locoregional recurrence (LRR) on survival in breast cancer (BC) patients in British Columbia treated in the modern era. Methods: A retrospective cohort study design identified patients diagnosed with
Autor:
Rinat Yerushalmi, Caroline Lohrisch, Nathalie LeVasseur, Hiten Naik, Caroline Speers, Lovedeep Gondara, Rekha M. Diocee, Karen A. Gelmon
Publikováno v:
Journal of Clinical Oncology. 39:e18791-e18791
e18791 Background: Patients with HER2 positive early-stage breast cancer (ESBC) with residual disease (RD) following neoadjuvant therapy derive benefit from treatment escalation. However, treatment modifications for patients who achieve a complete pa
Autor:
Caroline Lohrisch, Maryam Dosani, Alan Nichol, Rekha M. Diocee, Caroline Speers, Sarah Hamilton, Pauline T. Truong, Lovedeep Gondara
Publikováno v:
Radiotherapy and Oncology. 139:S25-S26
Autor:
Stephen Chia, Alan Nichol, Lovedeep Gondara, Caroline Speers, Christine Simmons, Caroline A. Lohrisch, J Sun, Rekha M. Diocee, Nathalie LeVasseur
Publikováno v:
Journal of Clinical Oncology. 37:e12100-e12100
e12100 Background: The use of neoadjuvant treatment has increased over the past decade due to its ability to assess tumour sensitivity to systemic treatment in vivo, and to downstage women for increased breast conserving surgery. Recent studies have