An optofluidic constriction chip for monitoring metastatic potential and drug response of cancer cells

Autor: Tie Yang, Francesca Bragheri, Roberto Osellame, R. Martinez Vazquez, Paolo Minzioni, Chiara Mondello, M. Di Tano, Ilaria Cristiani, Giovanni Nava, Ilaria Chiodi, M. Veglione, Elena Bianchi

Publikováno v: Integrative biology (Camb., Online) 7 (2015): 477–484. doi:10.1039/C5IB00023H
info:cnr-pdr/source/autori:Martinez Vazquez R, Nava G, Veglione M, Yang T, Bragheri F, Minzioni P, Bianchi E, Di Tano M, Chiodi I, Osellame R, Mondello C, Cristiani I./titolo:An optofluidic constriction chip for monitoring metastatic potential and drug response of cancer cells/doi:10.1039%2FC5IB00023H/rivista:Integrative biology (Camb., Online)/anno:2015/pagina_da:477/pagina_a:484/intervallo_pagine:477–484/volume:7
Integrative biology (Camb., Print) 7 (2015): 477–484. doi:10.1039/c5ib00023h
info:cnr-pdr/source/autori:Vazquez, R. Martinez; Nava, G.; Veglione, M.; Yang, T.; Bragheri, F.; Minzioni, P.; Bianchi, E.; Di Tano, M.; Chiodi, I.; Osellame, R.; Mondello, C.; Cristiani, I./titolo:An optofluidic constriction chip for monitoring metastatic potential and drug response of cancer cells/doi:10.1039%2Fc5ib00023h/rivista:Integrative biology (Camb., Print)/anno:2015/pagina_da:477/pagina_a:484/intervallo_pagine:477–484/volume:7

Cellular mechanical properties constitute good markers to characterize tumor cells, to study cell population heterogeneity and to highlight the effect of drug treatments. In this work, we describe the fabrication and validation of an integrated optof

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d542b80ffe51a5131748545c06b077cc
https://doi.org/10.1039/c5ib00023h

An integrated optofluidic device for single-cell sorting driven by mechanical properties

Autor: Paolo Minzioni, Ilaria Cristiani, Roberto Osellame, R. Martinez Vazquez, Petra Paiè, M. Veglione, Chiara Mondello, M. Di Tano, Giovanni Nava, Tie Yang, Francesca Bragheri

Publikováno v: Lab on a chip
15 (2015): 1262–1266. doi:10.1039/c4lc01496k
info:cnr-pdr/source/autori:Yang T, Paiè P, Nava G, Bragheri F, Vazquez RM, Minzioni P, Veglione M, Di Tano M, Mondello C, Osellame R, Cristiani I./titolo:An integrated optofluidic device for single-cell sorting driven by mechanical properties/doi:10.1039%2Fc4lc01496k/rivista:Lab on a chip (Print)/anno:2015/pagina_da:1262/pagina_a:1266/intervallo_pagine:1262–1266/volume:15

We present a novel optofluidic device for real-time sorting on the basis of cell mechanical properties, measured by optical stretching. The whole mechanism, based on optical forces, does not hamper the viability of the tested cells, which can be used

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fe3dda11aa0e7346fffac81e912e7ab1
https://publications.cnr.it/doc/311841

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